Biological activity of microalgae in dermatophytes: Review

Detalhes bibliográficos
Autor(a) principal: Lage, Vivian Marina Gomes Barbosa
Data de Publicação: 2022
Outros Autores: Deegan, Kathleen Ramos, Santos, Gabriela Fontes, Barbosa, Cristiane de Jesus, Lima, Suzana Telles da Cunha
Tipo de documento: Artigo
Idioma: por
Título da fonte: Research, Society and Development
Texto Completo: https://rsdjournal.org/index.php/rsd/article/view/33404
Resumo: Microalgae are considered a rich source of biologically active metabolites with potential pharmacological use. In the pharmaceutical industry, microalgae extracts are found to present important biological activities, such as antifungal. Dermatophytosis are cutaneous mycoses caused by fungi called dermatophytes, microorganisms that have a special biotropism for keratinized tissues. The aim of this work was to conduct a literature review on the biological activity of microalgae extracts and compounds in dermatophyte fungi. This is a narrative review of the literature, carried out in the databases PubMed, LILACS, SciELO and Google Scholar. After search, eighteen articles published between 1960 and 2021, in English and French, were selected. Four groups of microalgae have already been explored for their antifungal activity: chlorophytes, diatoms, dinoflagellates and cyanobacteria, totaling 40 species of microalgae already tested in 19 species of dermatophytes. Diatoms and cyanobacteria have the largest number of tests performed against dermatophytes. The most tested species of dermatophytes are T. rubrum and T. menthagrophytes. The extracts of S. platensis, C. Braunii, T. nodosa and T. tenuis and the compounds isolated from the dinoflagellates Goniodoma sp., G. toxicus and Amphidinium sp. have the greatest inhibitory activity. The lack of standardization of tests and the antifungal activity of microalgae extracts already registered for dermatophytes encourages the carrying out of new studies to contemplate the great biodiversity and test the synergistic effect with commercial antifungals.
id UNIFEI_4faa782ab701e016a6b09f1908ee2545
oai_identifier_str oai:ojs.pkp.sfu.ca:article/33404
network_acronym_str UNIFEI
network_name_str Research, Society and Development
repository_id_str
spelling Biological activity of microalgae in dermatophytes: Review Actividad biológica de microalgas frente a dermatofitos: RevisiónAtividade biológica das microalgas em dermatófitos: RevisãoMicroalgasBioextratosDermatofitosesAtividade antifúngica.MicroalgaeBioextractsDermatophytosisAntifungal activity. MicroalgasBioextractosDermatofitosisActividad antifúngica.Microalgae are considered a rich source of biologically active metabolites with potential pharmacological use. In the pharmaceutical industry, microalgae extracts are found to present important biological activities, such as antifungal. Dermatophytosis are cutaneous mycoses caused by fungi called dermatophytes, microorganisms that have a special biotropism for keratinized tissues. The aim of this work was to conduct a literature review on the biological activity of microalgae extracts and compounds in dermatophyte fungi. This is a narrative review of the literature, carried out in the databases PubMed, LILACS, SciELO and Google Scholar. After search, eighteen articles published between 1960 and 2021, in English and French, were selected. Four groups of microalgae have already been explored for their antifungal activity: chlorophytes, diatoms, dinoflagellates and cyanobacteria, totaling 40 species of microalgae already tested in 19 species of dermatophytes. Diatoms and cyanobacteria have the largest number of tests performed against dermatophytes. The most tested species of dermatophytes are T. rubrum and T. menthagrophytes. The extracts of S. platensis, C. Braunii, T. nodosa and T. tenuis and the compounds isolated from the dinoflagellates Goniodoma sp., G. toxicus and Amphidinium sp. have the greatest inhibitory activity. The lack of standardization of tests and the antifungal activity of microalgae extracts already registered for dermatophytes encourages the carrying out of new studies to contemplate the great biodiversity and test the synergistic effect with commercial antifungals.Las microalgas se presentan como uma fuente valiosa de metabolitos biológicamente activos, con potencial uso farmacológico. En la industria farmacéutica, los extractos de microalgas se han destacado por sus importantes actividades biológicas, incluso la actividad antifúngica. Las dermatofitosis son micosis cutáneas causadas por hongos denominados dermatofitos, microorganismo que presenta biotropismo para los tejidos queratinizados. El objetivo de este trabajo consiste em generar una revisión bibliográfica respecto la actividad biológica de extractos y compuestos de microalgas frente a hongos dermatofitos. Consiste en una revisión narrativa de la literatura, en que se ha utilizado los portales web y bases de datos de PubMed, LILACS, SciELO y Google Scholar. Tras la búsqueda, se han seleccionado 18 artículos publicados entre los años 1960 y 2021, en inglés y francés. Se han evaluado cuatro grupos de microalgas respecto a su actividad antifúngica: clorofitas, diatomeas, dinoflagelados y cianobacterias, totalizando 40 especies de microalgas probadas contra 19 especies de dermatofitos. Las diatomeas y las cianobacterias tienen el mayor número de pruebas realizadas contra los dermatofitos. Las especies de dermatofitos más estudiadas han sido T. rubrum y T. menthagrophytes. Los extractos obtenidos de S. platensis, C. braunii, T. nodosa y T. tenuis han mostrado una mayor actividad inhibitoria em los hongos estudiados, además de compuestos aislados de las especies de dinoflagelados Goniodoma sp., G. toxicus y Amphidinium sp.. La falta de estandarización de las pruebas y el hecho de que ya se hayan identificado las actividades antifúngicas de las especies de microalgas para el control de los dermatofitos, anima a realizar más estudios centrados en la biodiversidad y el efecto sinérgico con los fármacos comerciales.As microalgas são consideradas uma rica fonte de metabólitos biologicamente ativos com potencial uso farmacológico. Na indústria farmacêutica, extratos microalgais se destacam por apresentarem importantes atividades biológicas, como a antifúngica. As dermatofitoses são micoses cutâneas ocasionadas por fungos denominados dermatófitos, microrganismos que possuem um biotropismo especial por tecidos queratinizados. O objetivo deste trabalho foi realizar uma revisão de literatura acerca da atividade biológica de extratos e compostos das microalgas em fungos dermatófitos. Trata-se de uma revisão narrativa da literatura, realizada nas bases de dados PubMed, LILACS, SciELO e Google Scholar. Após a busca, foram selecionados 18 artigos publicados entre os anos de 1960 e 2021, nos idiomas inglês e francês. Quatro grupos de microalgas já foram explorados quanto à atividade antifúngica: clorofíceas, diatomáceas, dinoflagelados e cianobactérias, totalizando 40 espécies de microalgas já testadas em 19 espécies de dermatófitos. As diatomáceas e cianobactérias possuem o maior número de testes realizados contra dermatófitos. As espécies de dermatófitos mais testadas foram o T. rubrum e o T. menthagrophytes. Os extratos de S. platensis, C. Braunii, T. nodosa e T. tenuis e os compostos isolados das espécies de dinoflagelados Goniodoma sp., G. toxicus e Amphidinium sp. apresentaram maior atividade inibitória. A falta de padronização dos testes e o potencial antifúngico das microalgas já registrado para os dermatófitos, encoraja a realização de novos estudos para contemplar a grande biodiversidade e testar o efeito sinérgico aditivo com drogas comerciais.Research, Society and Development2022-08-17info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/3340410.33448/rsd-v11i11.33404Research, Society and Development; Vol. 11 No. 11; e126111133404Research, Society and Development; Vol. 11 Núm. 11; e126111133404Research, Society and Development; v. 11 n. 11; e1261111334042525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/33404/28266Copyright (c) 2022 Vivian Marina Gomes Barbosa Lage; Kathleen Ramos Deegan; Gabriela Fontes Santos; Cristiane de Jesus Barbosa; Suzana Telles da Cunha Limahttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessLage, Vivian Marina Gomes BarbosaDeegan, Kathleen RamosSantos, Gabriela FontesBarbosa, Cristiane de JesusLima, Suzana Telles da Cunha2022-09-05T13:24:46Zoai:ojs.pkp.sfu.ca:article/33404Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:49:03.830643Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Biological activity of microalgae in dermatophytes: Review
Actividad biológica de microalgas frente a dermatofitos: Revisión
Atividade biológica das microalgas em dermatófitos: Revisão
title Biological activity of microalgae in dermatophytes: Review
spellingShingle Biological activity of microalgae in dermatophytes: Review
Lage, Vivian Marina Gomes Barbosa
Microalgas
Bioextratos
Dermatofitoses
Atividade antifúngica.
Microalgae
Bioextracts
Dermatophytosis
Antifungal activity.
Microalgas
Bioextractos
Dermatofitosis
Actividad antifúngica.
title_short Biological activity of microalgae in dermatophytes: Review
title_full Biological activity of microalgae in dermatophytes: Review
title_fullStr Biological activity of microalgae in dermatophytes: Review
title_full_unstemmed Biological activity of microalgae in dermatophytes: Review
title_sort Biological activity of microalgae in dermatophytes: Review
author Lage, Vivian Marina Gomes Barbosa
author_facet Lage, Vivian Marina Gomes Barbosa
Deegan, Kathleen Ramos
Santos, Gabriela Fontes
Barbosa, Cristiane de Jesus
Lima, Suzana Telles da Cunha
author_role author
author2 Deegan, Kathleen Ramos
Santos, Gabriela Fontes
Barbosa, Cristiane de Jesus
Lima, Suzana Telles da Cunha
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Lage, Vivian Marina Gomes Barbosa
Deegan, Kathleen Ramos
Santos, Gabriela Fontes
Barbosa, Cristiane de Jesus
Lima, Suzana Telles da Cunha
dc.subject.por.fl_str_mv Microalgas
Bioextratos
Dermatofitoses
Atividade antifúngica.
Microalgae
Bioextracts
Dermatophytosis
Antifungal activity.
Microalgas
Bioextractos
Dermatofitosis
Actividad antifúngica.
topic Microalgas
Bioextratos
Dermatofitoses
Atividade antifúngica.
Microalgae
Bioextracts
Dermatophytosis
Antifungal activity.
Microalgas
Bioextractos
Dermatofitosis
Actividad antifúngica.
description Microalgae are considered a rich source of biologically active metabolites with potential pharmacological use. In the pharmaceutical industry, microalgae extracts are found to present important biological activities, such as antifungal. Dermatophytosis are cutaneous mycoses caused by fungi called dermatophytes, microorganisms that have a special biotropism for keratinized tissues. The aim of this work was to conduct a literature review on the biological activity of microalgae extracts and compounds in dermatophyte fungi. This is a narrative review of the literature, carried out in the databases PubMed, LILACS, SciELO and Google Scholar. After search, eighteen articles published between 1960 and 2021, in English and French, were selected. Four groups of microalgae have already been explored for their antifungal activity: chlorophytes, diatoms, dinoflagellates and cyanobacteria, totaling 40 species of microalgae already tested in 19 species of dermatophytes. Diatoms and cyanobacteria have the largest number of tests performed against dermatophytes. The most tested species of dermatophytes are T. rubrum and T. menthagrophytes. The extracts of S. platensis, C. Braunii, T. nodosa and T. tenuis and the compounds isolated from the dinoflagellates Goniodoma sp., G. toxicus and Amphidinium sp. have the greatest inhibitory activity. The lack of standardization of tests and the antifungal activity of microalgae extracts already registered for dermatophytes encourages the carrying out of new studies to contemplate the great biodiversity and test the synergistic effect with commercial antifungals.
publishDate 2022
dc.date.none.fl_str_mv 2022-08-17
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33404
10.33448/rsd-v11i11.33404
url https://rsdjournal.org/index.php/rsd/article/view/33404
identifier_str_mv 10.33448/rsd-v11i11.33404
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/33404/28266
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 11 No. 11; e126111133404
Research, Society and Development; Vol. 11 Núm. 11; e126111133404
Research, Society and Development; v. 11 n. 11; e126111133404
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
_version_ 1797052770167029760

Registros relacionados