Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants

Detalhes bibliográficos
Autor(a) principal: Melgar Castañeda, Bruno
Data de Publicação: 2018
Outros Autores: Dias, Maria Inês, Ćirić, Ana, Soković, Marina, Garcia-Castello, Esperanza M., Rodriguez-Lopez, Antonio D., Barros, Lillian, Ferreira, Isabel C.F.R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10198/15055
Resumo: Avocado (Persea americana Mill.) is a worldwide consumed fruit, with great interest for cosmetic and pharmaceutical industries; however, 30% of avocado fruits are bio-wastes (peels and kernels), converting them into a potential source of bioactive compounds, such as phenolic compounds. Therefore, the hydroethanolic extracts of peels and kernels of Persea america Mill. var. Hass were analysed regarding their individual phenolic profile by HPLC-DAD/ESI–MS and correlated with their antioxidant, antimicrobial and cytotoxic activities. Avocado by-products presented a very distinct phenolic profile, presenting higher concentration in peels (227.9 mg/g of extract for total phenolic content), mainly in (epi)catechin derivatives (175 mg/g of extract), followed by chlorogenic derivatives (42.9 mg/g of extract). In this study hydrophilic and lipophilic antioxidant assays were performed together for the first time in P. americana by-products, and although kernels showed a great antioxidant potential (EC 50 values ranging from 18.1 to 276 µg/mL), peels presented the highest potential (EC 50 ranging from 11.7 to 152 µg/mL), mainly due to the presence of phenolic compounds, and an overall better performance in the antibacterial assays. Further studies needs to be conducted to better understand the correlation between the presence of phenolic compounds and bioactivities, however, the main objective is to implement these biocompounds in different products and industries, due to results obtained, P. americana peels could be a great alternative in the substitution of synthetic antioxidants.
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spelling Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidantsHass avocadoPolyphenolsFlavonoidsAntimicrobial activityAntioxidant capacityHPLC-DAD/ESI–MSAvocado (Persea americana Mill.) is a worldwide consumed fruit, with great interest for cosmetic and pharmaceutical industries; however, 30% of avocado fruits are bio-wastes (peels and kernels), converting them into a potential source of bioactive compounds, such as phenolic compounds. Therefore, the hydroethanolic extracts of peels and kernels of Persea america Mill. var. Hass were analysed regarding their individual phenolic profile by HPLC-DAD/ESI–MS and correlated with their antioxidant, antimicrobial and cytotoxic activities. Avocado by-products presented a very distinct phenolic profile, presenting higher concentration in peels (227.9 mg/g of extract for total phenolic content), mainly in (epi)catechin derivatives (175 mg/g of extract), followed by chlorogenic derivatives (42.9 mg/g of extract). In this study hydrophilic and lipophilic antioxidant assays were performed together for the first time in P. americana by-products, and although kernels showed a great antioxidant potential (EC 50 values ranging from 18.1 to 276 µg/mL), peels presented the highest potential (EC 50 ranging from 11.7 to 152 µg/mL), mainly due to the presence of phenolic compounds, and an overall better performance in the antibacterial assays. Further studies needs to be conducted to better understand the correlation between the presence of phenolic compounds and bioactivities, however, the main objective is to implement these biocompounds in different products and industries, due to results obtained, P. americana peels could be a great alternative in the substitution of synthetic antioxidants.The authors are grateful to the Foundation for Science and Technology(FCT, Portugal) and FEDER under Program PT2020 for financial support to CIMO (UID/AGR/00690/2013) and L. Barros contract. The authors would like to thank the Interreg España-Portugal for financial support through the project 0377_Iberphenol_6_E. B. Melgar thanks CONACyT for his grant (No. 329930). The authors are also grateful to the Serbian Ministry of Education, Science and Technological Development, grant number 173032 for financial support.Biblioteca Digital do IPBMelgar Castañeda, BrunoDias, Maria InêsĆirić, AnaSoković, MarinaGarcia-Castello, Esperanza M.Rodriguez-Lopez, Antonio D.Barros, LillianFerreira, Isabel C.F.R.2018-01-25T10:00:00Z20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10198/15055engMelgar, Bruno; Dias, Maria Inês; Ćirić, Ana; Soković, Marina; Garcia-Castello, Esperanza M.; Rodriguez-Lopez, Antonio D.; Barros, Lillian; Ferreira, Isabel C.R.F. (2018). Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants. Industrial Crops & Products. ISSN 0926-6690. 111, p. 212-2180926-669010.1016/j.indcrop.2017.10.024info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-21T10:35:33Zoai:bibliotecadigital.ipb.pt:10198/15055Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:04:51.290910Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
title Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
spellingShingle Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
Melgar Castañeda, Bruno
Hass avocado
Polyphenols
Flavonoids
Antimicrobial activity
Antioxidant capacity
HPLC-DAD/ESI–MS
title_short Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
title_full Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
title_fullStr Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
title_full_unstemmed Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
title_sort Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants
author Melgar Castañeda, Bruno
author_facet Melgar Castañeda, Bruno
Dias, Maria Inês
Ćirić, Ana
Soković, Marina
Garcia-Castello, Esperanza M.
Rodriguez-Lopez, Antonio D.
Barros, Lillian
Ferreira, Isabel C.F.R.
author_role author
author2 Dias, Maria Inês
Ćirić, Ana
Soković, Marina
Garcia-Castello, Esperanza M.
Rodriguez-Lopez, Antonio D.
Barros, Lillian
Ferreira, Isabel C.F.R.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Biblioteca Digital do IPB
dc.contributor.author.fl_str_mv Melgar Castañeda, Bruno
Dias, Maria Inês
Ćirić, Ana
Soković, Marina
Garcia-Castello, Esperanza M.
Rodriguez-Lopez, Antonio D.
Barros, Lillian
Ferreira, Isabel C.F.R.
dc.subject.por.fl_str_mv Hass avocado
Polyphenols
Flavonoids
Antimicrobial activity
Antioxidant capacity
HPLC-DAD/ESI–MS
topic Hass avocado
Polyphenols
Flavonoids
Antimicrobial activity
Antioxidant capacity
HPLC-DAD/ESI–MS
description Avocado (Persea americana Mill.) is a worldwide consumed fruit, with great interest for cosmetic and pharmaceutical industries; however, 30% of avocado fruits are bio-wastes (peels and kernels), converting them into a potential source of bioactive compounds, such as phenolic compounds. Therefore, the hydroethanolic extracts of peels and kernels of Persea america Mill. var. Hass were analysed regarding their individual phenolic profile by HPLC-DAD/ESI–MS and correlated with their antioxidant, antimicrobial and cytotoxic activities. Avocado by-products presented a very distinct phenolic profile, presenting higher concentration in peels (227.9 mg/g of extract for total phenolic content), mainly in (epi)catechin derivatives (175 mg/g of extract), followed by chlorogenic derivatives (42.9 mg/g of extract). In this study hydrophilic and lipophilic antioxidant assays were performed together for the first time in P. americana by-products, and although kernels showed a great antioxidant potential (EC 50 values ranging from 18.1 to 276 µg/mL), peels presented the highest potential (EC 50 ranging from 11.7 to 152 µg/mL), mainly due to the presence of phenolic compounds, and an overall better performance in the antibacterial assays. Further studies needs to be conducted to better understand the correlation between the presence of phenolic compounds and bioactivities, however, the main objective is to implement these biocompounds in different products and industries, due to results obtained, P. americana peels could be a great alternative in the substitution of synthetic antioxidants.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-25T10:00:00Z
2018
2018-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10198/15055
url http://hdl.handle.net/10198/15055
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Melgar, Bruno; Dias, Maria Inês; Ćirić, Ana; Soković, Marina; Garcia-Castello, Esperanza M.; Rodriguez-Lopez, Antonio D.; Barros, Lillian; Ferreira, Isabel C.R.F. (2018). Bioactive characterization of Persea americana Mill. by-products: A rich source of inherent antioxidants. Industrial Crops & Products. ISSN 0926-6690. 111, p. 212-218
0926-6690
10.1016/j.indcrop.2017.10.024
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
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