Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population

Detalhes bibliográficos
Autor(a) principal: Blanton, Ronald Edward
Data de Publicação: 2008
Outros Autores: Silva, Luciano K., Morato, Vanessa G., Parrado, Antonio R., Dias, Juarez Pereira, Melo, Paulo Roberto Santana de, Reis, Eliana A. G., Goddard, Katrina A. B., Nunes, Márcio Roberto Teixeira, Rodrigues, Sueli G., Vasconcelos, Pedro F. C., Castro, Jesuina M., Reis, Mitermayer Galvão dos, Barreto, Mauricio Lima, Teixeira, Maria da Glória Lima Cruz
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/2060
Resumo: p.762-765
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spelling Blanton, Ronald EdwardSilva, Luciano K.Morato, Vanessa G.Parrado, Antonio R.Dias, Juarez PereiraMelo, Paulo Roberto Santana deReis, Eliana A. G.Goddard, Katrina A. B.Nunes, Márcio Roberto TeixeiraRodrigues, Sueli G.Vasconcelos, Pedro F. C.Castro, Jesuina M.Reis, Mitermayer Galvão dosBarreto, Mauricio LimaTeixeira, Maria da Glória Lima CruzBlanton, Ronald EdwardSilva, Luciano K.Morato, Vanessa G.Parrado, Antonio R.Dias, Juarez PereiraMelo, Paulo Roberto Santana deReis, Eliana A. G.Goddard, Katrina A. B.Nunes, Márcio Roberto TeixeiraRodrigues, Sueli G.Vasconcelos, Pedro F. C.Castro, Jesuina M.Reis, Mitermayer Galvão dosBarreto, Mauricio LimaTeixeira, Maria da Glória Lima Cruz2011-08-05T01:08:01Z2011-08-05T01:08:01Z2008-02-131018-4813/08http://www.repositorio.ufba.br/ri/handle/ri/2060v. 16p.762-765To test whether African ancestry is protective for severe dengue, we genotyped 49 hospitalized cases of dengue hemorrhagic fever(DHF)as well as 293 neighborhood cases of dengue fevre and 294 asymptomatic controls in Salvador, Bahia, Brazil.Ancestry-informative markers and 282 unlinked SNPs not associated with the clinical presentation of dengue were used to estimate ancestry. After controlling for income,both self-defined Afro-Brazilian ethnicity and African ancestry were protective for DHF (P=0.02, OR=0.28 and P=0.02,OR=0.13,respectively).Income or an index of income indicators, however,was also independently associated with the diagnosis of DHF.Submitted by Rigaud Andréa (andrearigaud16@yahoo.com.br) on 2011-08-05T01:08:01Z No. of bitstreams: 1 per%20int2008.4[1].pdf: 115239 bytes, checksum: 910b1e8af0e8f506e9776e1c78ae926b (MD5)Made available in DSpace on 2011-08-05T01:08:01Z (GMT). No. of bitstreams: 1 per%20int2008.4[1].pdf: 115239 bytes, checksum: 910b1e8af0e8f506e9776e1c78ae926b (MD5) Previous issue date: 2008-02-13ethnicityracepopulation structuresocioeconomic statusDENV3Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed populationEuropean Journal of Human Geneticsinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessORIGINALper%20int2008.4[1].pdfper%20int2008.4[1].pdfapplication/pdf115239https://repositorio.ufba.br/bitstream/ri/2060/1/per%2520int2008.4%5b1%5d.pdf910b1e8af0e8f506e9776e1c78ae926bMD51LICENSElicense.txtlicense.txttext/plain1906https://repositorio.ufba.br/bitstream/ri/2060/2/license.txt4be0ee38b9d32b8a2f24a1b9348d947dMD52TEXTper%20int2008.4[1].pdf.txtper%20int2008.4[1].pdf.txtExtracted texttext/plain15543https://repositorio.ufba.br/bitstream/ri/2060/3/per%2520int2008.4%5b1%5d.pdf.txt191f05d987b3de7d6b9c818e8203e8c8MD53ri/20602022-07-05 14:03:43.313oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:43Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
dc.title.alternative.pt_BR.fl_str_mv European Journal of Human Genetics
title Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
spellingShingle Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
Blanton, Ronald Edward
ethnicity
race
population structure
socioeconomic status
DENV3
title_short Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
title_full Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
title_fullStr Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
title_full_unstemmed Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
title_sort Genetic ancestry and income are associated with dengue Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population
author Blanton, Ronald Edward
author_facet Blanton, Ronald Edward
Silva, Luciano K.
Morato, Vanessa G.
Parrado, Antonio R.
Dias, Juarez Pereira
Melo, Paulo Roberto Santana de
Reis, Eliana A. G.
Goddard, Katrina A. B.
Nunes, Márcio Roberto Teixeira
Rodrigues, Sueli G.
Vasconcelos, Pedro F. C.
Castro, Jesuina M.
Reis, Mitermayer Galvão dos
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
author_role author
author2 Silva, Luciano K.
Morato, Vanessa G.
Parrado, Antonio R.
Dias, Juarez Pereira
Melo, Paulo Roberto Santana de
Reis, Eliana A. G.
Goddard, Katrina A. B.
Nunes, Márcio Roberto Teixeira
Rodrigues, Sueli G.
Vasconcelos, Pedro F. C.
Castro, Jesuina M.
Reis, Mitermayer Galvão dos
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Blanton, Ronald Edward
Silva, Luciano K.
Morato, Vanessa G.
Parrado, Antonio R.
Dias, Juarez Pereira
Melo, Paulo Roberto Santana de
Reis, Eliana A. G.
Goddard, Katrina A. B.
Nunes, Márcio Roberto Teixeira
Rodrigues, Sueli G.
Vasconcelos, Pedro F. C.
Castro, Jesuina M.
Reis, Mitermayer Galvão dos
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
Blanton, Ronald Edward
Silva, Luciano K.
Morato, Vanessa G.
Parrado, Antonio R.
Dias, Juarez Pereira
Melo, Paulo Roberto Santana de
Reis, Eliana A. G.
Goddard, Katrina A. B.
Nunes, Márcio Roberto Teixeira
Rodrigues, Sueli G.
Vasconcelos, Pedro F. C.
Castro, Jesuina M.
Reis, Mitermayer Galvão dos
Barreto, Mauricio Lima
Teixeira, Maria da Glória Lima Cruz
dc.subject.por.fl_str_mv ethnicity
race
population structure
socioeconomic status
DENV3
topic ethnicity
race
population structure
socioeconomic status
DENV3
description p.762-765
publishDate 2008
dc.date.issued.fl_str_mv 2008-02-13
dc.date.accessioned.fl_str_mv 2011-08-05T01:08:01Z
dc.date.available.fl_str_mv 2011-08-05T01:08:01Z
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dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.issn.none.fl_str_mv 1018-4813/08
dc.identifier.number.pt_BR.fl_str_mv v. 16
identifier_str_mv 1018-4813/08
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