Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s12070-023-03609-4 http://hdl.handle.net/11449/248480 |
Resumo: | Necrotizing sialometaplasia (NS) is a rare, self-limiting, necrotizing inflammatory lesion, often involving the minor salivary glands of the palate. NS occurs often in men (60%) older than 45 years. Commonly, it presents as an ulcerative lesion, measuring 1 to 3 cm in diameter, with an evolution time of a few weeks or days, simulating malignancy. However, in some instances, the mucosal surface is intact, thus emphasizing the importance of considering NS in the differential diagnosis of oral ulcerative and non-ulcerative lesions. To date, 12 cases of non-ulcerated NS in the palate have been reported. Here, we report a 50-year-old male patient who presented a non-ulcerated, asymptomatic, nodular swelling 3 months ago, located on the hard palate, clinically suggesting salivary gland tumor or lymphoproliferative disorder. After biopsy, a diagnosis of non-ulcerated NS was established. After 4 weeks, the lesion evolved with complete resolution. After literature review, notably, unlike ulcerated NS, the non-ulcerated NS affected patients a decade younger (33 years vs. 45 years), with marked female predilection (83% vs. 40%) and not uncommon bilateral presentation (33% vs. 10%). NS should be considered in the differential diagnosis of ulcerative and non-ulcerative lesions affecting the palate. |
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Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature ReviewImmunohistochemistryNecrotizing sialometaplasiaOral mucosaPalateSalivary gland diseasesNecrotizing sialometaplasia (NS) is a rare, self-limiting, necrotizing inflammatory lesion, often involving the minor salivary glands of the palate. NS occurs often in men (60%) older than 45 years. Commonly, it presents as an ulcerative lesion, measuring 1 to 3 cm in diameter, with an evolution time of a few weeks or days, simulating malignancy. However, in some instances, the mucosal surface is intact, thus emphasizing the importance of considering NS in the differential diagnosis of oral ulcerative and non-ulcerative lesions. To date, 12 cases of non-ulcerated NS in the palate have been reported. Here, we report a 50-year-old male patient who presented a non-ulcerated, asymptomatic, nodular swelling 3 months ago, located on the hard palate, clinically suggesting salivary gland tumor or lymphoproliferative disorder. After biopsy, a diagnosis of non-ulcerated NS was established. After 4 weeks, the lesion evolved with complete resolution. After literature review, notably, unlike ulcerated NS, the non-ulcerated NS affected patients a decade younger (33 years vs. 45 years), with marked female predilection (83% vs. 40%) and not uncommon bilateral presentation (33% vs. 10%). NS should be considered in the differential diagnosis of ulcerative and non-ulcerative lesions affecting the palate.Oral Medicine Department of Diagnosis and Surgery Araraquara Dental School (UNESP)Oral Pathology Department of Stomatology Public Oral Health and Forensic Dentistry Ribeirão Preto Dental School (FORP/USP) University of São Paulo, Avenida do Caf?, S/N, SPDepartment of Pathology and Forensic Medicine FMRP/USP) Ribeirão Preto Medical School University of São Paulo, SPOral Medicine Department of Diagnosis and Surgery Araraquara Dental School (UNESP)Universidade Estadual Paulista (UNESP)Universidade de São Paulo (USP)Silva, Evânio Vilela [UNESP]Silveira, Heitor Albergoni [UNESP]Moreira, Thales Peres CandidoAugusto, JeffersonSilva, Paula Verona Ragusa [UNESP]Bufalino, Andreia [UNESP]León, Jorge Esquiche2023-07-29T13:45:13Z2023-07-29T13:45:13Z2023-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1007/s12070-023-03609-4Indian Journal of Otolaryngology and Head and Neck Surgery.0973-77072231-3796http://hdl.handle.net/11449/24848010.1007/s12070-023-03609-42-s2.0-85149627816Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengIndian Journal of Otolaryngology and Head and Neck Surgeryinfo:eu-repo/semantics/openAccess2023-07-29T13:45:13Zoai:repositorio.unesp.br:11449/248480Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T13:45:13Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
title |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
spellingShingle |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review Silva, Evânio Vilela [UNESP] Immunohistochemistry Necrotizing sialometaplasia Oral mucosa Palate Salivary gland diseases |
title_short |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
title_full |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
title_fullStr |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
title_full_unstemmed |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
title_sort |
Non-Ulcerated and Ulcerated Necrotizing Sialometaplasia: Report of an Additional Case and Literature Review |
author |
Silva, Evânio Vilela [UNESP] |
author_facet |
Silva, Evânio Vilela [UNESP] Silveira, Heitor Albergoni [UNESP] Moreira, Thales Peres Candido Augusto, Jefferson Silva, Paula Verona Ragusa [UNESP] Bufalino, Andreia [UNESP] León, Jorge Esquiche |
author_role |
author |
author2 |
Silveira, Heitor Albergoni [UNESP] Moreira, Thales Peres Candido Augusto, Jefferson Silva, Paula Verona Ragusa [UNESP] Bufalino, Andreia [UNESP] León, Jorge Esquiche |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Silva, Evânio Vilela [UNESP] Silveira, Heitor Albergoni [UNESP] Moreira, Thales Peres Candido Augusto, Jefferson Silva, Paula Verona Ragusa [UNESP] Bufalino, Andreia [UNESP] León, Jorge Esquiche |
dc.subject.por.fl_str_mv |
Immunohistochemistry Necrotizing sialometaplasia Oral mucosa Palate Salivary gland diseases |
topic |
Immunohistochemistry Necrotizing sialometaplasia Oral mucosa Palate Salivary gland diseases |
description |
Necrotizing sialometaplasia (NS) is a rare, self-limiting, necrotizing inflammatory lesion, often involving the minor salivary glands of the palate. NS occurs often in men (60%) older than 45 years. Commonly, it presents as an ulcerative lesion, measuring 1 to 3 cm in diameter, with an evolution time of a few weeks or days, simulating malignancy. However, in some instances, the mucosal surface is intact, thus emphasizing the importance of considering NS in the differential diagnosis of oral ulcerative and non-ulcerative lesions. To date, 12 cases of non-ulcerated NS in the palate have been reported. Here, we report a 50-year-old male patient who presented a non-ulcerated, asymptomatic, nodular swelling 3 months ago, located on the hard palate, clinically suggesting salivary gland tumor or lymphoproliferative disorder. After biopsy, a diagnosis of non-ulcerated NS was established. After 4 weeks, the lesion evolved with complete resolution. After literature review, notably, unlike ulcerated NS, the non-ulcerated NS affected patients a decade younger (33 years vs. 45 years), with marked female predilection (83% vs. 40%) and not uncommon bilateral presentation (33% vs. 10%). NS should be considered in the differential diagnosis of ulcerative and non-ulcerative lesions affecting the palate. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:45:13Z 2023-07-29T13:45:13Z 2023-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s12070-023-03609-4 Indian Journal of Otolaryngology and Head and Neck Surgery. 0973-7707 2231-3796 http://hdl.handle.net/11449/248480 10.1007/s12070-023-03609-4 2-s2.0-85149627816 |
url |
http://dx.doi.org/10.1007/s12070-023-03609-4 http://hdl.handle.net/11449/248480 |
identifier_str_mv |
Indian Journal of Otolaryngology and Head and Neck Surgery. 0973-7707 2231-3796 10.1007/s12070-023-03609-4 2-s2.0-85149627816 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Indian Journal of Otolaryngology and Head and Neck Surgery |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965513101606912 |