The Body mass index in patients with Multiple Sclerosis: A meta-analysis
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.34624/jshd.v3i1.24946 |
Resumo: | This article is an update of a systematic review and meta-analysis related to BMI levels in patients with multiple sclerosis. 31 studies published between 1997 and 2020 were collected. The main objective of this meta-analysis was to compare BMI levels between patients with MS and healthy controls. We conclude that BMI appears to be significantly lower in patients with MS, compared to healthy controls. However, after a more detailed analysis of the available data, it was realized that there are studies that are not very consistent, affecting the heterogeneity of the analysis. This heterogeneity may be associated with several external factors, such as alcohol and tobacco consumption, which were not taken into account in all included studies. In addition to this, there are still other limitations to consider, due to the lack of detailed information on the characteristics, such as the type of MS, the duration of the disease, the EDSS score or ethnicity, among others. After reducing this heterogeneity it was concluded that contrary to what is described in the literature, BMI does not present significant differences between patients with MS and healthy controls. |
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The Body mass index in patients with Multiple Sclerosis: A meta-analysisThis article is an update of a systematic review and meta-analysis related to BMI levels in patients with multiple sclerosis. 31 studies published between 1997 and 2020 were collected. The main objective of this meta-analysis was to compare BMI levels between patients with MS and healthy controls. We conclude that BMI appears to be significantly lower in patients with MS, compared to healthy controls. However, after a more detailed analysis of the available data, it was realized that there are studies that are not very consistent, affecting the heterogeneity of the analysis. This heterogeneity may be associated with several external factors, such as alcohol and tobacco consumption, which were not taken into account in all included studies. In addition to this, there are still other limitations to consider, due to the lack of detailed information on the characteristics, such as the type of MS, the duration of the disease, the EDSS score or ethnicity, among others. After reducing this heterogeneity it was concluded that contrary to what is described in the literature, BMI does not present significant differences between patients with MS and healthy controls.Este artigo trata-se de uma atualização de uma revisão sistemática e meta-análise relativa aos niveis de BMI em pacientes com esclerose múltipla. Foram reunidos 31 estudos publicados entre 1997 e 2020. O objetivo principal desta meta-análise era comparar os níveis de BMI entre pacientes com EM e controlos saudáveis. Conclui-se que o BMI parece ser significativamente inferior em doentes com MS, relativamente a controlos saudáveis. No entanto, após uma análise mais detalhada dos dados disponíveis, percebeu-se que existem estudos que não são muito concordantes afetando a heterogenidade da análise. Esta heterogeneidade poderá estar associada a diversos fatores externos como o consumo de álcool e tabaco, que não foram tidos em conta em todos os estudos incluídos. Para além disto, existem ainda outras limitações a considerar, devido à falta de informação detalhada das características, como o tipo de EM, a duração da doença, o score EDSS ou a etnia, entre outros. Depois de se reduzir essa heterogeneidade contatou-se que contrariamente ao descrito na literatura, o BMI não apresenta diferenças significativas entre doentes com MS e controlos saudáveis.University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV)2021-07-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.34624/jshd.v3i1.24946oai:proa.ua.pt:article/24946Journal of Statistics on Health Decision; Vol 3 No 1 (2021): Special Issue - Statistics on Health Decision Making: Public Health; 99-104Journal of Statistics on Health Decision; vol. 3 n.º 1 (2021): Special Issue - Statistics on Health Decision Making: Public Health; 99-1042184-5794reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://proa.ua.pt/index.php/jshd/article/view/24946https://doi.org/10.34624/jshd.v3i1.24946https://proa.ua.pt/index.php/jshd/article/view/24946/18309https://proa.ua.pt/index.php/jshd/article/view/24946/18312Copyright (c) 2021 Laura Jesus Jorge Oliveira Castro, Alexandre Pereira, Nuno Ribeirohttp://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessCastro, Laura Jesus Jorge OliveiraPereira, AlexandreRibeiro, Nuno2022-09-06T09:09:17ZPortal AgregadorONG |
dc.title.none.fl_str_mv |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
title |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
spellingShingle |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis Castro, Laura Jesus Jorge Oliveira |
title_short |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
title_full |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
title_fullStr |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
title_full_unstemmed |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
title_sort |
The Body mass index in patients with Multiple Sclerosis: A meta-analysis |
author |
Castro, Laura Jesus Jorge Oliveira |
author_facet |
Castro, Laura Jesus Jorge Oliveira Pereira, Alexandre Ribeiro, Nuno |
author_role |
author |
author2 |
Pereira, Alexandre Ribeiro, Nuno |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Castro, Laura Jesus Jorge Oliveira Pereira, Alexandre Ribeiro, Nuno |
description |
This article is an update of a systematic review and meta-analysis related to BMI levels in patients with multiple sclerosis. 31 studies published between 1997 and 2020 were collected. The main objective of this meta-analysis was to compare BMI levels between patients with MS and healthy controls. We conclude that BMI appears to be significantly lower in patients with MS, compared to healthy controls. However, after a more detailed analysis of the available data, it was realized that there are studies that are not very consistent, affecting the heterogeneity of the analysis. This heterogeneity may be associated with several external factors, such as alcohol and tobacco consumption, which were not taken into account in all included studies. In addition to this, there are still other limitations to consider, due to the lack of detailed information on the characteristics, such as the type of MS, the duration of the disease, the EDSS score or ethnicity, among others. After reducing this heterogeneity it was concluded that contrary to what is described in the literature, BMI does not present significant differences between patients with MS and healthy controls. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-07-22T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.34624/jshd.v3i1.24946 oai:proa.ua.pt:article/24946 |
url |
https://doi.org/10.34624/jshd.v3i1.24946 |
identifier_str_mv |
oai:proa.ua.pt:article/24946 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://proa.ua.pt/index.php/jshd/article/view/24946 https://doi.org/10.34624/jshd.v3i1.24946 https://proa.ua.pt/index.php/jshd/article/view/24946/18309 https://proa.ua.pt/index.php/jshd/article/view/24946/18312 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2021 Laura Jesus Jorge Oliveira Castro, Alexandre Pereira, Nuno Ribeiro http://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2021 Laura Jesus Jorge Oliveira Castro, Alexandre Pereira, Nuno Ribeiro http://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf application/pdf |
dc.publisher.none.fl_str_mv |
University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV) |
publisher.none.fl_str_mv |
University of Aveiro (UA) and Hospital Center of Baixo Vouga (CHBV) |
dc.source.none.fl_str_mv |
Journal of Statistics on Health Decision; Vol 3 No 1 (2021): Special Issue - Statistics on Health Decision Making: Public Health; 99-104 Journal of Statistics on Health Decision; vol. 3 n.º 1 (2021): Special Issue - Statistics on Health Decision Making: Public Health; 99-104 2184-5794 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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1777301333663023104 |