Candida auris: emergence and epidemiology of a highly pathogenic yeast
Autor(a) principal: | |
---|---|
Data de Publicação: | 2017 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinical and Biomedical Research |
Texto Completo: | https://seer.ufrgs.br/index.php/hcpa/article/view/73982 |
Resumo: | Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment.Keywords: Candida auris; candidiasis; candidemia; multidrug-resistance; biofilm; epidemiology; diagnosis |
id |
UFRGS-20_e8842c1af39283ec6bba8f8215d5a893 |
---|---|
oai_identifier_str |
oai:seer.ufrgs.br:article/73982 |
network_acronym_str |
UFRGS-20 |
network_name_str |
Clinical and Biomedical Research |
repository_id_str |
|
spelling |
Candida auris: emergence and epidemiology of a highly pathogenic yeastCandida auriscandidiasiscandidemiamultidrug-resistancebiofilmepidemiologydiagnosisCandida - Categoria B01.300.381.147 B01.300.930.176Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment.Keywords: Candida auris; candidiasis; candidemia; multidrug-resistance; biofilm; epidemiology; diagnosis HCPA/FAMED/UFRGS2017-09-29info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionPeer-reviewed ArticleAvaliados por Paresapplication/pdfhttps://seer.ufrgs.br/index.php/hcpa/article/view/73982Clinical & Biomedical Research; Vol. 37 No. 3 (2017)Clinical and Biomedical Research; v. 37 n. 3 (2017)2357-9730reponame:Clinical and Biomedical Researchinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSenghttps://seer.ufrgs.br/index.php/hcpa/article/view/73982/pdfCopyright (c) 2017 Clinical and Biomedical Researchinfo:eu-repo/semantics/openAccessSantos, Paula SlompLana, Daiane Flores DallaMezzari, Adelina2022-09-13T18:48:11Zoai:seer.ufrgs.br:article/73982Revistahttps://www.seer.ufrgs.br/index.php/hcpaPUBhttps://seer.ufrgs.br/index.php/hcpa/oai||cbr@hcpa.edu.br2357-97302357-9730opendoar:2022-09-13T18:48:11Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.none.fl_str_mv |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
title |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
spellingShingle |
Candida auris: emergence and epidemiology of a highly pathogenic yeast Santos, Paula Slomp Candida auris candidiasis candidemia multidrug-resistance biofilm epidemiology diagnosis Candida - Categoria B01.300.381.147 B01.300.930.176 |
title_short |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
title_full |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
title_fullStr |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
title_full_unstemmed |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
title_sort |
Candida auris: emergence and epidemiology of a highly pathogenic yeast |
author |
Santos, Paula Slomp |
author_facet |
Santos, Paula Slomp Lana, Daiane Flores Dalla Mezzari, Adelina |
author_role |
author |
author2 |
Lana, Daiane Flores Dalla Mezzari, Adelina |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Santos, Paula Slomp Lana, Daiane Flores Dalla Mezzari, Adelina |
dc.subject.por.fl_str_mv |
Candida auris candidiasis candidemia multidrug-resistance biofilm epidemiology diagnosis Candida - Categoria B01.300.381.147 B01.300.930.176 |
topic |
Candida auris candidiasis candidemia multidrug-resistance biofilm epidemiology diagnosis Candida - Categoria B01.300.381.147 B01.300.930.176 |
description |
Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment.Keywords: Candida auris; candidiasis; candidemia; multidrug-resistance; biofilm; epidemiology; diagnosis |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-09-29 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion Peer-reviewed Article Avaliados por Pares |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/73982 |
url |
https://seer.ufrgs.br/index.php/hcpa/article/view/73982 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://seer.ufrgs.br/index.php/hcpa/article/view/73982/pdf |
dc.rights.driver.fl_str_mv |
Copyright (c) 2017 Clinical and Biomedical Research info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2017 Clinical and Biomedical Research |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
publisher.none.fl_str_mv |
HCPA/FAMED/UFRGS |
dc.source.none.fl_str_mv |
Clinical & Biomedical Research; Vol. 37 No. 3 (2017) Clinical and Biomedical Research; v. 37 n. 3 (2017) 2357-9730 reponame:Clinical and Biomedical Research instname:Universidade Federal do Rio Grande do Sul (UFRGS) instacron:UFRGS |
instname_str |
Universidade Federal do Rio Grande do Sul (UFRGS) |
instacron_str |
UFRGS |
institution |
UFRGS |
reponame_str |
Clinical and Biomedical Research |
collection |
Clinical and Biomedical Research |
repository.name.fl_str_mv |
Clinical and Biomedical Research - Universidade Federal do Rio Grande do Sul (UFRGS) |
repository.mail.fl_str_mv |
||cbr@hcpa.edu.br |
_version_ |
1750135157834121216 |