Primary telencephalic lymphoma in a horse

Detalhes bibliográficos
Autor(a) principal: Marcolongo-Pereira, Clairton
Data de Publicação: 2015
Outros Autores: Curcio, Bruna da Rosa, Oliveira, Douglas Pacheco, Coelho, Ana Carolina Barreto, Santos, Bianca Lemos, Schild, Ana Lucia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Semina. Ciências Agrárias (Online)
Texto Completo: https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179
Resumo: A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs.
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spelling Primary telencephalic lymphoma in a horseLinfoma telencefálico primário em um equinoLymphomaCD3Central nervous systemHorse.LinfomaCD3Sistema nervoso centralEqüino.A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs. Descreve-se um caso de linfoma T do tipo células pequenas no encéfalo de um equino de 20 anos da raça Crioula, que apresentou sinais neurológicos caracterizados por incoordenação motora, andar em círculos e perda parcial do olfato e da visão. Na necropsia havia, desde o bulbo olfatório se estendendo até a cápsula interna do telencéfalo direito, uma massa esbranquiçada e firme, não encapsulada, que comprimia as estruturas do tecido nervoso. Histologicamente havia proliferação de células redondas, com citoplasma escasso a moderado e eosinofílico. Os núcleos eram redondos, localizados centralmente e ocasionalmente endentados e hipercromáticos. Na imuno-histoquímica houve imunomarcação citoplasmática moderada para CD3. Este é um linfoma primário raro do sistema nervoso central de equinos com escassos relatos na literatura veterinária, no entanto, deve ser levado em consideração como diagnóstico diferencial em equinos com sinais neurológicos. UEL2015-12-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de casoapplication/pdfimage/jpegimage/jpegapplication/pdfapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2017910.5433/1679-0359.2015v36n6p3801Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3801-3806Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3801-38061679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/17476https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35088https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35089https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35090https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/36774Marcolongo-Pereira, ClairtonCurcio, Bruna da RosaOliveira, Douglas PachecoCoelho, Ana Carolina BarretoSantos, Bianca LemosSchild, Ana Luciainfo:eu-repo/semantics/openAccess2015-12-09T15:01:19Zoai:ojs.pkp.sfu.ca:article/20179Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2015-12-09T15:01:19Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false
dc.title.none.fl_str_mv Primary telencephalic lymphoma in a horse
Linfoma telencefálico primário em um equino
title Primary telencephalic lymphoma in a horse
spellingShingle Primary telencephalic lymphoma in a horse
Marcolongo-Pereira, Clairton
Lymphoma
CD3
Central nervous system
Horse.
Linfoma
CD3
Sistema nervoso central
Eqüino.
title_short Primary telencephalic lymphoma in a horse
title_full Primary telencephalic lymphoma in a horse
title_fullStr Primary telencephalic lymphoma in a horse
title_full_unstemmed Primary telencephalic lymphoma in a horse
title_sort Primary telencephalic lymphoma in a horse
author Marcolongo-Pereira, Clairton
author_facet Marcolongo-Pereira, Clairton
Curcio, Bruna da Rosa
Oliveira, Douglas Pacheco
Coelho, Ana Carolina Barreto
Santos, Bianca Lemos
Schild, Ana Lucia
author_role author
author2 Curcio, Bruna da Rosa
Oliveira, Douglas Pacheco
Coelho, Ana Carolina Barreto
Santos, Bianca Lemos
Schild, Ana Lucia
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Marcolongo-Pereira, Clairton
Curcio, Bruna da Rosa
Oliveira, Douglas Pacheco
Coelho, Ana Carolina Barreto
Santos, Bianca Lemos
Schild, Ana Lucia
dc.subject.por.fl_str_mv Lymphoma
CD3
Central nervous system
Horse.
Linfoma
CD3
Sistema nervoso central
Eqüino.
topic Lymphoma
CD3
Central nervous system
Horse.
Linfoma
CD3
Sistema nervoso central
Eqüino.
description A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs.
publishDate 2015
dc.date.none.fl_str_mv 2015-12-09
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Relato de caso
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179
10.5433/1679-0359.2015v36n6p3801
url https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179
identifier_str_mv 10.5433/1679-0359.2015v36n6p3801
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/17476
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35088
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35089
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/35090
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/36774
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
image/jpeg
image/jpeg
application/pdf
application/pdf
dc.publisher.none.fl_str_mv UEL
publisher.none.fl_str_mv UEL
dc.source.none.fl_str_mv Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3801-3806
Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3801-3806
1679-0359
1676-546X
reponame:Semina. Ciências Agrárias (Online)
instname:Universidade Estadual de Londrina (UEL)
instacron:UEL
instname_str Universidade Estadual de Londrina (UEL)
instacron_str UEL
institution UEL
reponame_str Semina. Ciências Agrárias (Online)
collection Semina. Ciências Agrárias (Online)
repository.name.fl_str_mv Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)
repository.mail.fl_str_mv semina.agrarias@uel.br
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