Body composition and lipodystrophy in prepubertal HIV-infected children
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNIFESP |
Texto Completo: | http://repositorio.unifesp.br/handle/11600/7617 http://dx.doi.org/10.1016/j.bjid.2012.12.001 |
Resumo: | OBJECTIVE: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. METHODS: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care Center of the Division of Pediatric Infectious Diseases - Universidade Federal de São Paulo (UNIFESP), São Paulo city, Brazil, was carried out from August to December 2008. Age, clinical and immunological status, prophylaxis, transmission and highly active antiretroviral therapy were recorded. Body mass index z-score and height-for-age z-score were calculated to characterize the nutritional status. Circumferences were measured with flexible tape and skinfolds were assessed by an adipometry. Fat mass and lean mass were determined by dual-energy X-ray absorptiometry. Presence of clinical signs of lipodystrophy was assessed by a trained clinician. Data were analyzed using SPSS 12.0 software. RESULTS: The mean age and standard deviation were 9.8 (1.2) years, 50% were girls and 82.5% children from B and C categories. Clinical lipodystrophy and dislypidemia were present in 27.5% and 70%, respectively. The trunk to arm ratio and the limb to trunk ratio had positive association with lipodystrophy. Patients with lipodystrophy had short stature, higher triglycerides values and lower HDL-cholesterol. CONCLUSION: The ratios obtained by skinfolds and dual-energy X-ray absorptiometry measurements can be considered as indicators of preclinical lipodystrophy. The cutoff points have not been determined yet; however, continuous assessment may be useful to identify early body composition changes. |
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Palchetti, Cecília Zanin [UNIFESP]Patin, Rose Vega [UNIFESP]Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP]Szejnfeld, Vera Lucia [UNIFESP]Succi, Regina Célia de Menezes [UNIFESP]Oliveira, Fernanda Luisa Ceragioli [UNIFESP]Universidade Federal de São Paulo (UNIFESP)2015-06-14T13:45:17Z2015-06-14T13:45:17Z2013-02-01Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 17, n. 1, p. 01-06, 2013.1413-8670http://repositorio.unifesp.br/handle/11600/7617http://dx.doi.org/10.1016/j.bjid.2012.12.001S1413-86702013000100001.pdfS1413-8670201300010000110.1016/j.bjid.2012.12.001WOS:000315068200001OBJECTIVE: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. METHODS: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care Center of the Division of Pediatric Infectious Diseases - Universidade Federal de São Paulo (UNIFESP), São Paulo city, Brazil, was carried out from August to December 2008. Age, clinical and immunological status, prophylaxis, transmission and highly active antiretroviral therapy were recorded. Body mass index z-score and height-for-age z-score were calculated to characterize the nutritional status. Circumferences were measured with flexible tape and skinfolds were assessed by an adipometry. Fat mass and lean mass were determined by dual-energy X-ray absorptiometry. Presence of clinical signs of lipodystrophy was assessed by a trained clinician. Data were analyzed using SPSS 12.0 software. RESULTS: The mean age and standard deviation were 9.8 (1.2) years, 50% were girls and 82.5% children from B and C categories. Clinical lipodystrophy and dislypidemia were present in 27.5% and 70%, respectively. The trunk to arm ratio and the limb to trunk ratio had positive association with lipodystrophy. Patients with lipodystrophy had short stature, higher triglycerides values and lower HDL-cholesterol. CONCLUSION: The ratios obtained by skinfolds and dual-energy X-ray absorptiometry measurements can be considered as indicators of preclinical lipodystrophy. The cutoff points have not been determined yet; however, continuous assessment may be useful to identify early body composition changes.Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUNIFESP, EPMSciELO01-06engBrazilian Society of Infectious DiseasesBrazilian Journal of Infectious DiseasesHIVChildLipodystrophyBody compositionAnthropometryBody composition and lipodystrophy in prepubertal HIV-infected childreninfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleinfo:eu-repo/semantics/openAccessreponame:Repositório Institucional da UNIFESPinstname:Universidade Federal de São Paulo (UNIFESP)instacron:UNIFESPORIGINALS1413-86702013000100001.pdfapplication/pdf229422${dspace.ui.url}/bitstream/11600/7617/1/S1413-86702013000100001.pdff904e9713c3c3282bccdf9908f9ed46eMD51open accessTEXTS1413-86702013000100001.pdf.txtS1413-86702013000100001.pdf.txtExtracted texttext/plain30454${dspace.ui.url}/bitstream/11600/7617/2/S1413-86702013000100001.pdf.txt7b5cf49c0e4c926b5bfd3c5d61a7bbeeMD52open access11600/76172022-07-08 10:54:13.882open accessoai:repositorio.unifesp.br:11600/7617Repositório InstitucionalPUBhttp://www.repositorio.unifesp.br/oai/requestopendoar:34652023-05-25T12:21:26.852490Repositório Institucional da UNIFESP - Universidade Federal de São Paulo (UNIFESP)false |
dc.title.en.fl_str_mv |
Body composition and lipodystrophy in prepubertal HIV-infected children |
title |
Body composition and lipodystrophy in prepubertal HIV-infected children |
spellingShingle |
Body composition and lipodystrophy in prepubertal HIV-infected children Palchetti, Cecília Zanin [UNIFESP] HIV Child Lipodystrophy Body composition Anthropometry |
title_short |
Body composition and lipodystrophy in prepubertal HIV-infected children |
title_full |
Body composition and lipodystrophy in prepubertal HIV-infected children |
title_fullStr |
Body composition and lipodystrophy in prepubertal HIV-infected children |
title_full_unstemmed |
Body composition and lipodystrophy in prepubertal HIV-infected children |
title_sort |
Body composition and lipodystrophy in prepubertal HIV-infected children |
author |
Palchetti, Cecília Zanin [UNIFESP] |
author_facet |
Palchetti, Cecília Zanin [UNIFESP] Patin, Rose Vega [UNIFESP] Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP] Szejnfeld, Vera Lucia [UNIFESP] Succi, Regina Célia de Menezes [UNIFESP] Oliveira, Fernanda Luisa Ceragioli [UNIFESP] |
author_role |
author |
author2 |
Patin, Rose Vega [UNIFESP] Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP] Szejnfeld, Vera Lucia [UNIFESP] Succi, Regina Célia de Menezes [UNIFESP] Oliveira, Fernanda Luisa Ceragioli [UNIFESP] |
author2_role |
author author author author author |
dc.contributor.institution.none.fl_str_mv |
Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Palchetti, Cecília Zanin [UNIFESP] Patin, Rose Vega [UNIFESP] Gouvêa, Aida de Fátima Thomé Barbosa [UNIFESP] Szejnfeld, Vera Lucia [UNIFESP] Succi, Regina Célia de Menezes [UNIFESP] Oliveira, Fernanda Luisa Ceragioli [UNIFESP] |
dc.subject.eng.fl_str_mv |
HIV Child Lipodystrophy Body composition Anthropometry |
topic |
HIV Child Lipodystrophy Body composition Anthropometry |
description |
OBJECTIVE: To identify lipodystrophy in prepubertal HIV-infected children using anthropometric parameters and body composition assessment. METHODS: Cross-sectional study including 40 prepubertal HIV-infected children of both genders seen at the Care Center of the Division of Pediatric Infectious Diseases - Universidade Federal de São Paulo (UNIFESP), São Paulo city, Brazil, was carried out from August to December 2008. Age, clinical and immunological status, prophylaxis, transmission and highly active antiretroviral therapy were recorded. Body mass index z-score and height-for-age z-score were calculated to characterize the nutritional status. Circumferences were measured with flexible tape and skinfolds were assessed by an adipometry. Fat mass and lean mass were determined by dual-energy X-ray absorptiometry. Presence of clinical signs of lipodystrophy was assessed by a trained clinician. Data were analyzed using SPSS 12.0 software. RESULTS: The mean age and standard deviation were 9.8 (1.2) years, 50% were girls and 82.5% children from B and C categories. Clinical lipodystrophy and dislypidemia were present in 27.5% and 70%, respectively. The trunk to arm ratio and the limb to trunk ratio had positive association with lipodystrophy. Patients with lipodystrophy had short stature, higher triglycerides values and lower HDL-cholesterol. CONCLUSION: The ratios obtained by skinfolds and dual-energy X-ray absorptiometry measurements can be considered as indicators of preclinical lipodystrophy. The cutoff points have not been determined yet; however, continuous assessment may be useful to identify early body composition changes. |
publishDate |
2013 |
dc.date.issued.fl_str_mv |
2013-02-01 |
dc.date.accessioned.fl_str_mv |
2015-06-14T13:45:17Z |
dc.date.available.fl_str_mv |
2015-06-14T13:45:17Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.citation.fl_str_mv |
Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 17, n. 1, p. 01-06, 2013. |
dc.identifier.uri.fl_str_mv |
http://repositorio.unifesp.br/handle/11600/7617 http://dx.doi.org/10.1016/j.bjid.2012.12.001 |
dc.identifier.issn.none.fl_str_mv |
1413-8670 |
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S1413-86702013000100001.pdf |
dc.identifier.scielo.none.fl_str_mv |
S1413-86702013000100001 |
dc.identifier.doi.none.fl_str_mv |
10.1016/j.bjid.2012.12.001 |
dc.identifier.wos.none.fl_str_mv |
WOS:000315068200001 |
identifier_str_mv |
Brazilian Journal of Infectious Diseases. Brazilian Society of Infectious Diseases, v. 17, n. 1, p. 01-06, 2013. 1413-8670 S1413-86702013000100001.pdf S1413-86702013000100001 10.1016/j.bjid.2012.12.001 WOS:000315068200001 |
url |
http://repositorio.unifesp.br/handle/11600/7617 http://dx.doi.org/10.1016/j.bjid.2012.12.001 |
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eng |
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Brazilian Journal of Infectious Diseases |
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openAccess |
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01-06 |
dc.publisher.none.fl_str_mv |
Brazilian Society of Infectious Diseases |
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Brazilian Society of Infectious Diseases |
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