Different source of commercial vegetable oils may regulate metabolic, inflammatory and redox status in healthy rats.

• Autor(a) principal: Gomes, Sttefany Viana
• Data de Publicação: 2020
• Outros Autores: Dias, Bruna Vidal, Pereira, Renata Rebeca, Lúcio, Karine de Pádua, Souza, Débora Maria Soares de, Silva, André Talvani Pedrosa da, Brandão, Geraldo Célio, Cosenza, Gustavo Pereira, Queiroz, Karina Barbosa de, Costa, Daniela Caldeira
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UFOP
• Texto Completo: http://www.repositorio.ufop.br/handle/123456789/11981; https://doi.org/10.1016/j.jff.2020.103780
• topic: Inflammation; Polyunsaturated fatty acid; Saturated fatty acid; Vegetable oils

Our goal was to carry out a comparative study to evaluate the metabolic and inflammatory effects and the redox status of commercial vegetable oils supplementation [linseed (LO), coconut (VCO), and sunflower (SO)] in metabolically healthy rats. The results found in this study showed that the LO group decreased the HOMA-IR and hepatic cholesterol, and increased the serum levels of IL-6. Supplementation with VCO increased glucose and HOMA-IR, cholesterol concentration and serum triacylglycerol (TAG). In this group, there was also an increase in TBARS. In the SO group there was a decrease in serum concentrations of cholesterol and TAG and an increase in hepatic concentration of these lipids. In addition, in the SO group there was a decrease in hepatic and sérum concentrations of IL-6 and hepatic levels of TNF, as well as a decrease in the GSH/GSSG ratio, suggesting changes in glutathione metabolism and inflammatory mediators.