Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UFRGS |
Texto Completo: | http://hdl.handle.net/10183/257241 |
Resumo: | Introduction: The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. Methods and analysis: A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed. |
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Costa, Maria LauraCosta, Sergio Hofmeister de Almeida MartinsVettorazzi, JaneteCecatti, Jose GuilhermeREBRACO Study Group2023-04-19T03:26:52Z20212044-6055http://hdl.handle.net/10183/257241001164709Introduction: The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. Methods and analysis: A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed.application/pdfengBMJ open. London. Vol. 11, no. 12 (2021), e051284, 15 p.COVID-19GravidezPeríodo pós-partoVitamina DNascido vivoNatimortoBrazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocolEstrangeiroinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UFRGSinstname:Universidade Federal do Rio Grande do Sul (UFRGS)instacron:UFRGSTEXT001164709.pdf.txt001164709.pdf.txtExtracted Texttext/plain85573http://www.lume.ufrgs.br/bitstream/10183/257241/3/001164709.pdf.txte453ce7f5f4aa25c7c27bb3804e01a7fMD53001164709-02.pdf.txt001164709-02.pdf.txtExtracted Texttext/plain261810http://www.lume.ufrgs.br/bitstream/10183/257241/4/001164709-02.pdf.txt57c7bb95f5fb8170c2df87e72b6ac0ceMD54ORIGINAL001164709.pdfTexto completo (inglês)application/pdf1438310http://www.lume.ufrgs.br/bitstream/10183/257241/1/001164709.pdfd14906025b2c62e5294f2ab530edcfddMD51001164709-02.pdfMaterial suplementarapplication/pdf364815http://www.lume.ufrgs.br/bitstream/10183/257241/2/001164709-02.pdfb7b1446eb41640e13c30b4388da4c2f3MD5210183/2572412023-04-20 03:22:41.681327oai:www.lume.ufrgs.br:10183/257241Repositório de PublicaçõesPUBhttps://lume.ufrgs.br/oai/requestopendoar:2023-04-20T06:22:41Repositório Institucional da UFRGS - Universidade Federal do Rio Grande do Sul (UFRGS)false |
dc.title.pt_BR.fl_str_mv |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
title |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
spellingShingle |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol Costa, Maria Laura COVID-19 Gravidez Período pós-parto Vitamina D Nascido vivo Natimorto |
title_short |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
title_full |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
title_fullStr |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
title_full_unstemmed |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
title_sort |
Brazilian network of COVID-19 during pregnancy (REBRACO) : a multicentre study protocol |
author |
Costa, Maria Laura |
author_facet |
Costa, Maria Laura Costa, Sergio Hofmeister de Almeida Martins Vettorazzi, Janete Cecatti, Jose Guilherme REBRACO Study Group |
author_role |
author |
author2 |
Costa, Sergio Hofmeister de Almeida Martins Vettorazzi, Janete Cecatti, Jose Guilherme REBRACO Study Group |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Costa, Maria Laura Costa, Sergio Hofmeister de Almeida Martins Vettorazzi, Janete Cecatti, Jose Guilherme REBRACO Study Group |
dc.subject.por.fl_str_mv |
COVID-19 Gravidez Período pós-parto Vitamina D Nascido vivo Natimorto |
topic |
COVID-19 Gravidez Período pós-parto Vitamina D Nascido vivo Natimorto |
description |
Introduction: The aim of this study was to evaluate the clinical, epidemiological and laboratory aspects of SARS-CoV-2 infection during pregnancy and postpartum in 16 maternity hospitals. Methods and analysis: A prospective multicentre study, with five axes. First, the prevalence of SARS-CoV-2 infection among women admitted for childbirth will be described in a cross-sectional study. Second, maternal and perinatal outcomes will be assessed in a prospective cohort study including pregnant or postpartum women with suspected COVID-19. Third, a cohort of positive COVID-19 cases with sampling of a variety of biological material. Histopathological and viral analysis of biological maternal and neonatal samples will be performed, and the assessment of nutritional variables to evaluate the association between vitamin D and severity of infection. Fourth, a monitoring and evaluation committee to collect relevant healthcare information and plan actions in centres facing the pandemic. Furthermore, qualitative studies will be performed to study pregnant women, their families and health professionals. Fifth, an ecological study will monitor the number of live births, stillbirths and other outcomes to explore any trend among the periods before, during and after the pandemic. Data will systematically be collected in an electronic platform following standardised operational procedures. For quantitative study components, an appropriate statistical approach will be used for each analysis. For qualitative data, in-depth interviews recorded in audio will be transcribed, checking the text obtained with the recording. Subsequently, thematic analysis with the aid of the NVivo programme will be performed. |
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2021 |
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2021 |
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BMJ open. London. Vol. 11, no. 12 (2021), e051284, 15 p. |
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