ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Química Nova (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021001001245 |
Resumo: | The electrospinning has been widely used in tissue engineering for the preparation of wound dressing with the most varied polymers and drugs. Considering that propolis has antimicrobial and anti-inflammatory characteristics, the aim was to develop electrospun fibers from PBAT (poly (butylene-adipate-co-terephthalate)/PCL (poly(ε-caprolactone) containing propolis in order to promote antimicrobial action and the healing of wounds. By the optical microscopy analysis, the best parameter for obtaining the fibers was chosen: 16.5% (v/v) of propolis extract alcoholic solution, 14.0 cm needle-collector distance, 17.0 kV of voltage and 0.5 mL h-1 flow rate. The scanning electron microscopy demonstrated fiber diameters of 0.51 ± 0.12 μm for the polymer blend and 1.16 ± 0.98 μm for the blend with propolis. The Fourier transform infrared spectroscopy (FTIR) results showed no evidence of chemical interaction with propolis, this being a physical interaction. This interaction was corroborated by the differential scanning calorimetry (DSC) due to the variation in the heats involved, mainly in the aromatic part of the polymer blend, indicating a better interaction in the PBAT group. Finally, it was found that fibers presents propolis antimicrobial activity against the bacteria Pseudomonas Aeruginosa. The results indicate that this blend has a great potential to be used as a cutaneous dressing. |
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ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSINGelectrospunantimicrobialwound dressingThe electrospinning has been widely used in tissue engineering for the preparation of wound dressing with the most varied polymers and drugs. Considering that propolis has antimicrobial and anti-inflammatory characteristics, the aim was to develop electrospun fibers from PBAT (poly (butylene-adipate-co-terephthalate)/PCL (poly(ε-caprolactone) containing propolis in order to promote antimicrobial action and the healing of wounds. By the optical microscopy analysis, the best parameter for obtaining the fibers was chosen: 16.5% (v/v) of propolis extract alcoholic solution, 14.0 cm needle-collector distance, 17.0 kV of voltage and 0.5 mL h-1 flow rate. The scanning electron microscopy demonstrated fiber diameters of 0.51 ± 0.12 μm for the polymer blend and 1.16 ± 0.98 μm for the blend with propolis. The Fourier transform infrared spectroscopy (FTIR) results showed no evidence of chemical interaction with propolis, this being a physical interaction. This interaction was corroborated by the differential scanning calorimetry (DSC) due to the variation in the heats involved, mainly in the aromatic part of the polymer blend, indicating a better interaction in the PBAT group. Finally, it was found that fibers presents propolis antimicrobial activity against the bacteria Pseudomonas Aeruginosa. The results indicate that this blend has a great potential to be used as a cutaneous dressing.Sociedade Brasileira de Química2021-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021001001245Química Nova v.44 n.10 2021reponame:Química Nova (Online)instname:Sociedade Brasileira de Química (SBQ)instacron:SBQ10.21577/0100-4042.20170787info:eu-repo/semantics/openAccessZanella,Heloisa G.Rossin,Ariane R. SouzaHardt,Janice CarolineRosenberger,Andressa G.Wiggers,Juliana C.Caetano,JosianeDragunski,Douglas C.eng2021-12-16T00:00:00Zoai:scielo:S0100-40422021001001245Revistahttps://www.scielo.br/j/qn/ONGhttps://old.scielo.br/oai/scielo-oai.phpquimicanova@sbq.org.br1678-70640100-4042opendoar:2021-12-16T00:00Química Nova (Online) - Sociedade Brasileira de Química (SBQ)false |
dc.title.none.fl_str_mv |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
title |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
spellingShingle |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING Zanella,Heloisa G. electrospun antimicrobial wound dressing |
title_short |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
title_full |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
title_fullStr |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
title_full_unstemmed |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
title_sort |
ELECTROSPINNING PBAT (POLY (BUTYLENE-ADIPATE-CO-TEREPHTHALATE))/PCL (POLY(ɛ-CAPROLACTONE) BLEND CONTAINING PROPOLIS FOR THE PREPARATION OF A SMART WOUND DRESSING |
author |
Zanella,Heloisa G. |
author_facet |
Zanella,Heloisa G. Rossin,Ariane R. Souza Hardt,Janice Caroline Rosenberger,Andressa G. Wiggers,Juliana C. Caetano,Josiane Dragunski,Douglas C. |
author_role |
author |
author2 |
Rossin,Ariane R. Souza Hardt,Janice Caroline Rosenberger,Andressa G. Wiggers,Juliana C. Caetano,Josiane Dragunski,Douglas C. |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Zanella,Heloisa G. Rossin,Ariane R. Souza Hardt,Janice Caroline Rosenberger,Andressa G. Wiggers,Juliana C. Caetano,Josiane Dragunski,Douglas C. |
dc.subject.por.fl_str_mv |
electrospun antimicrobial wound dressing |
topic |
electrospun antimicrobial wound dressing |
description |
The electrospinning has been widely used in tissue engineering for the preparation of wound dressing with the most varied polymers and drugs. Considering that propolis has antimicrobial and anti-inflammatory characteristics, the aim was to develop electrospun fibers from PBAT (poly (butylene-adipate-co-terephthalate)/PCL (poly(ε-caprolactone) containing propolis in order to promote antimicrobial action and the healing of wounds. By the optical microscopy analysis, the best parameter for obtaining the fibers was chosen: 16.5% (v/v) of propolis extract alcoholic solution, 14.0 cm needle-collector distance, 17.0 kV of voltage and 0.5 mL h-1 flow rate. The scanning electron microscopy demonstrated fiber diameters of 0.51 ± 0.12 μm for the polymer blend and 1.16 ± 0.98 μm for the blend with propolis. The Fourier transform infrared spectroscopy (FTIR) results showed no evidence of chemical interaction with propolis, this being a physical interaction. This interaction was corroborated by the differential scanning calorimetry (DSC) due to the variation in the heats involved, mainly in the aromatic part of the polymer blend, indicating a better interaction in the PBAT group. Finally, it was found that fibers presents propolis antimicrobial activity against the bacteria Pseudomonas Aeruginosa. The results indicate that this blend has a great potential to be used as a cutaneous dressing. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021001001245 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422021001001245 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.21577/0100-4042.20170787 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
publisher.none.fl_str_mv |
Sociedade Brasileira de Química |
dc.source.none.fl_str_mv |
Química Nova v.44 n.10 2021 reponame:Química Nova (Online) instname:Sociedade Brasileira de Química (SBQ) instacron:SBQ |
instname_str |
Sociedade Brasileira de Química (SBQ) |
instacron_str |
SBQ |
institution |
SBQ |
reponame_str |
Química Nova (Online) |
collection |
Química Nova (Online) |
repository.name.fl_str_mv |
Química Nova (Online) - Sociedade Brasileira de Química (SBQ) |
repository.mail.fl_str_mv |
quimicanova@sbq.org.br |
_version_ |
1750318121511550976 |