Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents

Detalhes bibliográficos
Autor(a) principal: Glaner,Maria Fátima
Data de Publicação: 2014
Outros Autores: Nascimento,Thales Boaventura Rachid, Nóbrega,Otávio de Tôledo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Motriz (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742014000300332
Resumo: The purpose of this study was to analyze the association between APOE alleles and serum lipemia in adolescents with low and adequate aerobic fitness. The sample was comprised of 105 boys and 151 girls (49% and 46% from rural area) of European ancestry, aged 11 to 17 years, and classified according to: 1) APOE genotype: group ε2 (ε2/3+ε2/2), ε3 (ε3/3), and ε4 (ε3/4+ε4/4); 2) aerobic fitness: adequate or low; 3) serum lipemia: elevated total cholesterol (TC), low-density lipoprotein (LDL) and triglycerides, and low high-density lipoprotein (HDL). The results showed that aerobic fitness modulates the association between APOE alleles and serum lipemia in adolescents, suggesting that adequate aerobic fitness levels exert a greater effect of reducing TC and LDL in ε2 carriers, as well as of increasing HDL and reducing triglycerides in ε3 and ε4 carriers.
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spelling Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescentsapolipoproteins Ephysical enduranceadolescent healthlipoproteinsThe purpose of this study was to analyze the association between APOE alleles and serum lipemia in adolescents with low and adequate aerobic fitness. The sample was comprised of 105 boys and 151 girls (49% and 46% from rural area) of European ancestry, aged 11 to 17 years, and classified according to: 1) APOE genotype: group ε2 (ε2/3+ε2/2), ε3 (ε3/3), and ε4 (ε3/4+ε4/4); 2) aerobic fitness: adequate or low; 3) serum lipemia: elevated total cholesterol (TC), low-density lipoprotein (LDL) and triglycerides, and low high-density lipoprotein (HDL). The results showed that aerobic fitness modulates the association between APOE alleles and serum lipemia in adolescents, suggesting that adequate aerobic fitness levels exert a greater effect of reducing TC and LDL in ε2 carriers, as well as of increasing HDL and reducing triglycerides in ε3 and ε4 carriers.Universidade Estadual Paulista2014-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742014000300332Motriz: Revista de Educação Física v.20 n.3 2014reponame:Motriz (Online)instname:Universidade Estadual Paulista (UNESP)instacron:UNESP10.1590/S1980-65742014000300013info:eu-repo/semantics/openAccessGlaner,Maria FátimaNascimento,Thales Boaventura RachidNóbrega,Otávio de Tôledoeng2015-10-09T00:00:00Zoai:scielo:S1980-65742014000300332Revistahttp://www.periodicos.rc.biblioteca.unesp.br/index.php/motrizPUBhttps://old.scielo.br/oai/scielo-oai.phpmotriz@rc.unesp.br||mauerber@rc.unesp.br||azanesco@rc.unesp.br1980-65741415-9805opendoar:2022-11-08T16:30:19.951112Motriz (Online) - Universidade Estadual Paulista (UNESP)true
dc.title.none.fl_str_mv Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
title Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
spellingShingle Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
Glaner,Maria Fátima
apolipoproteins E
physical endurance
adolescent health
lipoproteins
title_short Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
title_full Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
title_fullStr Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
title_full_unstemmed Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
title_sort Aerobic fitness modulates the association between APOE genotypes and serum lipemia in adolescents
author Glaner,Maria Fátima
author_facet Glaner,Maria Fátima
Nascimento,Thales Boaventura Rachid
Nóbrega,Otávio de Tôledo
author_role author
author2 Nascimento,Thales Boaventura Rachid
Nóbrega,Otávio de Tôledo
author2_role author
author
dc.contributor.author.fl_str_mv Glaner,Maria Fátima
Nascimento,Thales Boaventura Rachid
Nóbrega,Otávio de Tôledo
dc.subject.por.fl_str_mv apolipoproteins E
physical endurance
adolescent health
lipoproteins
topic apolipoproteins E
physical endurance
adolescent health
lipoproteins
description The purpose of this study was to analyze the association between APOE alleles and serum lipemia in adolescents with low and adequate aerobic fitness. The sample was comprised of 105 boys and 151 girls (49% and 46% from rural area) of European ancestry, aged 11 to 17 years, and classified according to: 1) APOE genotype: group ε2 (ε2/3+ε2/2), ε3 (ε3/3), and ε4 (ε3/4+ε4/4); 2) aerobic fitness: adequate or low; 3) serum lipemia: elevated total cholesterol (TC), low-density lipoprotein (LDL) and triglycerides, and low high-density lipoprotein (HDL). The results showed that aerobic fitness modulates the association between APOE alleles and serum lipemia in adolescents, suggesting that adequate aerobic fitness levels exert a greater effect of reducing TC and LDL in ε2 carriers, as well as of increasing HDL and reducing triglycerides in ε3 and ε4 carriers.
publishDate 2014
dc.date.none.fl_str_mv 2014-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742014000300332
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1980-65742014000300332
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1980-65742014000300013
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Universidade Estadual Paulista
publisher.none.fl_str_mv Universidade Estadual Paulista
dc.source.none.fl_str_mv Motriz: Revista de Educação Física v.20 n.3 2014
reponame:Motriz (Online)
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Motriz (Online)
collection Motriz (Online)
repository.name.fl_str_mv Motriz (Online) - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv motriz@rc.unesp.br||mauerber@rc.unesp.br||azanesco@rc.unesp.br
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