Milk fat components with potential anticancer activity - a review

Detalhes bibliográficos
Autor(a) principal: Rodríguez-Alcalá, Luis M.
Data de Publicação: 2017
Outros Autores: Castro-Gómez, M. Pilar, Pimentel, Lígia L., Fontecha, Javier
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.14/25716
Resumo: During many years, the milk fat has been unfairly undervalued due to its association with higher levels of cardiovascular diseases, dyslipidaemia or obesity, among others. However, currently, this relationship is being re-evaluated because some of the dairy lipid components have been attributed potential health benefits. Due to this, and based on the increasing incidence of cancer in our society, this review work aims to discuss the state of the art concerning scientific evidence of milk lipid components and reported anticancer properties. Results from the in vitro and in vivo experiments suggest that specific fatty acids (FA) (as butyric acid and conjugated linoleic acid (CLA), among others), phospholipids and sphin-golipids from milk globule membrane are potential anticarcinogenic agents. However, their mechanism of action remains still unclear due to limited and inconsistent findings in human studies.
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spelling Milk fat components with potential anticancer activity - a reviewDuring many years, the milk fat has been unfairly undervalued due to its association with higher levels of cardiovascular diseases, dyslipidaemia or obesity, among others. However, currently, this relationship is being re-evaluated because some of the dairy lipid components have been attributed potential health benefits. Due to this, and based on the increasing incidence of cancer in our society, this review work aims to discuss the state of the art concerning scientific evidence of milk lipid components and reported anticancer properties. Results from the in vitro and in vivo experiments suggest that specific fatty acids (FA) (as butyric acid and conjugated linoleic acid (CLA), among others), phospholipids and sphin-golipids from milk globule membrane are potential anticarcinogenic agents. However, their mechanism of action remains still unclear due to limited and inconsistent findings in human studies.Portland PressVeritati - Repositório Institucional da Universidade Católica PortuguesaRodríguez-Alcalá, Luis M.Castro-Gómez, M. PilarPimentel, Lígia L.Fontecha, Javier2018-09-19T15:39:18Z20172017-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/25716engRodríguez-Alcalá, L.M., Castro-Gómez, M.P., Pimentel, L.L., Fontecha, J. (2017). Milk fat components with potential anticancer activity - a review. Bioscience Reports, 37(6), BSR201707050144-846310.1042/BSR201707051573-493585039869405PMC637225629026007000415833300001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-09-12T01:38:38Zoai:repositorio.ucp.pt:10400.14/25716Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:20:29.847717Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Milk fat components with potential anticancer activity - a review
title Milk fat components with potential anticancer activity - a review
spellingShingle Milk fat components with potential anticancer activity - a review
Rodríguez-Alcalá, Luis M.
title_short Milk fat components with potential anticancer activity - a review
title_full Milk fat components with potential anticancer activity - a review
title_fullStr Milk fat components with potential anticancer activity - a review
title_full_unstemmed Milk fat components with potential anticancer activity - a review
title_sort Milk fat components with potential anticancer activity - a review
author Rodríguez-Alcalá, Luis M.
author_facet Rodríguez-Alcalá, Luis M.
Castro-Gómez, M. Pilar
Pimentel, Lígia L.
Fontecha, Javier
author_role author
author2 Castro-Gómez, M. Pilar
Pimentel, Lígia L.
Fontecha, Javier
author2_role author
author
author
dc.contributor.none.fl_str_mv Veritati - Repositório Institucional da Universidade Católica Portuguesa
dc.contributor.author.fl_str_mv Rodríguez-Alcalá, Luis M.
Castro-Gómez, M. Pilar
Pimentel, Lígia L.
Fontecha, Javier
description During many years, the milk fat has been unfairly undervalued due to its association with higher levels of cardiovascular diseases, dyslipidaemia or obesity, among others. However, currently, this relationship is being re-evaluated because some of the dairy lipid components have been attributed potential health benefits. Due to this, and based on the increasing incidence of cancer in our society, this review work aims to discuss the state of the art concerning scientific evidence of milk lipid components and reported anticancer properties. Results from the in vitro and in vivo experiments suggest that specific fatty acids (FA) (as butyric acid and conjugated linoleic acid (CLA), among others), phospholipids and sphin-golipids from milk globule membrane are potential anticarcinogenic agents. However, their mechanism of action remains still unclear due to limited and inconsistent findings in human studies.
publishDate 2017
dc.date.none.fl_str_mv 2017
2017-01-01T00:00:00Z
2018-09-19T15:39:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.14/25716
url http://hdl.handle.net/10400.14/25716
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rodríguez-Alcalá, L.M., Castro-Gómez, M.P., Pimentel, L.L., Fontecha, J. (2017). Milk fat components with potential anticancer activity - a review. Bioscience Reports, 37(6), BSR20170705
0144-8463
10.1042/BSR20170705
1573-4935
85039869405
PMC6372256
29026007
000415833300001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Portland Press
publisher.none.fl_str_mv Portland Press
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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