Large solitary fibrous tumor of the oral cavity - Report of a case

• Autor(a) principal: Oliveira, Denise Hélen Imaculada Pereira de
• Data de Publicação: 2014
• Outros Autores: Albuquerque, Assis Filipe Medeiros, Barreto, Matheus Dantas de Araújo, Nonaka, Cassiano Francisco Weege, Silva, José Sandro Pereira da, Germano, Adriano Rocha, Queiroz, Lélia Maria Guedes
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFRN
• Texto Completo: https://repositorio.ufrn.br/jspui/handle/123456789/23906; https://doi.org/10.1016/j.prp.2014.09.018
• topic: Solitary fibrous tumor; Oral cavity; Differential diagnosis; Immunohistochemistry; CD34

The solitary fibrous tumor (SFT) is a rare soft tissue tumor with a substantially benign clinical behavior. The SFT of the oral cavity is a very uncommon entity. It is also of complicated diagnosis because of its extensive morphologic diversity and because of its similarity to many mesenchymal tumors. A 44-year-old man was referred for management of an asymptomatic lesion in the left buccal mucosa, which had been identified 10 years earlier. Intra-oral examination revealed a well-demarcated, fibroelastic, rounded exophytic mass located in the left buccal mucosa. The mass was covered with a non-ulcerated mucosa of normal color and measured approximately 4.0 cm in diameter. Histopathological examination showed proliferation of spindle-shaped cells arranged in fascicles and in a patternless pattern, highly vascularized, with focal staghorn vessels. Immunohistochemical analysis revealed diffuse positivity for CD34 and focal positivity for Bcl-2. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from other spindle cell neoplasms.