Influence of periodontal treatment on rheumatoid arthritis: a systematic review and meta-analysis

• Autor(a) principal: Débora Cerqueiracalderaro
• Data de Publicação: 2017
• Outros Autores: Jôice Dias Corrêa, Gilda Aparecida Ferreira, Izabela Guimarães Barbosa, Carolina Castro Martins, Tarcília Aparecida da Silva, Antônio Lúcio Teixeira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFMG
• Texto Completo: https://doi.org/10.1016/j.rbre.2016.11.011; http://hdl.handle.net/1843/56477
• topic: Periodontal-systemic disease interactions; Rheumatoid arthritis; Periodontitis; Meta-analysis; Periodontite; Artrite reumatoide; Metanálise

Objective: To evaluate the influence of periodontal treatment on rheumatoid arthritis activity.Methods: MEDLINE/PUBMED, The Cochrane Library, Clinical Trials, SciELO and LILACS were searched for studies published until December 2014. Included articles were: prospective studies; including patients older than 18 years, diagnosed with periodontitis and rheumatoid arthritis submitted to non-surgical periodontal treatment; with a control group receiving no periodontal treatment; with outcomes including at least one marker of rheumatoid arthritis activity. Methodological quality of the studies was assessed using PEDro scale. Quantitative data were pooled in statistical meta-analysis using Review Manager 5. Results: Four articles were included. Non-surgical periodontal treatment was associated with a significant reduction of DAS28 (OR: −1.18; 95% CI: −1.43, −0.93; p < 0.00001). Erythro cyte sedimentation rate, C-reactive protein, patient’s assessment of rheumatoid activity using visual analogical scale, tender and swollen joint counts showed a trend toward reduction (not statistically significant).