Necrotizing sialometaplasia as a cause of a non-ulcerated nodule in the hard palate: A case report

• Autor(a) principal: Oliveira Alves, Mônica [UNESP]
• Data de Publicação: 2011
• Outros Autores: Kitakawa, Dárcio [UNESP], Carvalho, Yasmin [UNESP], Guimarães Cabral, Luiz [UNESP], Almeida, Janete [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1186/1752-1947-5-406; http://hdl.handle.net/11449/72617
• topic: adult; biopsy; case report; female; hard palate; human; inflammatory infiltrate; lamina propria; mouth examination; mouth lesion; mouth ulcer; priority journal; salivary gland disease; temporomandibular joint disorder

Introduction. Necrotizing sialometaplasia is a benign, self-limiting and rare inflammatory disease which, on clinical and histological examination, mimics malignant neoplasms. Case report. We report the case of a healthy 25-year-old Caucasian woman with a three-week history of a painless lump on her hard palate. Oral examination revealed a nodule consisting of two lobules on the right side that measured 2.5 cm. Her mucosa was normal in color and a fluctuant area was detected in the posterior region upon palpation. Our patient was submitted to incisional biopsy and histopathological examination. The histological diagnosis was necrotizing sialometaplasia. The lesion had healed spontaneously after 30 days, with observed signs of involution of the nodule. Conclusion: Histopathological examination is necessary for the diagnosis of necrotizing sialometaplasia because the clinical features of this condition can mimic other diseases, particularly malignant neoplasms. © 2011 Oliveira Alves et al; licensee BioMed Central Ltd.