Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Jornal de Pediatria (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572019000200238 |
Resumo: | Abstract Objective: To investigate ApoB/ApoA1 ratio and its association with cardiovascular risk factors in children. Methods: Cross-sectional study with 258 children aged 8 and 9 years old, enrolled in all urban schools in the city of Viçosa-MG. Anthropometric and body composition assessment, as well as biochemical profile of the children was performed. Socioeconomic variables and sedentary lifestyle were evaluated through a semi-structured questionnaire. Results: Many children had excess weight (35.2%), abdominal adiposity (10.5%), and body fat (15.6%), as well as increased ApoB/ApoA1 ratio (14.7%), total cholesterol (51.8%), and triglycerides (19.8%). Children with excess weight and total and central fat had a higher prevalence of having a higher ApoB/ApoA1 ratio, as well as those with atherogenic lipid profile (increased LDL-c and triglycerides and low HDL-c). A direct association was found between the number of cardiovascular risk factors and the ApoB/ApoA1 ratio (p = 0.001), regardless of age and income. Conclusion: The increased ApoB/ApoA1 ratio was associated with excess weight, body adiposity (total and central), and altered lipid profile in children. Children with a higher number of cardiovascular risk factors had higher ApoB/ApoA1 ratio, in both genders. |
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Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in childrenChildrenDyslipidemiasAdiposityApolipoproteinsAbstract Objective: To investigate ApoB/ApoA1 ratio and its association with cardiovascular risk factors in children. Methods: Cross-sectional study with 258 children aged 8 and 9 years old, enrolled in all urban schools in the city of Viçosa-MG. Anthropometric and body composition assessment, as well as biochemical profile of the children was performed. Socioeconomic variables and sedentary lifestyle were evaluated through a semi-structured questionnaire. Results: Many children had excess weight (35.2%), abdominal adiposity (10.5%), and body fat (15.6%), as well as increased ApoB/ApoA1 ratio (14.7%), total cholesterol (51.8%), and triglycerides (19.8%). Children with excess weight and total and central fat had a higher prevalence of having a higher ApoB/ApoA1 ratio, as well as those with atherogenic lipid profile (increased LDL-c and triglycerides and low HDL-c). A direct association was found between the number of cardiovascular risk factors and the ApoB/ApoA1 ratio (p = 0.001), regardless of age and income. Conclusion: The increased ApoB/ApoA1 ratio was associated with excess weight, body adiposity (total and central), and altered lipid profile in children. Children with a higher number of cardiovascular risk factors had higher ApoB/ApoA1 ratio, in both genders.Sociedade Brasileira de Pediatria2019-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572019000200238Jornal de Pediatria v.95 n.2 2019reponame:Jornal de Pediatria (Online)instname:Sociedade Brasileira de Pediatria (SBP)instacron:SBPE10.1016/j.jped.2017.12.008info:eu-repo/semantics/openAccessCastro,Ana Paula PereiraHermsdorff,Helen Hermana MirandaMilagres,Luana CupertinoAlbuquerque,Fernanda Martins deFilgueiras,Mariana de SantisRocha,Naruna PereiraNovaes,Juliana Farias deeng2019-04-08T00:00:00Zoai:scielo:S0021-75572019000200238Revistahttp://www.jped.com.br/https://old.scielo.br/oai/scielo-oai.php||jped@jped.com.br1678-47820021-7557opendoar:2019-04-08T00:00Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP)false |
dc.title.none.fl_str_mv |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
title |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
spellingShingle |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children Castro,Ana Paula Pereira Children Dyslipidemias Adiposity Apolipoproteins |
title_short |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
title_full |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
title_fullStr |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
title_full_unstemmed |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
title_sort |
Increased ApoB/ApoA1 ratio is associated with excess weight, body adiposity, and altered lipid profile in children |
author |
Castro,Ana Paula Pereira |
author_facet |
Castro,Ana Paula Pereira Hermsdorff,Helen Hermana Miranda Milagres,Luana Cupertino Albuquerque,Fernanda Martins de Filgueiras,Mariana de Santis Rocha,Naruna Pereira Novaes,Juliana Farias de |
author_role |
author |
author2 |
Hermsdorff,Helen Hermana Miranda Milagres,Luana Cupertino Albuquerque,Fernanda Martins de Filgueiras,Mariana de Santis Rocha,Naruna Pereira Novaes,Juliana Farias de |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Castro,Ana Paula Pereira Hermsdorff,Helen Hermana Miranda Milagres,Luana Cupertino Albuquerque,Fernanda Martins de Filgueiras,Mariana de Santis Rocha,Naruna Pereira Novaes,Juliana Farias de |
dc.subject.por.fl_str_mv |
Children Dyslipidemias Adiposity Apolipoproteins |
topic |
Children Dyslipidemias Adiposity Apolipoproteins |
description |
Abstract Objective: To investigate ApoB/ApoA1 ratio and its association with cardiovascular risk factors in children. Methods: Cross-sectional study with 258 children aged 8 and 9 years old, enrolled in all urban schools in the city of Viçosa-MG. Anthropometric and body composition assessment, as well as biochemical profile of the children was performed. Socioeconomic variables and sedentary lifestyle were evaluated through a semi-structured questionnaire. Results: Many children had excess weight (35.2%), abdominal adiposity (10.5%), and body fat (15.6%), as well as increased ApoB/ApoA1 ratio (14.7%), total cholesterol (51.8%), and triglycerides (19.8%). Children with excess weight and total and central fat had a higher prevalence of having a higher ApoB/ApoA1 ratio, as well as those with atherogenic lipid profile (increased LDL-c and triglycerides and low HDL-c). A direct association was found between the number of cardiovascular risk factors and the ApoB/ApoA1 ratio (p = 0.001), regardless of age and income. Conclusion: The increased ApoB/ApoA1 ratio was associated with excess weight, body adiposity (total and central), and altered lipid profile in children. Children with a higher number of cardiovascular risk factors had higher ApoB/ApoA1 ratio, in both genders. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572019000200238 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0021-75572019000200238 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1016/j.jped.2017.12.008 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
publisher.none.fl_str_mv |
Sociedade Brasileira de Pediatria |
dc.source.none.fl_str_mv |
Jornal de Pediatria v.95 n.2 2019 reponame:Jornal de Pediatria (Online) instname:Sociedade Brasileira de Pediatria (SBP) instacron:SBPE |
instname_str |
Sociedade Brasileira de Pediatria (SBP) |
instacron_str |
SBPE |
institution |
SBPE |
reponame_str |
Jornal de Pediatria (Online) |
collection |
Jornal de Pediatria (Online) |
repository.name.fl_str_mv |
Jornal de Pediatria (Online) - Sociedade Brasileira de Pediatria (SBP) |
repository.mail.fl_str_mv |
||jped@jped.com.br |
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1752122321806557184 |