Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats

Detalhes bibliográficos
Autor(a) principal: Martins,Francielle
Data de Publicação: 2015
Outros Autores: Rennó,Ana Cláudia Muniz, Oliveira,Flávia de, Minatel,Natália Peruchi, Bortolin,Jeferson André, Quintana,Hananiah Tardivo, Aveiro,Mariana Chaves
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Acta Cirúrgica Brasileira (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000200094
Resumo: PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression.
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spelling Low-level laser therapy modulates musculoskeletal loss in a skin burn model in ratsBurnsLaser Therapy, Low-LevelMyoD ProteinRats PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression. Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia2015-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000200094Acta Cirúrgica Brasileira v.30 n.2 2015reponame:Acta Cirúrgica Brasileira (Online)instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)instacron:SBDPC10.1590/S0102-86502015002000002info:eu-repo/semantics/openAccessMartins,FrancielleRennó,Ana Cláudia MunizOliveira,Flávia deMinatel,Natália PeruchiBortolin,Jeferson AndréQuintana,Hananiah TardivoAveiro,Mariana Chaveseng2015-07-02T00:00:00Zoai:scielo:S0102-86502015000200094Revistahttps://www.bvs-vet.org.br/vetindex/periodicos/acta-cirurgica-brasileira/https://old.scielo.br/oai/scielo-oai.php||sgolden@terra.com.br0102-86501678-2674opendoar:2015-07-02T00:00Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)false
dc.title.none.fl_str_mv Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
title Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
spellingShingle Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
Martins,Francielle
Burns
Laser Therapy, Low-Level
MyoD Protein
Rats
title_short Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
title_full Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
title_fullStr Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
title_full_unstemmed Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
title_sort Low-level laser therapy modulates musculoskeletal loss in a skin burn model in rats
author Martins,Francielle
author_facet Martins,Francielle
Rennó,Ana Cláudia Muniz
Oliveira,Flávia de
Minatel,Natália Peruchi
Bortolin,Jeferson André
Quintana,Hananiah Tardivo
Aveiro,Mariana Chaves
author_role author
author2 Rennó,Ana Cláudia Muniz
Oliveira,Flávia de
Minatel,Natália Peruchi
Bortolin,Jeferson André
Quintana,Hananiah Tardivo
Aveiro,Mariana Chaves
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Martins,Francielle
Rennó,Ana Cláudia Muniz
Oliveira,Flávia de
Minatel,Natália Peruchi
Bortolin,Jeferson André
Quintana,Hananiah Tardivo
Aveiro,Mariana Chaves
dc.subject.por.fl_str_mv Burns
Laser Therapy, Low-Level
MyoD Protein
Rats
topic Burns
Laser Therapy, Low-Level
MyoD Protein
Rats
description PURPOSE: To investigate the effectiveness of low-level laser therapy (LLLT) on gastrocnemius muscle morphology and Myod imunoexpression in a model of dorsal burn in rats. METHODS: Sixteen male Wistar rats were distributed into two groups: control group (CG): rats submitted to scald burn injury without treatment and laser treated group (LG): rats submitted to scald burn injury and treated with laser therapy. Fourteen days post-surgery, gastrocnemius muscle was evaluated being the specimens stained with HE and morphometric data was evaluated. MyoD expression was assessed by immunohistochemistry. RESULTS: The results showed that laser treated animals presented more organized tissue morphology compared to the non-treated animals, with a higher number of nucleus in the fibers. Also, the cross sectional area of the fibers and the MyoD immunoexpression in the laser treated groups was higher. CONCLUSION: Low-level laser therapy had positive effects on gastrocnemius muscle, improving tissue muscle morphology, increasing cross sectional area and MyoD immunoexpression.
publishDate 2015
dc.date.none.fl_str_mv 2015-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000200094
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000200094
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0102-86502015002000002
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publisher.none.fl_str_mv Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
dc.source.none.fl_str_mv Acta Cirúrgica Brasileira v.30 n.2 2015
reponame:Acta Cirúrgica Brasileira (Online)
instname:Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron:SBDPC
instname_str Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
instacron_str SBDPC
institution SBDPC
reponame_str Acta Cirúrgica Brasileira (Online)
collection Acta Cirúrgica Brasileira (Online)
repository.name.fl_str_mv Acta Cirúrgica Brasileira (Online) - Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC)
repository.mail.fl_str_mv ||sgolden@terra.com.br
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