GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD

Detalhes bibliográficos
Autor(a) principal: Ferreira, Reginaldo Nassar
Data de Publicação: 2007
Outros Autores: Almeida, Liliane Araújo Mendes de, Ferreira, Rejane Costa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Pesquisa Agropecuária Tropical (Online)
Texto Completo: https://revistas.ufg.br/pat/article/view/2736
Resumo: Twenty thirty day-old male mice weighing 25 g were divided in two groups: Group 1: oral saline solution (control), and Group 2: oral gossipol acetic-acid at 20 mg/kg. Forty days after treatments and leukocytes were counted through Newbawer counting chamber. Leukometry showed 9,241 leukocytes/mm3 for the control and 6,125 leukocytes/mm3 for the gossipol treated group (significant difference for P=0.05). Erythrometry showed 6,596,000 erythrocytes/mm3 and 6,399,000 erythrocytes/mm3 for control and gossipol treated mice, respectively. It was concluded that gossipol may induce a deleterious effect on the organism defense cells. KEY-WORDS: Gossipol; mice; blood.
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spelling GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOODESTUDO DO EFEITO DO GOSSIPOL NO SANGUE DE CAMUNDONGOS (Mus domesticus domesticus)GossipolmicebloodGossipolsangueMus Twenty thirty day-old male mice weighing 25 g were divided in two groups: Group 1: oral saline solution (control), and Group 2: oral gossipol acetic-acid at 20 mg/kg. Forty days after treatments and leukocytes were counted through Newbawer counting chamber. Leukometry showed 9,241 leukocytes/mm3 for the control and 6,125 leukocytes/mm3 for the gossipol treated group (significant difference for P=0.05). Erythrometry showed 6,596,000 erythrocytes/mm3 and 6,399,000 erythrocytes/mm3 for control and gossipol treated mice, respectively. It was concluded that gossipol may induce a deleterious effect on the organism defense cells. KEY-WORDS: Gossipol; mice; blood. O trabalho foi realizado utilizando 20 camundongos (Mus domesticus domesticus) machos, com 30 dias de idade e peso de 25 gramas. Os animais foram divididos em dois grupos: Grupo 1 - Controle - solução salina oral e Grupo 2 - gossipol ácido acético via oral na dose de 20 mg/kg de peso vivo. O experimento teve a duração de 40 dias. Ao final do período, foi feita a determinação de eritrometria e leucometria pela técnica de câmara de contagem de Neubawer. Os resultados observados foram: leucometria (controle = 9.241 leucócitos por mm3 e gossipol = 6.125 leucócitos por mm3 - significativo P= 0,05) e eritometria (controle = 6.596.000 eritrócitos mm3 e gossipol = 6.399.000 eritrócitos mm3). Conclui-se do presente trabalho que o gossipol pode provocar efeitos deletérios nas células de defesa do organismo. PALAVRA-CHAVE: Gossipol; sangue; Mus.Escola de Agronomia - Universidade Federal de Goiás2007-12-12info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionAvaliado por paresapplication/pdfhttps://revistas.ufg.br/pat/article/view/2736Pesquisa Agropecuária Tropical [Agricultural Research in the Tropics]; v. 25, n. 1, Jan./Jun. 1995; 63-68Pesquisa Agropecuária Tropical (Agricultural Research in the Tropics); v. 25, n. 1, jan./jun. 1995; 63-68Pesquisa Agropecuária Tropical; v. 25, n. 1, jan./jun. 1995; 63-681983-4063reponame:Pesquisa Agropecuária Tropical (Online)instname:Universidade Federal de Goiás (UFG)instacron:UFGporhttps://revistas.ufg.br/pat/article/view/2736/2748Ferreira, Reginaldo NassarAlmeida, Liliane Araújo Mendes deFerreira, Rejane Costainfo:eu-repo/semantics/openAccess2009-06-18T18:34:04Zoai:ojs.revistas.ufg.br:article/2736Revistahttps://revistas.ufg.br/patPUBhttps://revistas.ufg.br/pat/oaiaseleguini.pat@gmail.com||mgoes@agro.ufg.br1983-40631517-6398opendoar:2024-05-21T19:55:19.998097Pesquisa Agropecuária Tropical (Online) - Universidade Federal de Goiás (UFG)true
dc.title.none.fl_str_mv GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
ESTUDO DO EFEITO DO GOSSIPOL NO SANGUE DE CAMUNDONGOS (Mus domesticus domesticus)
title GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
spellingShingle GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
Ferreira, Reginaldo Nassar
Gossipol
mice
blood
Gossipol
sangue
Mus
title_short GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
title_full GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
title_fullStr GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
title_full_unstemmed GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
title_sort GOSSIPOL EFFECT ON MICE (Mus domesticus domesticus) BLOOD
author Ferreira, Reginaldo Nassar
author_facet Ferreira, Reginaldo Nassar
Almeida, Liliane Araújo Mendes de
Ferreira, Rejane Costa
author_role author
author2 Almeida, Liliane Araújo Mendes de
Ferreira, Rejane Costa
author2_role author
author
dc.contributor.author.fl_str_mv Ferreira, Reginaldo Nassar
Almeida, Liliane Araújo Mendes de
Ferreira, Rejane Costa
dc.subject.por.fl_str_mv Gossipol
mice
blood
Gossipol
sangue
Mus
topic Gossipol
mice
blood
Gossipol
sangue
Mus
description Twenty thirty day-old male mice weighing 25 g were divided in two groups: Group 1: oral saline solution (control), and Group 2: oral gossipol acetic-acid at 20 mg/kg. Forty days after treatments and leukocytes were counted through Newbawer counting chamber. Leukometry showed 9,241 leukocytes/mm3 for the control and 6,125 leukocytes/mm3 for the gossipol treated group (significant difference for P=0.05). Erythrometry showed 6,596,000 erythrocytes/mm3 and 6,399,000 erythrocytes/mm3 for control and gossipol treated mice, respectively. It was concluded that gossipol may induce a deleterious effect on the organism defense cells. KEY-WORDS: Gossipol; mice; blood.
publishDate 2007
dc.date.none.fl_str_mv 2007-12-12
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Avaliado por pares
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://revistas.ufg.br/pat/article/view/2736
url https://revistas.ufg.br/pat/article/view/2736
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://revistas.ufg.br/pat/article/view/2736/2748
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola de Agronomia - Universidade Federal de Goiás
publisher.none.fl_str_mv Escola de Agronomia - Universidade Federal de Goiás
dc.source.none.fl_str_mv Pesquisa Agropecuária Tropical [Agricultural Research in the Tropics]; v. 25, n. 1, Jan./Jun. 1995; 63-68
Pesquisa Agropecuária Tropical (Agricultural Research in the Tropics); v. 25, n. 1, jan./jun. 1995; 63-68
Pesquisa Agropecuária Tropical; v. 25, n. 1, jan./jun. 1995; 63-68
1983-4063
reponame:Pesquisa Agropecuária Tropical (Online)
instname:Universidade Federal de Goiás (UFG)
instacron:UFG
instname_str Universidade Federal de Goiás (UFG)
instacron_str UFG
institution UFG
reponame_str Pesquisa Agropecuária Tropical (Online)
collection Pesquisa Agropecuária Tropical (Online)
repository.name.fl_str_mv Pesquisa Agropecuária Tropical (Online) - Universidade Federal de Goiás (UFG)
repository.mail.fl_str_mv aseleguini.pat@gmail.com||mgoes@agro.ufg.br
_version_ 1799874815414239232

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