Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es

Detalhes bibliográficos
Autor(a) principal: Fazio Junior, Pedro Ivan
Data de Publicação: 2012
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRRJ
Texto Completo: https://tede.ufrrj.br/jspui/handle/jspui/2903
Resumo: The objective of this study was to evaluate the efficacy of a collar impregnated with flumethrin (2.5%) and propoxur (10%) against adults of Ctenocephalides felis felis and Rhipicephalus sanguineus on Beagle dogs, and to evaluate possible changes in serum cholinesterase (butyrylcholinesterase) after the use of the collar. Twenty Beagle dogs were divided into two groups, on 10 animals impregnated collars were placed and the other 10 remained untreated (control group). Each dog was infested with 50 pairs of C. felis felis and 25 pairs of R. sanguineus weekly during the first month, and after the second month every two weeks until day +210. Forty-eight hours after infestation, live fleas and ticks were recovered and counted from the animals. For determination of serum cholinesterase, blood samples were collected on days -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 and +210. All animals were evaluated weekly for signs consistent with clinical intoxication. At the end of the trial, the collars were removed, and after seven days, new measurement of cholinesterase was done. . The efficacy for C. felis felis was over 80% for up to day +168 after treatment. The efficacy for R. sanguineus was over 80% up to day +182. It was found that the collar has not decreased significantly (p ? 0.05) serum butyrylcholinesterase in dogs by comparing the means before and after treatment, however, the serum cholinesterase activity was significantly increased (p ? 0.05) after removal of the collars. It was evident that the impregnated with propoxur and flumethrin has an efficacy superior to five months in the control of C. felis felis and R. sanguineus. The alteration in serum cholinesterase levels by propoxur was not relevant and no signs of toxicity were observed during the experimental period
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spelling Coumendouros, Katherina006.846.627-79http://lattes.cnpq.br/6886641792170591Fernandes, Julio IsraelSouza, Clarissa Pimentel deAzevedo, Tha?s Ribeiro Correia112.780.737-44http://lattes.cnpq.br/2399464111506427Fazio Junior, Pedro Ivan2019-09-19T14:08:15Z2012-02-23FAZIO JUNIOR, Pedro Ivan. Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es. 2012. 48 f. Disserta??o (Programa de P?s-Gradua??o em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica.https://tede.ufrrj.br/jspui/handle/jspui/2903The objective of this study was to evaluate the efficacy of a collar impregnated with flumethrin (2.5%) and propoxur (10%) against adults of Ctenocephalides felis felis and Rhipicephalus sanguineus on Beagle dogs, and to evaluate possible changes in serum cholinesterase (butyrylcholinesterase) after the use of the collar. Twenty Beagle dogs were divided into two groups, on 10 animals impregnated collars were placed and the other 10 remained untreated (control group). Each dog was infested with 50 pairs of C. felis felis and 25 pairs of R. sanguineus weekly during the first month, and after the second month every two weeks until day +210. Forty-eight hours after infestation, live fleas and ticks were recovered and counted from the animals. For determination of serum cholinesterase, blood samples were collected on days -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 and +210. All animals were evaluated weekly for signs consistent with clinical intoxication. At the end of the trial, the collars were removed, and after seven days, new measurement of cholinesterase was done. . The efficacy for C. felis felis was over 80% for up to day +168 after treatment. The efficacy for R. sanguineus was over 80% up to day +182. It was found that the collar has not decreased significantly (p ? 0.05) serum butyrylcholinesterase in dogs by comparing the means before and after treatment, however, the serum cholinesterase activity was significantly increased (p ? 0.05) after removal of the collars. It was evident that the impregnated with propoxur and flumethrin has an efficacy superior to five months in the control of C. felis felis and R. sanguineus. The alteration in serum cholinesterase levels by propoxur was not relevant and no signs of toxicity were observed during the experimental periodO objetivo deste trabalho foi avaliar a efic?cia de uma coleira impregnada com Flumetrina (2,5%) e Propoxur (10%) sobre adultos de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es Beagle com avalia??o de poss?veis altera??es da colinesterase s?rica (butirilcolinesterase) ap?s o uso da coleira. Para isso foram utilizados 20 c?es da ra?a Beagle, divididos em dois grupos, onde em 10 animais foram colocadas as coleiras impregnadas e os outros 10 sem nenhum tratamento (controle). Cada c?o foi infestado com 50 casais de C. felis felis e 25 casais de R. sanguineus semanalmente no primeiro m?s e a partir do segundo m?s quinzenalmente at? o dia +210. Quarenta e oito horas ap?s as infesta??es foram realizadas avalia??es com contagem de pulgas e carrapatos vivos recuperados nos animais. Para dosagem da colinesterase s?rica foram coletadas amostras de sangue dos animais nos dias -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 e +210. Todos os animais foram avaliados semanalmente em rela??o a sinais cl?nicos compat?veis com intoxica??o. Posteriormente ao t?rmino do experimento de efic?cia as coleiras foram removidas e ap?s sete dias foi realizada nova dosagem da colinesterase. A efic?cia para C. felis felis foi superior a 80% at? o dia +168 ap?s tratamento. A efic?cia para R. sanguineus foi superior a 80% at? o dia +182. Foi verificado que a coleira n?o diminuiu significativamente (p?0,05) os n?veis s?ricos de butirilcolinesterase nos c?es comparando-se as m?dias antes e ap?s o tratamento, no entanto, a atividade s?rica da colinesterase aumentou significativamente (p?0,05) ap?s a retirada da coleira. Evidenciou-se que a coleira a base de propoxur e flumetrina apresenta efic?cia superior a cinco meses sobre C. felis felis e R. sanguineus. A altera??o da colinesterase s?rica dos animais pelo propoxur n?o foi relevante e nenhum sinal de toxicidade foi observado durante o per?odo experimentalSubmitted by Celso Magalhaes (celsomagalhaes@ufrrj.br) on 2019-09-19T14:08:15Z No. of bitstreams: 1 2012 - Pedro Ivan Fazio Junior.pdf: 1016463 bytes, checksum: 14de6b5137318bd0cc0e573e49d00fcb (MD5)Made available in DSpace on 2019-09-19T14:08:15Z (GMT). No. of bitstreams: 1 2012 - Pedro Ivan Fazio Junior.pdf: 1016463 bytes, checksum: 14de6b5137318bd0cc0e573e49d00fcb (MD5) Previous issue date: 2012-02-23Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico - CNPQapplication/pdfhttps://tede.ufrrj.br/retrieve/10661/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/16222/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/22526/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/28904/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/35488/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/41886/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/47498/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpghttps://tede.ufrrj.br/retrieve/53836/2012%20-%20Pedro%20Ivan%20Fazio%20Junior.pdf.jpgporUniversidade Federal Rural do Rio de JaneiroPrograma de P?s-Gradua??o em Ci?ncias Veterin?riasUFRRJBrasilInstituto de Veterin?riaABDELKADER, S. 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W.; WHITACRE, D. M. An Introduction to Insecticides (4th edition), 2009. Dispon?vel em: <http://ipmworld.umn.edu/chapters/ware.htm>. Acesso em: 09 dez. 2011. WINGFIELD, W. E. Segredos em Medicina Veterin?ria. Porto Alegre: Artmed, 1998. 546 p. WITCHEY-LAKSHMANAN, L. C. Long-acting control of ectoparasites: a review of collar technologies for companion animals. 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dc.title.por.fl_str_mv Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
dc.title.alternative.eng.fl_str_mv Clinical evaluation and efficacy of a collar containing flumethrin and propoxur in the control of Ctenocephalides felis felis and Rhipicephalus sanguineus in dogs
title Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
spellingShingle Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
Fazio Junior, Pedro Ivan
Pulgas
Carrapatos
Butirilcolinesterase
Fleas
Ticks
Butyrylcholinesterase
Medicina Veterin?ria
title_short Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
title_full Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
title_fullStr Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
title_full_unstemmed Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
title_sort Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es
author Fazio Junior, Pedro Ivan
author_facet Fazio Junior, Pedro Ivan
author_role author
dc.contributor.advisor1.fl_str_mv Coumendouros, Katherina
dc.contributor.advisor1ID.fl_str_mv 006.846.627-79
dc.contributor.advisor1Lattes.fl_str_mv http://lattes.cnpq.br/6886641792170591
dc.contributor.referee1.fl_str_mv Fernandes, Julio Israel
dc.contributor.referee2.fl_str_mv Souza, Clarissa Pimentel de
dc.contributor.referee3.fl_str_mv Azevedo, Tha?s Ribeiro Correia
dc.contributor.authorID.fl_str_mv 112.780.737-44
dc.contributor.authorLattes.fl_str_mv http://lattes.cnpq.br/2399464111506427
dc.contributor.author.fl_str_mv Fazio Junior, Pedro Ivan
contributor_str_mv Coumendouros, Katherina
Fernandes, Julio Israel
Souza, Clarissa Pimentel de
Azevedo, Tha?s Ribeiro Correia
dc.subject.por.fl_str_mv Pulgas
Carrapatos
Butirilcolinesterase
topic Pulgas
Carrapatos
Butirilcolinesterase
Fleas
Ticks
Butyrylcholinesterase
Medicina Veterin?ria
dc.subject.eng.fl_str_mv Fleas
Ticks
Butyrylcholinesterase
dc.subject.cnpq.fl_str_mv Medicina Veterin?ria
description The objective of this study was to evaluate the efficacy of a collar impregnated with flumethrin (2.5%) and propoxur (10%) against adults of Ctenocephalides felis felis and Rhipicephalus sanguineus on Beagle dogs, and to evaluate possible changes in serum cholinesterase (butyrylcholinesterase) after the use of the collar. Twenty Beagle dogs were divided into two groups, on 10 animals impregnated collars were placed and the other 10 remained untreated (control group). Each dog was infested with 50 pairs of C. felis felis and 25 pairs of R. sanguineus weekly during the first month, and after the second month every two weeks until day +210. Forty-eight hours after infestation, live fleas and ticks were recovered and counted from the animals. For determination of serum cholinesterase, blood samples were collected on days -14, -7, +1, +5, +10, +30, +45, +60, +75, +90, +105, +120, +135, +150, +165, +180, +195 and +210. All animals were evaluated weekly for signs consistent with clinical intoxication. At the end of the trial, the collars were removed, and after seven days, new measurement of cholinesterase was done. . The efficacy for C. felis felis was over 80% for up to day +168 after treatment. The efficacy for R. sanguineus was over 80% up to day +182. It was found that the collar has not decreased significantly (p ? 0.05) serum butyrylcholinesterase in dogs by comparing the means before and after treatment, however, the serum cholinesterase activity was significantly increased (p ? 0.05) after removal of the collars. It was evident that the impregnated with propoxur and flumethrin has an efficacy superior to five months in the control of C. felis felis and R. sanguineus. The alteration in serum cholinesterase levels by propoxur was not relevant and no signs of toxicity were observed during the experimental period
publishDate 2012
dc.date.issued.fl_str_mv 2012-02-23
dc.date.accessioned.fl_str_mv 2019-09-19T14:08:15Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.citation.fl_str_mv FAZIO JUNIOR, Pedro Ivan. Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es. 2012. 48 f. Disserta??o (Programa de P?s-Gradua??o em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica.
dc.identifier.uri.fl_str_mv https://tede.ufrrj.br/jspui/handle/jspui/2903
identifier_str_mv FAZIO JUNIOR, Pedro Ivan. Avalia??o cl?nica e efic?cia de uma coleira contendo flumetrina e propoxur no controle de Ctenocephalides felis felis e Rhipicephalus sanguineus em c?es. 2012. 48 f. Disserta??o (Programa de P?s-Gradua??o em Ci?ncias Veterin?rias) - Universidade Federal Rural do Rio de Janeiro, Serop?dica.
url https://tede.ufrrj.br/jspui/handle/jspui/2903
dc.language.iso.fl_str_mv por
language por
dc.relation.references.por.fl_str_mv ABDELKADER, S. V.; HAUGE, J. G. Serum determination in the study of liver disease in dogs. Acta Veterin?ria Scandinavica, v. 27, n. 1, p.50-79, 1986. ADAMS, H. R. Farmacologia e terap?utica em veterin?ria. 8. ed. Rio de Janeiro: Guanabara Koogan, 2003. 1034 p. AGRAWAL, V. K.; AGARWAL, A.; CHOUDHARY, V.; SINGH, R.; AHMED, N.; SHARMA, M.; NARULA, K.; AGRAWAL, P. Efficacy of imidacloprid and fipronil gels over synthetic pyrethroid and propoxur aerosols in control of German cockroaches (Dictyoptera: Blatellidae). Journal of Vector Borne Disease. v. 47, n. 1, p. 39-44, 2010. AHRENS, F. A. Farmacologia Veterin?ria. Porto Alegre: Artes M?dicas, 1997. 360 p. ALAHMED, A. M.; HUSSEIN, H. I.; KHEIR, S. M.; AL-RAJHY, D. Efficacy of flumethrin and coumaphos against the camel tick Hyalomma dromedarii L. (Acari: Ixodidae). Journal of the Egyptian Society of Parasitology, v. 31, n. 3, p. 791-798, 2001. ALONZO, H. G. A.; CORR?A, C. I. Praguicidas. In: OGA, S.. 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repository.name.fl_str_mv Biblioteca Digital de Teses e Dissertações da UFRRJ - Universidade Federal Rural do Rio de Janeiro (UFRRJ)
repository.mail.fl_str_mv bibliot@ufrrj.br||bibliot@ufrrj.br
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