Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats

Detalhes bibliográficos
Autor(a) principal: José Antunes Rodrigues, José Antunes Rodrigues
Data de Publicação: 2003
Outros Autores: Rodriguez, Tânia Tavares, Reis, Luis Carlos, Araújo, Wladyslawa Ivanovna Cavalcanti de Albuquerque, Ramalho, Maria José Pedreira
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UFBA
Texto Completo: http://www.repositorio.ufba.br/ri/handle/ri/5060
Resumo: p.755–760.
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spelling José Antunes Rodrigues, José Antunes RodriguesRodriguez, Tânia TavaresReis, Luis CarlosAraújo, Wladyslawa Ivanovna Cavalcanti de AlbuquerqueRamalho, Maria José PedreiraJosé Antunes Rodrigues, José Antunes RodriguesRodriguez, Tânia TavaresReis, Luis CarlosAraújo, Wladyslawa Ivanovna Cavalcanti de AlbuquerqueRamalho, Maria José Pedreira2012-01-07T00:37:00Z2012-01-07T00:37:00Z20031469-445Xhttp://www.repositorio.ufba.br/ri/handle/ri/5060v. 88, n. 6.p.755–760.We investigated the effects of sepsis, through the lipopolysaccharide (LPS)-induced inflammatory response, on plasma corticosterone and prolactin (PRL) levels during acute immobilization stress in normal and thyroidectomized rats. Thyroidectomized (TX) or sham-operated (N) rats were subjected to 120 min of immobilization stress. Rats were treated with an intraperitoneal injection of either LPS (250 mg (100 g body wt)_1) or the same volume of vehicle (saline solution), 90 min before the induction of stress. Blood samples for hormone assays were collected before sepsis and stress induction for baseline measures (_90 min), and during sepsis and immobilization stress for the measurement of prolactin and corticosterone levels by radioimmunoassay. Our results show that the thyroid hormones are necessary for a proper response of PRL and corticosterone release during immobilization stress. Although sepsis enhanced PRL secretion, this was not true of corticosterone release in either group of rats. Low levels of thyroid hormones partially block the release of PRL, but do not block corticosterone secretion during sepsis.Submitted by Ana Valéria de Jesus Moura (anavaleria_131@hotmail.com) on 2012-01-07T00:37:00Z No. of bitstreams: 1 755.full.pdf: 144381 bytes, checksum: 2fd55bfd7b2c3edb837f1eb62db0a6ea (MD5)Made available in DSpace on 2012-01-07T00:37:00Z (GMT). No. of bitstreams: 1 755.full.pdf: 144381 bytes, checksum: 2fd55bfd7b2c3edb837f1eb62db0a6ea (MD5) Previous issue date: 2003Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic ratsExperimental Physiologyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleengreponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAinfo:eu-repo/semantics/openAccessLICENSElicense.txtlicense.txttext/plain1762https://repositorio.ufba.br/bitstream/ri/5060/2/license.txt1b89a9a0548218172d7c829f87a0eab9MD52ORIGINAL755.full.pdf755.full.pdfapplication/pdf144381https://repositorio.ufba.br/bitstream/ri/5060/1/755.full.pdf2fd55bfd7b2c3edb837f1eb62db0a6eaMD51TEXT755.full.pdf.txt755.full.pdf.txtExtracted texttext/plain30540https://repositorio.ufba.br/bitstream/ri/5060/3/755.full.pdf.txtcd75a076db9b24630f4565a973793e9eMD53ri/50602022-07-05 14:03:16.125oai:repositorio.ufba.br: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Repositório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-07-05T17:03:16Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false
dc.title.pt_BR.fl_str_mv Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
dc.title.alternative.pt_BR.fl_str_mv Experimental Physiology
title Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
spellingShingle Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
José Antunes Rodrigues, José Antunes Rodrigues
title_short Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
title_full Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
title_fullStr Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
title_full_unstemmed Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
title_sort Hypothyroidism attenuates stress-induced prolactin and corticosterone release in septic rats
author José Antunes Rodrigues, José Antunes Rodrigues
author_facet José Antunes Rodrigues, José Antunes Rodrigues
Rodriguez, Tânia Tavares
Reis, Luis Carlos
Araújo, Wladyslawa Ivanovna Cavalcanti de Albuquerque
Ramalho, Maria José Pedreira
author_role author
author2 Rodriguez, Tânia Tavares
Reis, Luis Carlos
Araújo, Wladyslawa Ivanovna Cavalcanti de Albuquerque
Ramalho, Maria José Pedreira
author2_role author
author
author
author
dc.contributor.author.fl_str_mv José Antunes Rodrigues, José Antunes Rodrigues
Rodriguez, Tânia Tavares
Reis, Luis Carlos
Araújo, Wladyslawa Ivanovna Cavalcanti de Albuquerque
Ramalho, Maria José Pedreira
José Antunes Rodrigues, José Antunes Rodrigues
Rodriguez, Tânia Tavares
Reis, Luis Carlos
Araújo, Wladyslawa Ivanovna Cavalcanti de Albuquerque
Ramalho, Maria José Pedreira
description p.755–760.
publishDate 2003
dc.date.issued.fl_str_mv 2003
dc.date.accessioned.fl_str_mv 2012-01-07T00:37:00Z
dc.date.available.fl_str_mv 2012-01-07T00:37:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://www.repositorio.ufba.br/ri/handle/ri/5060
dc.identifier.issn.none.fl_str_mv 1469-445X
dc.identifier.number.pt_BR.fl_str_mv v. 88, n. 6.
identifier_str_mv 1469-445X
v. 88, n. 6.
url http://www.repositorio.ufba.br/ri/handle/ri/5060
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.source.none.fl_str_mv reponame:Repositório Institucional da UFBA
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reponame_str Repositório Institucional da UFBA
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