Primary telencephalic lymphoma in a horse
Autor(a) principal: | |
---|---|
Data de Publicação: | 2015 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Semina. Ciências Agrárias (Online) |
Texto Completo: | https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179 |
Resumo: | A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs. |
id |
UEL-11_2e21b5c166bea2eb31148ee72b77fd50 |
---|---|
oai_identifier_str |
oai:ojs.pkp.sfu.ca:article/20179 |
network_acronym_str |
UEL-11 |
network_name_str |
Semina. Ciências Agrárias (Online) |
repository_id_str |
|
spelling |
Primary telencephalic lymphoma in a horseLinfoma telencefálico primário em um equinoLymphomaCD3Central nervous systemHorse.LinfomaCD3Sistema nervoso centralEqüino.A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs. Descreve-se um caso de linfoma T do tipo células pequenas no encéfalo de um equino de 20 anos da raça Crioula, que apresentou sinais neurológicos caracterizados por incoordenação motora, andar em círculos e perda parcial do olfato e da visão. Na necropsia havia, desde o bulbo olfatório se estendendo até a cápsula interna do telencéfalo direito, uma massa esbranquiçada e firme, não encapsulada, que comprimia as estruturas do tecido nervoso. Histologicamente havia proliferação de células redondas, com citoplasma escasso a moderado e eosinofílico. Os núcleos eram redondos, localizados centralmente e ocasionalmente endentados e hipercromáticos. Na imuno-histoquímica houve imunomarcação citoplasmática moderada para CD3. Este é um linfoma primário raro do sistema nervoso central de equinos com escassos relatos na literatura veterinária, no entanto, deve ser levado em consideração como diagnóstico diferencial em equinos com sinais neurológicos. UEL2015-12-09info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionRelato de casoapplication/pdfhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/2017910.5433/1679-0359.2015v36n6p3801Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3801-3806Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3801-38061679-03591676-546Xreponame:Semina. Ciências Agrárias (Online)instname:Universidade Estadual de Londrina (UEL)instacron:UELenghttps://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/17476http://creativecommons.org/licenses/by-nc/4.0info:eu-repo/semantics/openAccessMarcolongo-Pereira, ClairtonCurcio, Bruna da RosaOliveira, Douglas PachecoCoelho, Ana Carolina BarretoSantos, Bianca LemosSchild, Ana Lucia2022-12-05T12:13:11Zoai:ojs.pkp.sfu.ca:article/20179Revistahttp://www.uel.br/revistas/uel/index.php/semagrariasPUBhttps://ojs.uel.br/revistas/uel/index.php/semagrarias/oaisemina.agrarias@uel.br1679-03591676-546Xopendoar:2022-12-05T12:13:11Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL)false |
dc.title.none.fl_str_mv |
Primary telencephalic lymphoma in a horse Linfoma telencefálico primário em um equino |
title |
Primary telencephalic lymphoma in a horse |
spellingShingle |
Primary telencephalic lymphoma in a horse Marcolongo-Pereira, Clairton Lymphoma CD3 Central nervous system Horse. Linfoma CD3 Sistema nervoso central Eqüino. |
title_short |
Primary telencephalic lymphoma in a horse |
title_full |
Primary telencephalic lymphoma in a horse |
title_fullStr |
Primary telencephalic lymphoma in a horse |
title_full_unstemmed |
Primary telencephalic lymphoma in a horse |
title_sort |
Primary telencephalic lymphoma in a horse |
author |
Marcolongo-Pereira, Clairton |
author_facet |
Marcolongo-Pereira, Clairton Curcio, Bruna da Rosa Oliveira, Douglas Pacheco Coelho, Ana Carolina Barreto Santos, Bianca Lemos Schild, Ana Lucia |
author_role |
author |
author2 |
Curcio, Bruna da Rosa Oliveira, Douglas Pacheco Coelho, Ana Carolina Barreto Santos, Bianca Lemos Schild, Ana Lucia |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Marcolongo-Pereira, Clairton Curcio, Bruna da Rosa Oliveira, Douglas Pacheco Coelho, Ana Carolina Barreto Santos, Bianca Lemos Schild, Ana Lucia |
dc.subject.por.fl_str_mv |
Lymphoma CD3 Central nervous system Horse. Linfoma CD3 Sistema nervoso central Eqüino. |
topic |
Lymphoma CD3 Central nervous system Horse. Linfoma CD3 Sistema nervoso central Eqüino. |
description |
A case of T small cell type lymphoma in the brain of a horse is described. A 20-year-old female Crioulo equine showed neurological signs characterized by ataxia, circling and partial loss of smell and sight. During necropsy, a whitish, firm, unencapsulated mass compressing the structures of the nervous tissue was observed, extending from the olfactory bulb to the internal capsule of the right telencephalon. Microscopic examination showed the proliferation of round cells with a small to moderate amount of eosinophilic cytoplasm. Nuclei were centrally located, irregularly round and occasionally cleaved and hyperchromatic. Immunohistochemistry for CD3 showed a moderate diffuse cytoplasmic staining. This is a rare primary central nervous system lymphoma in horses, with few reports in the veterinary literature. Nevertheless, it should be considered as a differential diagnosis in equines with neurological signs. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-09 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Relato de caso |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179 10.5433/1679-0359.2015v36n6p3801 |
url |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179 |
identifier_str_mv |
10.5433/1679-0359.2015v36n6p3801 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://ojs.uel.br/revistas/uel/index.php/semagrarias/article/view/20179/17476 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by-nc/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by-nc/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
UEL |
publisher.none.fl_str_mv |
UEL |
dc.source.none.fl_str_mv |
Semina: Ciências Agrárias; Vol. 36 No. 6 (2015); 3801-3806 Semina: Ciências Agrárias; v. 36 n. 6 (2015); 3801-3806 1679-0359 1676-546X reponame:Semina. Ciências Agrárias (Online) instname:Universidade Estadual de Londrina (UEL) instacron:UEL |
instname_str |
Universidade Estadual de Londrina (UEL) |
instacron_str |
UEL |
institution |
UEL |
reponame_str |
Semina. Ciências Agrárias (Online) |
collection |
Semina. Ciências Agrárias (Online) |
repository.name.fl_str_mv |
Semina. Ciências Agrárias (Online) - Universidade Estadual de Londrina (UEL) |
repository.mail.fl_str_mv |
semina.agrarias@uel.br |
_version_ |
1799306073265405952 |