A new neolignan and antioxidant phenols from Nectandra grandiflora

Detalhes bibliográficos
Autor(a) principal: Ribeiro,Alan B.
Data de Publicação: 2005
Outros Autores: Bolzani,Vanderlan da S., Yoshida,Massayoshi, Santos,Leonardo S., Eberlin,Marcos N., Silva,Dulce H. S.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Chemical Society (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000400005
Resumo: The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards b-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (DA 32, 16 and 73% at 50 µmol L-1) and were compared to commercial antioxidants rutin (81% at 50 µmol L-1) and BHT (9% at 50 µmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2'-oxo-piperol B were obtained and characterized by spectrometric methods.
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spelling A new neolignan and antioxidant phenols from Nectandra grandifloraNectandra grandifloraLauraceaeneolignanflavonoidradical scavenging activityantioxidantThe EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards b-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (DA 32, 16 and 73% at 50 µmol L-1) and were compared to commercial antioxidants rutin (81% at 50 µmol L-1) and BHT (9% at 50 µmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2'-oxo-piperol B were obtained and characterized by spectrometric methods.Sociedade Brasileira de Química2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000400005Journal of the Brazilian Chemical Society v.16 n.3b 2005reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532005000400005info:eu-repo/semantics/openAccessRibeiro,Alan B.Bolzani,Vanderlan da S.Yoshida,MassayoshiSantos,Leonardo S.Eberlin,Marcos N.Silva,Dulce H. S.eng2005-08-09T00:00:00Zoai:scielo:S0103-50532005000400005Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2005-08-09T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false
dc.title.none.fl_str_mv A new neolignan and antioxidant phenols from Nectandra grandiflora
title A new neolignan and antioxidant phenols from Nectandra grandiflora
spellingShingle A new neolignan and antioxidant phenols from Nectandra grandiflora
Ribeiro,Alan B.
Nectandra grandiflora
Lauraceae
neolignan
flavonoid
radical scavenging activity
antioxidant
title_short A new neolignan and antioxidant phenols from Nectandra grandiflora
title_full A new neolignan and antioxidant phenols from Nectandra grandiflora
title_fullStr A new neolignan and antioxidant phenols from Nectandra grandiflora
title_full_unstemmed A new neolignan and antioxidant phenols from Nectandra grandiflora
title_sort A new neolignan and antioxidant phenols from Nectandra grandiflora
author Ribeiro,Alan B.
author_facet Ribeiro,Alan B.
Bolzani,Vanderlan da S.
Yoshida,Massayoshi
Santos,Leonardo S.
Eberlin,Marcos N.
Silva,Dulce H. S.
author_role author
author2 Bolzani,Vanderlan da S.
Yoshida,Massayoshi
Santos,Leonardo S.
Eberlin,Marcos N.
Silva,Dulce H. S.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Ribeiro,Alan B.
Bolzani,Vanderlan da S.
Yoshida,Massayoshi
Santos,Leonardo S.
Eberlin,Marcos N.
Silva,Dulce H. S.
dc.subject.por.fl_str_mv Nectandra grandiflora
Lauraceae
neolignan
flavonoid
radical scavenging activity
antioxidant
topic Nectandra grandiflora
Lauraceae
neolignan
flavonoid
radical scavenging activity
antioxidant
description The EtOH crude extract from the leaves of Nectandra grandiflora collected in the Atlantic Forest, Brazil, showed antioxidant activity towards b-carotene in a TLC assay. The bioassay-guided fractionation led to the isolation of protocatechuic acid and two flavonol glycosides: afzelin and quercetrin, which showed free radical scavenging activity towards DPPH (DA 32, 16 and 73% at 50 µmol L-1) and were compared to commercial antioxidants rutin (81% at 50 µmol L-1) and BHT (9% at 50 µmol L-1), used as standard compounds. Additionally, three inactive neolignans, including the new bicycle[3.2.1]octane neolignan 2'-oxo-piperol B were obtained and characterized by spectrometric methods.
publishDate 2005
dc.date.none.fl_str_mv 2005-06-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000400005
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532005000400005
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0103-50532005000400005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Brasileira de Química
publisher.none.fl_str_mv Sociedade Brasileira de Química
dc.source.none.fl_str_mv Journal of the Brazilian Chemical Society v.16 n.3b 2005
reponame:Journal of the Brazilian Chemical Society (Online)
instname:Sociedade Brasileira de Química (SBQ)
instacron:SBQ
instname_str Sociedade Brasileira de Química (SBQ)
instacron_str SBQ
institution SBQ
reponame_str Journal of the Brazilian Chemical Society (Online)
collection Journal of the Brazilian Chemical Society (Online)
repository.name.fl_str_mv Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)
repository.mail.fl_str_mv ||office@jbcs.sbq.org.br
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