Candida auris : emergence and epidemiology of a highly pathogenic yeast
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/172562 |
Resumo: | Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment. |
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Santos, Paula SlompDalla Lana, Daiane FloresMezzari, Adelina2018-02-16T02:29:15Z20172357-9730http://hdl.handle.net/10183/172562001051300Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment.application/pdfengClinical and biomedical research. Porto Alegre. Vol. 37, n. 3 (2017), p. 247-254Candida aurisCandidíaseResistência a medicamentosCandida aurisCandidiasisCandidemiaMultidrug-resistanceBiofilmEpidemiologyDiagnosisCandida auris : emergence and epidemiology of a highly pathogenic yeastinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/otherinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSORIGINAL001051300.pdf001051300.pdfTexto completo (inglês)application/pdf814776http://www.lume.ufrgs.br/bitstream/10183/172562/1/001051300.pdf6b174e54cab85957db4a145b5c485bb6MD51TEXT001051300.pdf.txt001051300.pdf.txtExtracted Texttext/plain37118http://www.lume.ufrgs.br/bitstream/10183/172562/2/001051300.pdf.txt83e0175aca5c88939c21f45530de342bMD52THUMBNAIL001051300.pdf.jpg001051300.pdf.jpgGenerated Thumbnailimage/jpeg1884http://www.lume.ufrgs.br/bitstream/10183/172562/3/001051300.pdf.jpg2f6788c86d43d7352684270572e8a5d8MD5310183/1725622023-06-25 03:42:09.892501oai:www.lume.ufrgs.br:10183/172562Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-06-25T06:42:09Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
title |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
spellingShingle |
Candida auris : emergence and epidemiology of a highly pathogenic yeast Santos, Paula Slomp Candida auris Candidíase Resistência a medicamentos Candida auris Candidiasis Candidemia Multidrug-resistance Biofilm Epidemiology Diagnosis |
title_short |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
title_full |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
title_fullStr |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
title_full_unstemmed |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
title_sort |
Candida auris : emergence and epidemiology of a highly pathogenic yeast |
author |
Santos, Paula Slomp |
author_facet |
Santos, Paula Slomp Dalla Lana, Daiane Flores Mezzari, Adelina |
author_role |
author |
author2 |
Dalla Lana, Daiane Flores Mezzari, Adelina |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Santos, Paula Slomp Dalla Lana, Daiane Flores Mezzari, Adelina |
dc.subject.por.fl_str_mv |
Candida auris Candidíase Resistência a medicamentos |
topic |
Candida auris Candidíase Resistência a medicamentos Candida auris Candidiasis Candidemia Multidrug-resistance Biofilm Epidemiology Diagnosis |
dc.subject.eng.fl_str_mv |
Candida auris Candidiasis Candidemia Multidrug-resistance Biofilm Epidemiology Diagnosis |
description |
Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including Brazil. C. auris affects mainly inpatients, patients in intensive care units, exposed to broad-spectrum antifungal medications and who make use of vascular catheters. Currently, this yeast is one of the main responsible for invasive infections in hospitals and has been cause of concern by authorities and organs due to its rapid dissemination and difficult treatment caused by its low susceptibility to antifungal agents traditionally used in clinical practice. As a contributor to the severity of infections associated with C. auris, the transmission mechanism is still unknown, which implies in a lack of control of the microorganism and high mortality rates. Thus, this literature review presents relevant information in order to alert the importance of C. auris as an etiological agent of systemic infections, as well as its epidemiology and the real challenges of the treatment. |
publishDate |
2017 |
dc.date.issued.fl_str_mv |
2017 |
dc.date.accessioned.fl_str_mv |
2018-02-16T02:29:15Z |
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2357-9730 |
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dc.relation.ispartof.pt_BR.fl_str_mv |
Clinical and biomedical research. Porto Alegre. Vol. 37, n. 3 (2017), p. 247-254 |
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