Solitary fibrous tumor of the kidney: a report of two cases

• Autor(a) principal: Oliveira,Rui Pedro Caetano M.
• Data de Publicação: 2019
• Outros Autores: Silva,Edgar Miguel C. L. T, Marinho,Carol dos Anjos, Lopez,José Ignacio, Castro,Lígia Romana O. A. P.
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Jornal Brasileiro de Patologia e Medicina Laboratorial (Online)
• Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442019000100118
• topic: solitary fibrous tumors; kidney neoplasms; immunohistochemistry

ABSTRACT Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm, composed of monotonous spindle cells, intermingled with collagen fibers. Kidney location is sporadic, with few reports in literature. We present two cases of 40- and 48-year-old males, one with incidental detection of a peripheral mass; another with hilar lesion perceived following investigation of hematuria. Both revealed a spindle-cell proliferation, without mitosis and necrosis. Immunohistochemical studies: positivity for CD34, CD99 and B-cell lymphoma 2 (Bcl-2). No sign of disease were evident nine and five months after surgery, respectively. SFT is mostly benign, but can show malignant behavior. Morphologic and immunohistochemical characteristics are essential for diagnosis.