Uneventful benznidazole treatment of acute Chagas disease during pregnancy: a case report

• Autor(a) principal: Corrêa,Valeria Rita
• Data de Publicação: 2014
• Outros Autores: Barbosa,Fernanda Gama, Melo Junior,Claudimar Américo de, Castro,Luis Fernando D'Albuquerque e, Andrade Junior,Heitor Franco de, Nascimento,Nanci
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Revista da Sociedade Brasileira de Medicina Tropical
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822014000300397
• topic: Acute Chagas disease; Benznidazole; Pregnancy

This report describes the case of a patient with acute Chagas disease in Tocantins, Brazil, who was unaware of her pregnancy during benznidazole treatment. She presented with impaired cardiac function during the acute phase (pericarditis and incomplete right bundle-branch block) that resolved favorably after benznidazole therapy. Serological results also became negative, as determined by hemagglutination assays, enzyme-linked immunosorbent assays, and immunofluorescence assays. The child was born without sequelae and showed no evidence of congenital Trypanosoma cruzi infection at birth or 24 days later.