Structural studies of 4-aminoantipyrine derivatives
Autor(a) principal: | |
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Data de Publicação: | 2005 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFBA |
Texto Completo: | http://repositorio.ufba.br/ri/handle/ri/13542 |
Resumo: | Texto completo: acesso restrito. p.32–39 |
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Cunha, Silvio do DesterroOliveira, Shana M.Rodrigues Jr, Manoel T.Bastos, Rodrigo M.Ferrari, JailtonOliveira, Cecília M.A. deKato, LucíliaNapolitano, Hamilton B.Vencato, IvoLariucci, CarlitoCunha, Silvio do DesterroOliveira, Shana M.Rodrigues Jr, Manoel T.Bastos, Rodrigo M.Ferrari, JailtonOliveira, Cecília M.A. deKato, LucíliaNapolitano, Hamilton B.Vencato, IvoLariucci, Carlito2013-11-04T11:43:29Z20050022-2860http://repositorio.ufba.br/ri/handle/ri/13542v.752 n. 1-3Texto completo: acesso restrito. p.32–39Reaction of 4-aminoantipyrine with acetylacetone, ethyl acetoacetate, benzoyl isothiocyanate, phenyl isothiocyanate, maleic anhydride and methoxymethylene Meldrum's acid afforded a series of new antipyrine derivatives. The antibacterial activity of the synthesized compounds against Micrococcus luteus ATCC 9341, Staphilococcus aureus ATCC 29737, and Escherichia coli ATCC 8739 was evaluated and the minimal inhibitory concentration determined. Modest activity was found only to the maleamic acid obtained from the reaction of 4-aminoantipyrine and maleic anhydride. 1H NMR investigation of this maleamic acid showed that it is slowly converted to the corresponding toxic maleimide. The structures of three derivatives were determined by X-ray diffraction analysis.Submitted by Edileide Reis (leyde-landy@hotmail.com) on 2013-11-04T11:43:29Z No. of bitstreams: 1 Silvio Cunha.pdf: 266922 bytes, checksum: 4445b82708b0cf11f9e50dce2fab1938 (MD5)Made available in DSpace on 2013-11-04T11:43:29Z (GMT). No. of bitstreams: 1 Silvio Cunha.pdf: 266922 bytes, checksum: 4445b82708b0cf11f9e50dce2fab1938 (MD5) Previous issue date: 2005http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.molstruc.2005.05.016reponame:Repositório Institucional da UFBAinstname:Universidade Federal da Bahia (UFBA)instacron:UFBAEnaminonesThioureasMeleimideStructural studies of 4-aminoantipyrine derivativesJournal of Molecular Structureinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10000-01-01info:eu-repo/semantics/openAccessengORIGINALSilvio Cunha.pdfSilvio Cunha.pdfapplication/pdf266922https://repositorio.ufba.br/bitstream/ri/13542/1/Silvio%20Cunha.pdf4445b82708b0cf11f9e50dce2fab1938MD51LICENSElicense.txtlicense.txttext/plain1383https://repositorio.ufba.br/bitstream/ri/13542/2/license.txt05eca2f01d0b3307819d0369dab18a34MD52TEXTSilvio Cunha.pdf.txtSilvio Cunha.pdf.txtExtracted texttext/plain24917https://repositorio.ufba.br/bitstream/ri/13542/3/Silvio%20Cunha.pdf.txtf4ff994ff1156c87e69fe62433f9c408MD53ri/135422022-08-08 13:17:50.0oai:repositorio.ufba.br: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ório InstitucionalPUBhttp://192.188.11.11:8080/oai/requestopendoar:19322022-08-08T16:17:50Repositório Institucional da UFBA - Universidade Federal da Bahia (UFBA)false |
dc.title.pt_BR.fl_str_mv |
Structural studies of 4-aminoantipyrine derivatives |
dc.title.alternative.pt_BR.fl_str_mv |
Journal of Molecular Structure |
title |
Structural studies of 4-aminoantipyrine derivatives |
spellingShingle |
Structural studies of 4-aminoantipyrine derivatives Cunha, Silvio do Desterro Enaminones Thioureas Meleimide |
title_short |
Structural studies of 4-aminoantipyrine derivatives |
title_full |
Structural studies of 4-aminoantipyrine derivatives |
title_fullStr |
Structural studies of 4-aminoantipyrine derivatives |
title_full_unstemmed |
Structural studies of 4-aminoantipyrine derivatives |
title_sort |
Structural studies of 4-aminoantipyrine derivatives |
author |
Cunha, Silvio do Desterro |
author_facet |
Cunha, Silvio do Desterro Oliveira, Shana M. Rodrigues Jr, Manoel T. Bastos, Rodrigo M. Ferrari, Jailton Oliveira, Cecília M.A. de Kato, Lucília Napolitano, Hamilton B. Vencato, Ivo Lariucci, Carlito |
author_role |
author |
author2 |
Oliveira, Shana M. Rodrigues Jr, Manoel T. Bastos, Rodrigo M. Ferrari, Jailton Oliveira, Cecília M.A. de Kato, Lucília Napolitano, Hamilton B. Vencato, Ivo Lariucci, Carlito |
author2_role |
author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Cunha, Silvio do Desterro Oliveira, Shana M. Rodrigues Jr, Manoel T. Bastos, Rodrigo M. Ferrari, Jailton Oliveira, Cecília M.A. de Kato, Lucília Napolitano, Hamilton B. Vencato, Ivo Lariucci, Carlito Cunha, Silvio do Desterro Oliveira, Shana M. Rodrigues Jr, Manoel T. Bastos, Rodrigo M. Ferrari, Jailton Oliveira, Cecília M.A. de Kato, Lucília Napolitano, Hamilton B. Vencato, Ivo Lariucci, Carlito |
dc.subject.por.fl_str_mv |
Enaminones Thioureas Meleimide |
topic |
Enaminones Thioureas Meleimide |
description |
Texto completo: acesso restrito. p.32–39 |
publishDate |
2005 |
dc.date.issued.fl_str_mv |
2005 |
dc.date.accessioned.fl_str_mv |
2013-11-04T11:43:29Z |
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info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://repositorio.ufba.br/ri/handle/ri/13542 |
dc.identifier.issn.none.fl_str_mv |
0022-2860 |
dc.identifier.number.pt_BR.fl_str_mv |
v.752 n. 1-3 |
identifier_str_mv |
0022-2860 v.752 n. 1-3 |
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http://repositorio.ufba.br/ri/handle/ri/13542 |
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eng |
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eng |
dc.rights.driver.fl_str_mv |
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openAccess |
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http://dx.doi.org.ez10.periodicos.capes.gov.br/10.1016/j.molstruc.2005.05.016 |
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reponame:Repositório Institucional da UFBA instname:Universidade Federal da Bahia (UFBA) instacron:UFBA |
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