Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy
Autor(a) principal: | |
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Data de Publicação: | 2012 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/35302 http://dx.doi.org/10.1016/j.seizure.2012.06.002 |
Resumo: | Purpose: Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluation. A major concern in epilepsy surgery is whether to consider CAH treatment in patients with psychosis of epilepsy (POE). This study analyzed the safety and adverse events (AEs) of VEEG monitoring and the post-surgical outcomes of patients with refractory TLE-MTS and POE who underwent CAH.Method: Clinical, sociodemographic and VEEG data from 18 patients with TLE-MTS and POE were analyzed. Psychiatric evaluations were performed using DSM-IV and ILAE criteria. the seizure outcome was evaluated using Engel's criteria.Results: Two patients (11.2%) presented AEs that did not result in increased lengths of hospitalization. of the 10 patients (55.5%) who underwent CAH, 6 (60%) became free of disabling seizures (Engel I). the psychiatric and QOL evaluations revealed improvements of psychotic symptoms (p = 0.01) and in Physical Health (p = 0.01) following surgery.Conclusion: These data reinforce that VEEG monitoring is a safe method to evaluate patients with refractory TLE-MTS and POE in epilepsy centers. (C) 2012 British Epilepsy Association. Published by Elsevier B.V. All rights reserved. |
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Conceição, Priscila Oliveira da [UNIFESP]Araujo Filho, Gerardo Maria de [UNIFESP]Mazetto, Lenon [UNIFESP]Alonso, Neide Barreira [UNIFESP]Yacubian, Elza Márcia Targas [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2016-01-24T14:27:44Z2016-01-24T14:27:44Z2012-10-01Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 21, n. 8, p. 583-587, 2012.1059-1311http://repositorio.unifesp.br/handle/11600/35302http://dx.doi.org/10.1016/j.seizure.2012.06.002WOS000308628500005.pdf10.1016/j.seizure.2012.06.002WOS:000308628500005Purpose: Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluation. A major concern in epilepsy surgery is whether to consider CAH treatment in patients with psychosis of epilepsy (POE). This study analyzed the safety and adverse events (AEs) of VEEG monitoring and the post-surgical outcomes of patients with refractory TLE-MTS and POE who underwent CAH.Method: Clinical, sociodemographic and VEEG data from 18 patients with TLE-MTS and POE were analyzed. Psychiatric evaluations were performed using DSM-IV and ILAE criteria. the seizure outcome was evaluated using Engel's criteria.Results: Two patients (11.2%) presented AEs that did not result in increased lengths of hospitalization. of the 10 patients (55.5%) who underwent CAH, 6 (60%) became free of disabling seizures (Engel I). the psychiatric and QOL evaluations revealed improvements of psychotic symptoms (p = 0.01) and in Physical Health (p = 0.01) following surgery.Conclusion: These data reinforce that VEEG monitoring is a safe method to evaluate patients with refractory TLE-MTS and POE in epilepsy centers. (C) 2012 British Epilepsy Association. Published by Elsevier B.V. All rights reserved.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Universidade Federal de São Paulo UNIFESP, Dept Neurol & Neurosurg, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, LiNC, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Neurol & Neurosurg, São Paulo, BrazilUniversidade Federal de São Paulo UNIFESP, Dept Psychiat, LiNC, São Paulo, BrazilWeb of Science583-587engW B Saunders Co LtdSeizure-european Journal of EpilepsyMesial temporal sclerosisPsychoses of epilepsyVideo-EEG monitoringSurgical outcomeSafety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsyinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALWOS000308628500005.pdfapplication/pdf243963${dspace.ui.url}/bitstream/11600/35302/1/WOS000308628500005.pdf719d00b1414f26d42b5dad8f4a3d8c0fMD51open accessTEXTWOS000308628500005.pdf.txtWOS000308628500005.pdf.txtExtracted texttext/plain26305${dspace.ui.url}/bitstream/11600/35302/2/WOS000308628500005.pdf.txte9b0a1933ec539a34816cda26600b5dfMD52open access11600/353022021-09-30 11:04:14.305open accessoai:repositorio.unifesp.br:11600/35302Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:10:50.333957Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
title |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
spellingShingle |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy Conceição, Priscila Oliveira da [UNIFESP] Mesial temporal sclerosis Psychoses of epilepsy Video-EEG monitoring Surgical outcome |
title_short |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
title_full |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
title_fullStr |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
title_full_unstemmed |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
title_sort |
Safety of video-EEG monitoring and surgical outcome in patients with mesial temporal sclerosis and psychosis of epilepsy |
author |
Conceição, Priscila Oliveira da [UNIFESP] |
author_facet |
Conceição, Priscila Oliveira da [UNIFESP] Araujo Filho, Gerardo Maria de [UNIFESP] Mazetto, Lenon [UNIFESP] Alonso, Neide Barreira [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
author_role |
author |
author2 |
Araujo Filho, Gerardo Maria de [UNIFESP] Mazetto, Lenon [UNIFESP] Alonso, Neide Barreira [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
author2_role |
author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Conceição, Priscila Oliveira da [UNIFESP] Araujo Filho, Gerardo Maria de [UNIFESP] Mazetto, Lenon [UNIFESP] Alonso, Neide Barreira [UNIFESP] Yacubian, Elza Márcia Targas [UNIFESP] |
dc.subject.eng.fl_str_mv |
Mesial temporal sclerosis Psychoses of epilepsy Video-EEG monitoring Surgical outcome |
topic |
Mesial temporal sclerosis Psychoses of epilepsy Video-EEG monitoring Surgical outcome |
description |
Purpose: Cortico-amygdalohippocampectomy (CAH) has become an important treatment option for patients with refractory temporal lobe epilepsy and mesial temporal sclerosis (TLE-MTS); it has resulted in a 60-70% seizure remission rate and significant quality of life (QOL) improvements. Video-electroencephalography (VEEG) monitoring has been widely used in epilepsy centers for pre-surgical evaluation. A major concern in epilepsy surgery is whether to consider CAH treatment in patients with psychosis of epilepsy (POE). This study analyzed the safety and adverse events (AEs) of VEEG monitoring and the post-surgical outcomes of patients with refractory TLE-MTS and POE who underwent CAH.Method: Clinical, sociodemographic and VEEG data from 18 patients with TLE-MTS and POE were analyzed. Psychiatric evaluations were performed using DSM-IV and ILAE criteria. the seizure outcome was evaluated using Engel's criteria.Results: Two patients (11.2%) presented AEs that did not result in increased lengths of hospitalization. of the 10 patients (55.5%) who underwent CAH, 6 (60%) became free of disabling seizures (Engel I). the psychiatric and QOL evaluations revealed improvements of psychotic symptoms (p = 0.01) and in Physical Health (p = 0.01) following surgery.Conclusion: These data reinforce that VEEG monitoring is a safe method to evaluate patients with refractory TLE-MTS and POE in epilepsy centers. (C) 2012 British Epilepsy Association. Published by Elsevier B.V. All rights reserved. |
publishDate |
2012 |
dc.date.issued.fl_str_mv |
2012-10-01 |
dc.date.accessioned.fl_str_mv |
2016-01-24T14:27:44Z |
dc.date.available.fl_str_mv |
2016-01-24T14:27:44Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 21, n. 8, p. 583-587, 2012. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/35302 http://dx.doi.org/10.1016/j.seizure.2012.06.002 |
dc.identifier.issn.none.fl_str_mv |
1059-1311 |
dc.identifier.file.none.fl_str_mv |
WOS000308628500005.pdf |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.seizure.2012.06.002 |
dc.identifier.wos.none.fl_str_mv |
WOS:000308628500005 |
identifier_str_mv |
Seizure-european Journal of Epilepsy. London: W B Saunders Co Ltd, v. 21, n. 8, p. 583-587, 2012. 1059-1311 WOS000308628500005.pdf 10.1016/j.seizure.2012.06.002 WOS:000308628500005 |
url |
http://repositorio.unifesp.br/handle/11600/35302 http://dx.doi.org/10.1016/j.seizure.2012.06.002 |
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eng |
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Seizure-european Journal of Epilepsy |
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openAccess |
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583-587 |
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W B Saunders Co Ltd |
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W B Saunders Co Ltd |
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