Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties
Main Author: | |
---|---|
Publication Date: | 2004 |
Other Authors: | |
Format: | Article |
Language: | eng |
Source: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Download full: | http://hdl.handle.net/1822/20222 |
Summary: | Biodegradable polymers form a unique class of materials that created an entirely new concept when originally proposed as biomaterials. That is, for the first time, a material performing a structural application was designed to be completely resorbed and to become weaker over time. This concept was first applied successfully with catgut sutures and later, with more arguable results, on bone fixation plates and pins. Current research on new and improved biodegradable polymers is focused on more sophisticated biomedical applications to solve patients' problems with higher efficacy and the least possible pain. One example is tissue engineering, in which a biodegradable scaffold seeded with an appropriate cell type provides a substitute for damaged human tissue while the natural process of regeneration is completed. An overview is given of the degradation properties and mechanisms of biodegradable polymers, their processability and biocompatibility, focusing on the aspects most relevant to biomedical applications. The main families of biodegradable polymeric systems are described and the systems that are commercially available or that are currently being studied and proposed for specific medical applications are reviewed. |
id |
RCAP_c469c94a4d317626c50300d58fff3a5c |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/20222 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their propertiesBiodegradable polymersNatural polymersSynthetic polymersBiocompatibilityDegradationBiomedical applicationsScience & TechnologyBiodegradable polymers form a unique class of materials that created an entirely new concept when originally proposed as biomaterials. That is, for the first time, a material performing a structural application was designed to be completely resorbed and to become weaker over time. This concept was first applied successfully with catgut sutures and later, with more arguable results, on bone fixation plates and pins. Current research on new and improved biodegradable polymers is focused on more sophisticated biomedical applications to solve patients' problems with higher efficacy and the least possible pain. One example is tissue engineering, in which a biodegradable scaffold seeded with an appropriate cell type provides a substitute for damaged human tissue while the natural process of regeneration is completed. An overview is given of the degradation properties and mechanisms of biodegradable polymers, their processability and biocompatibility, focusing on the aspects most relevant to biomedical applications. The main families of biodegradable polymeric systems are described and the systems that are commercially available or that are currently being studied and proposed for specific medical applications are reviewed.Maney PublishingUniversidade do MinhoGomes, Manuela E.Reis, R. L.20042004-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/20222eng0950-660810.1179/095066004225021918http://dx.doi.org/10.1179/095066004225021918info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:11:24Zoai:repositorium.sdum.uminho.pt:1822/20222Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:03:10.868903Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
title |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
spellingShingle |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties Gomes, Manuela E. Biodegradable polymers Natural polymers Synthetic polymers Biocompatibility Degradation Biomedical applications Science & Technology |
title_short |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
title_full |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
title_fullStr |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
title_full_unstemmed |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
title_sort |
Biodegradable polymers and composites in biomedical applications : from catgut to tissue engineering - Part 1 - Available systems and their properties |
author |
Gomes, Manuela E. |
author_facet |
Gomes, Manuela E. Reis, R. L. |
author_role |
author |
author2 |
Reis, R. L. |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Gomes, Manuela E. Reis, R. L. |
dc.subject.por.fl_str_mv |
Biodegradable polymers Natural polymers Synthetic polymers Biocompatibility Degradation Biomedical applications Science & Technology |
topic |
Biodegradable polymers Natural polymers Synthetic polymers Biocompatibility Degradation Biomedical applications Science & Technology |
description |
Biodegradable polymers form a unique class of materials that created an entirely new concept when originally proposed as biomaterials. That is, for the first time, a material performing a structural application was designed to be completely resorbed and to become weaker over time. This concept was first applied successfully with catgut sutures and later, with more arguable results, on bone fixation plates and pins. Current research on new and improved biodegradable polymers is focused on more sophisticated biomedical applications to solve patients' problems with higher efficacy and the least possible pain. One example is tissue engineering, in which a biodegradable scaffold seeded with an appropriate cell type provides a substitute for damaged human tissue while the natural process of regeneration is completed. An overview is given of the degradation properties and mechanisms of biodegradable polymers, their processability and biocompatibility, focusing on the aspects most relevant to biomedical applications. The main families of biodegradable polymeric systems are described and the systems that are commercially available or that are currently being studied and proposed for specific medical applications are reviewed. |
publishDate |
2004 |
dc.date.none.fl_str_mv |
2004 2004-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/1822/20222 |
url |
http://hdl.handle.net/1822/20222 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0950-6608 10.1179/095066004225021918 http://dx.doi.org/10.1179/095066004225021918 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Maney Publishing |
publisher.none.fl_str_mv |
Maney Publishing |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799132436781596672 |