Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups
Autor(a) principal: | |
---|---|
Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Chemical Society (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000500003 |
Resumo: | The transmetalation between boron and zinc is of great importance for application in organic synthesis, since it allows the formation of new carbon-carbon bonds between organometallic units and electrophiles. The direct arylation of aldehydes or more scarcely ketones, in a catalytic, enantioselective manner using chiral catalysts has been described recently. The enantiomerically enriched diarylmethanols obtained in these reactions are valuable precursors for important bioactive molecules. This review provides a synopsis of this ever-growing field and highlights some of the challenges that still remain. |
id |
SBQ-2_dfe60299da1d7b4e19ef133480895a3a |
---|---|
oai_identifier_str |
oai:scielo:S0103-50532008000500003 |
network_acronym_str |
SBQ-2 |
network_name_str |
Journal of the Brazilian Chemical Society (Online) |
repository_id_str |
|
spelling |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groupsdiarylmethanolboronic acidboron-to-zinc exchangeasymmetric catalysisThe transmetalation between boron and zinc is of great importance for application in organic synthesis, since it allows the formation of new carbon-carbon bonds between organometallic units and electrophiles. The direct arylation of aldehydes or more scarcely ketones, in a catalytic, enantioselective manner using chiral catalysts has been described recently. The enantiomerically enriched diarylmethanols obtained in these reactions are valuable precursors for important bioactive molecules. This review provides a synopsis of this ever-growing field and highlights some of the challenges that still remain.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000500003Journal of the Brazilian Chemical Society v.19 n.5 2008reponame:Journal of the Brazilian Chemical Society (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0103-50532008000500003info:eu-repo/semantics/openAccessPaixão,Márcio W.Braga,Antonio L.Lüdtke,Diogo S.eng2008-08-05T00:00:00Zoai:scielo:S0103-50532008000500003Revistahttp://jbcs.sbq.org.brONGhttps://old.scielo.br/oai/scielo-oai.php||office@jbcs.sbq.org.br1678-47900103-5053opendoar:2008-08-05T00:00Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
title |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
spellingShingle |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups Paixão,Márcio W. diarylmethanol boronic acid boron-to-zinc exchange asymmetric catalysis |
title_short |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
title_full |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
title_fullStr |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
title_full_unstemmed |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
title_sort |
Catalytic enantioselective arylations: boron to zinc exchange as a powerful tool for the generation of transferable aryl groups |
author |
Paixão,Márcio W. |
author_facet |
Paixão,Márcio W. Braga,Antonio L. Lüdtke,Diogo S. |
author_role |
author |
author2 |
Braga,Antonio L. Lüdtke,Diogo S. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Paixão,Márcio W. Braga,Antonio L. Lüdtke,Diogo S. |
dc.subject.por.fl_str_mv |
diarylmethanol boronic acid boron-to-zinc exchange asymmetric catalysis |
topic |
diarylmethanol boronic acid boron-to-zinc exchange asymmetric catalysis |
description |
The transmetalation between boron and zinc is of great importance for application in organic synthesis, since it allows the formation of new carbon-carbon bonds between organometallic units and electrophiles. The direct arylation of aldehydes or more scarcely ketones, in a catalytic, enantioselective manner using chiral catalysts has been described recently. The enantiomerically enriched diarylmethanols obtained in these reactions are valuable precursors for important bioactive molecules. This review provides a synopsis of this ever-growing field and highlights some of the challenges that still remain. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000500003 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532008000500003 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0103-50532008000500003 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Journal of the Brazilian Chemical Society v.19 n.5 2008 reponame:Journal of the Brazilian Chemical Society (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Journal of the Brazilian Chemical Society (Online) |
collection |
Journal of the Brazilian Chemical Society (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Chemical Society (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
||office@jbcs.sbq.org.br |
_version_ |
1750318168986877952 |