A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina
Main Author: | |
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Publication Date: | 2008 |
Other Authors: | , , , , , , , , , , , , , , , , , |
Format: | Article |
Language: | eng |
Source: | Química Nova (Online) |
Download full: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500030 |
Summary: | Extracts obtained from 57 marine-derived fungal strains were analyzed by HPLC-PDA, TLC and ¹H NMR. The analyses showed that the growth conditions affected the chemical profile of crude extracts. Furthermore, the majority of fungal strains which produced either bioactive of chemically distinctive crude extracts have been isolated from sediments or marine algae. The chemical investigation of the antimycobacterial and cytotoxic crude extract obtained from two strains of the fungus Beauveria felina have yielded cyclodepsipeptides related to destruxins. The present approach constitutes a valuable tool for the selection of fungal strains that produce chemically interesting or biologically active secondary metabolites. |
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A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felinamarine-derived fungiscreeningBeauveria felinaExtracts obtained from 57 marine-derived fungal strains were analyzed by HPLC-PDA, TLC and ¹H NMR. The analyses showed that the growth conditions affected the chemical profile of crude extracts. Furthermore, the majority of fungal strains which produced either bioactive of chemically distinctive crude extracts have been isolated from sediments or marine algae. The chemical investigation of the antimycobacterial and cytotoxic crude extract obtained from two strains of the fungus Beauveria felina have yielded cyclodepsipeptides related to destruxins. The present approach constitutes a valuable tool for the selection of fungal strains that produce chemically interesting or biologically active secondary metabolites.Sociedade Brasileira de Química2008-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500030Química Nova v.31 n.5 2008reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.1590/S0100-40422008000500030info:eu-repo/semantics/openAccessVita-Marques,Aline Maria deLira,Simone P.Berlinck,Roberto G. S.Seleghim,Mirna H. R.Sponchiado,Sandra R. P.Tauk-Tornisielo,Sâmia M.Barata,MargaridaPessoa,ClaudiaMoraes,Manoel O. deCavalcanti,Bruno CoêlhoNascimento,Gislene G. F.Souza,Ana O. deGaletti,Fabio C. S.Silva,Célio L.Silva,MarcioPimenta,Eli F.Thiemann,OtavioPassarini,Michel R. Z.Sette,Lara D.eng2008-09-12T00:00:00Zoai:scielo:S0100-40422008000500030Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2008-09-12T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
title |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
spellingShingle |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina Vita-Marques,Aline Maria de marine-derived fungi screening Beauveria felina |
title_short |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
title_full |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
title_fullStr |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
title_full_unstemmed |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
title_sort |
A multi-screening approach for marine-derived fungal metabolites and the isolation of cyclodepsipeptides from Beauveria felina |
author |
Vita-Marques,Aline Maria de |
author_facet |
Vita-Marques,Aline Maria de Lira,Simone P. Berlinck,Roberto G. S. Seleghim,Mirna H. R. Sponchiado,Sandra R. P. Tauk-Tornisielo,Sâmia M. Barata,Margarida Pessoa,Claudia Moraes,Manoel O. de Cavalcanti,Bruno Coêlho Nascimento,Gislene G. F. Souza,Ana O. de Galetti,Fabio C. S. Silva,Célio L. Silva,Marcio Pimenta,Eli F. Thiemann,Otavio Passarini,Michel R. Z. Sette,Lara D. |
author_role |
author |
author2 |
Lira,Simone P. Berlinck,Roberto G. S. Seleghim,Mirna H. R. Sponchiado,Sandra R. P. Tauk-Tornisielo,Sâmia M. Barata,Margarida Pessoa,Claudia Moraes,Manoel O. de Cavalcanti,Bruno Coêlho Nascimento,Gislene G. F. Souza,Ana O. de Galetti,Fabio C. S. Silva,Célio L. Silva,Marcio Pimenta,Eli F. Thiemann,Otavio Passarini,Michel R. Z. Sette,Lara D. |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Vita-Marques,Aline Maria de Lira,Simone P. Berlinck,Roberto G. S. Seleghim,Mirna H. R. Sponchiado,Sandra R. P. Tauk-Tornisielo,Sâmia M. Barata,Margarida Pessoa,Claudia Moraes,Manoel O. de Cavalcanti,Bruno Coêlho Nascimento,Gislene G. F. Souza,Ana O. de Galetti,Fabio C. S. Silva,Célio L. Silva,Marcio Pimenta,Eli F. Thiemann,Otavio Passarini,Michel R. Z. Sette,Lara D. |
dc.subject.por.fl_str_mv |
marine-derived fungi screening Beauveria felina |
topic |
marine-derived fungi screening Beauveria felina |
description |
Extracts obtained from 57 marine-derived fungal strains were analyzed by HPLC-PDA, TLC and ¹H NMR. The analyses showed that the growth conditions affected the chemical profile of crude extracts. Furthermore, the majority of fungal strains which produced either bioactive of chemically distinctive crude extracts have been isolated from sediments or marine algae. The chemical investigation of the antimycobacterial and cytotoxic crude extract obtained from two strains of the fungus Beauveria felina have yielded cyclodepsipeptides related to destruxins. The present approach constitutes a valuable tool for the selection of fungal strains that produce chemically interesting or biologically active secondary metabolites. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500030 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422008000500030 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-40422008000500030 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.31 n.5 2008 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318107664056320 |