Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study
Autor(a) principal: | |
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Data de Publicação: | 2007 |
Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/art.22473 http://hdl.handle.net/11449/39410 |
Resumo: | Objective. To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA).Methods. In this multinational, multicenter, cross-sectional study, HRQOL of patients with JIA was assessed through the Child Health Questionnaire (CHQ) and was compared with that of healthy children of similar age from the same geographic area. of joint inflammation, Childhood Health Assessment Questionnaire (CHAQ), and erythrocyte sedimentation rate.Results. A total of 6,639 participants (3,324 with JIA and 3,315 healthy) were enrolled from 32 countries. The mean SD physical and psychosocial summary scores of the CHQ were significantly lower in patients with JIA than in healthy children (physical: 44.5 +/- 10.6 versus 54.6 +/- 4.0, P < 0.0001; psychosocial: 47.6 +/- 8.7 versus 51.9 +/- 7.59 P < 0.0001), with the physical well-being domain being most impaired. Patients with persistent oligoarthritis had better HRQOL compared with other subtypes, whereas HRQOL was similar across patients with systemic arthritis, polyarthritis, and extended oligoarthritis. A CHAQ score > 1 and a pain intensity rating > 3.4 cm on a 10-cm visual analog scale were the strongest determinants of poorer HRQOL in the physical and psychosocial domains, respectively.Conclusion. We found that patients with JIA have a significant impairment of their HRQOL compared with healthy peers, particularly in the physical domain. Physical well-being was mostly affected by the level of functional impairment, whereas the intensity of pain had the greatest influence on psychosocial health. |
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Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort studyhealth-related quality of lifejuvenile idiopathic arthritisdisabilityObjective. To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA).Methods. In this multinational, multicenter, cross-sectional study, HRQOL of patients with JIA was assessed through the Child Health Questionnaire (CHQ) and was compared with that of healthy children of similar age from the same geographic area. of joint inflammation, Childhood Health Assessment Questionnaire (CHAQ), and erythrocyte sedimentation rate.Results. A total of 6,639 participants (3,324 with JIA and 3,315 healthy) were enrolled from 32 countries. The mean SD physical and psychosocial summary scores of the CHQ were significantly lower in patients with JIA than in healthy children (physical: 44.5 +/- 10.6 versus 54.6 +/- 4.0, P < 0.0001; psychosocial: 47.6 +/- 8.7 versus 51.9 +/- 7.59 P < 0.0001), with the physical well-being domain being most impaired. Patients with persistent oligoarthritis had better HRQOL compared with other subtypes, whereas HRQOL was similar across patients with systemic arthritis, polyarthritis, and extended oligoarthritis. A CHAQ score > 1 and a pain intensity rating > 3.4 cm on a 10-cm visual analog scale were the strongest determinants of poorer HRQOL in the physical and psychosocial domains, respectively.Conclusion. We found that patients with JIA have a significant impairment of their HRQOL compared with healthy peers, particularly in the physical domain. Physical well-being was mostly affected by the level of functional impairment, whereas the intensity of pain had the greatest influence on psychosocial health.Univ Genoa, Pediat Rheumatol Int Trials Org, IRCCS G Gaslini, I-16147 Genoa, ItalyIRCCS G Gaslini, Serv Epidemiol & Biostat, Genoa, ItalyHop Necker Enfants Malad, Paris, FranceUniv Estadual Paulista, Botucatu, SP, BrazilPrincess Margaret Hosp Children, Perth, WA, AustraliaHanyang Univ, Med Ctr, Hosp Rheumat Dis, Seoul 133791, South KoreaUniv Ziekenhuis Gent, Ctr Kinderreumatol, Ghent, BelgiumAllgemeines Krankenhaus Eilbeck, Hamburg, GermanyInst Nacl Rehabil, Mexico City, DF, MexicoWilhelmina Childrens Hosp, Utrecht, NetherlandsUniv Helsinki, Cent Hosp, Hosp Children & Adolescents, Helsinki, FinlandFac Med 1, Prague, Czech RepublicGen Fac Hosp, Prague, Czech RepublicInst Madrileno Salud, Madrid, SpainAristotle Univ Thessaloniki, Ippokration Gen Hosp, Thessaloniki, GreeceHop Univ Geneva, Geneva, SwitzerlandRAMS, Inst Rheumatol, Moscow, RussiaCerrahpasa Tip Fak, Istanbul, TurkeyCleveland Clin Fdn, Cleveland, OH 44195 USAHealthActCHQ, Boston, MA USAUniv Genoa, IRCCS G Gaslini, Genoa, ItalyUniv Estadual Paulista, Botucatu, SP, BrazilWiley-BlackwellUniv GenoaIRCCS G GasliniHop Necker Enfants MaladUniversidade Estadual Paulista (Unesp)Princess Margaret Hosp ChildrenHanyang UnivUniv Ziekenhuis GentAllgemeines Krankenhaus EilbeckInst Nacl RehabilWilhelmina Childrens HospUniv HelsinkiFac Med 1Gen Fac HospInst Madrileno SaludAristotle Univ ThessalonikiHop Univ GenevaRAMSCerrahpasa Tip FakCleveland Clin FdnHealthActCHQOliveira, SheilaRavelli, AngeloPistorio, AngelaCastell, EstebanMalattia, ClaraPrieur, Anne MarieSaad-Magalhaes, ClaudiaMurray, Kevin J.Bae, Sang-CheolJoos, RikFoeldvari, IvanDuarte-Salazar, CarolinaWulffraat, NicoLahdenne, PekkaDolezalova, Pavlade Inocencio, JaimeKanakoudi-Tsakalidou, FlorenceHofer, MichaelNikishina, IrinaOzdogan, HuriHashkes, Philip J.Landgraf, Jeanne M.Martini, AlbertoRuperto, Nicolino2014-05-20T15:29:57Z2014-05-20T15:29:57Z2007-02-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article35-43application/pdfhttp://dx.doi.org/10.1002/art.22473Arthritis & Rheumatism-arthritis Care & Research. Hoboken: Wiley-liss, v. 57, n. 1, p. 35-43, 2007.0004-3591http://hdl.handle.net/11449/3941010.1002/art.22473WOS:000244138100006WOS000244138100006.pdf70983100083716320000-0002-7631-7093Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengArthritis & Rheumatism-arthritis Care & Researchinfo:eu-repo/semantics/openAccess2023-10-02T06:00:48Zoai:repositorio.unesp.br:11449/39410Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-02T06:00:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
title |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
spellingShingle |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study Oliveira, Sheila health-related quality of life juvenile idiopathic arthritis disability |
title_short |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
title_full |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
title_fullStr |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
title_full_unstemmed |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
title_sort |
Proxy-reported health-related quality of life of patients with juvenile idiopathic arthritis: Pediatric rheumatology international trials organization multinational quality of life cohort study |
author |
Oliveira, Sheila |
author_facet |
Oliveira, Sheila Ravelli, Angelo Pistorio, Angela Castell, Esteban Malattia, Clara Prieur, Anne Marie Saad-Magalhaes, Claudia Murray, Kevin J. Bae, Sang-Cheol Joos, Rik Foeldvari, Ivan Duarte-Salazar, Carolina Wulffraat, Nico Lahdenne, Pekka Dolezalova, Pavla de Inocencio, Jaime Kanakoudi-Tsakalidou, Florence Hofer, Michael Nikishina, Irina Ozdogan, Huri Hashkes, Philip J. Landgraf, Jeanne M. Martini, Alberto Ruperto, Nicolino |
author_role |
author |
author2 |
Ravelli, Angelo Pistorio, Angela Castell, Esteban Malattia, Clara Prieur, Anne Marie Saad-Magalhaes, Claudia Murray, Kevin J. Bae, Sang-Cheol Joos, Rik Foeldvari, Ivan Duarte-Salazar, Carolina Wulffraat, Nico Lahdenne, Pekka Dolezalova, Pavla de Inocencio, Jaime Kanakoudi-Tsakalidou, Florence Hofer, Michael Nikishina, Irina Ozdogan, Huri Hashkes, Philip J. Landgraf, Jeanne M. Martini, Alberto Ruperto, Nicolino |
author2_role |
author author author author author author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Univ Genoa IRCCS G Gaslini Hop Necker Enfants Malad Universidade Estadual Paulista (Unesp) Princess Margaret Hosp Children Hanyang Univ Univ Ziekenhuis Gent Allgemeines Krankenhaus Eilbeck Inst Nacl Rehabil Wilhelmina Childrens Hosp Univ Helsinki Fac Med 1 Gen Fac Hosp Inst Madrileno Salud Aristotle Univ Thessaloniki Hop Univ Geneva RAMS Cerrahpasa Tip Fak Cleveland Clin Fdn HealthActCHQ |
dc.contributor.author.fl_str_mv |
Oliveira, Sheila Ravelli, Angelo Pistorio, Angela Castell, Esteban Malattia, Clara Prieur, Anne Marie Saad-Magalhaes, Claudia Murray, Kevin J. Bae, Sang-Cheol Joos, Rik Foeldvari, Ivan Duarte-Salazar, Carolina Wulffraat, Nico Lahdenne, Pekka Dolezalova, Pavla de Inocencio, Jaime Kanakoudi-Tsakalidou, Florence Hofer, Michael Nikishina, Irina Ozdogan, Huri Hashkes, Philip J. Landgraf, Jeanne M. Martini, Alberto Ruperto, Nicolino |
dc.subject.por.fl_str_mv |
health-related quality of life juvenile idiopathic arthritis disability |
topic |
health-related quality of life juvenile idiopathic arthritis disability |
description |
Objective. To investigate the proxy-reported health-related quality of life (HRQOL) and its determinants in patients with juvenile idiopathic arthritis (JIA).Methods. In this multinational, multicenter, cross-sectional study, HRQOL of patients with JIA was assessed through the Child Health Questionnaire (CHQ) and was compared with that of healthy children of similar age from the same geographic area. of joint inflammation, Childhood Health Assessment Questionnaire (CHAQ), and erythrocyte sedimentation rate.Results. A total of 6,639 participants (3,324 with JIA and 3,315 healthy) were enrolled from 32 countries. The mean SD physical and psychosocial summary scores of the CHQ were significantly lower in patients with JIA than in healthy children (physical: 44.5 +/- 10.6 versus 54.6 +/- 4.0, P < 0.0001; psychosocial: 47.6 +/- 8.7 versus 51.9 +/- 7.59 P < 0.0001), with the physical well-being domain being most impaired. Patients with persistent oligoarthritis had better HRQOL compared with other subtypes, whereas HRQOL was similar across patients with systemic arthritis, polyarthritis, and extended oligoarthritis. A CHAQ score > 1 and a pain intensity rating > 3.4 cm on a 10-cm visual analog scale were the strongest determinants of poorer HRQOL in the physical and psychosocial domains, respectively.Conclusion. We found that patients with JIA have a significant impairment of their HRQOL compared with healthy peers, particularly in the physical domain. Physical well-being was mostly affected by the level of functional impairment, whereas the intensity of pain had the greatest influence on psychosocial health. |
publishDate |
2007 |
dc.date.none.fl_str_mv |
2007-02-15 2014-05-20T15:29:57Z 2014-05-20T15:29:57Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/art.22473 Arthritis & Rheumatism-arthritis Care & Research. Hoboken: Wiley-liss, v. 57, n. 1, p. 35-43, 2007. 0004-3591 http://hdl.handle.net/11449/39410 10.1002/art.22473 WOS:000244138100006 WOS000244138100006.pdf 7098310008371632 0000-0002-7631-7093 |
url |
http://dx.doi.org/10.1002/art.22473 http://hdl.handle.net/11449/39410 |
identifier_str_mv |
Arthritis & Rheumatism-arthritis Care & Research. Hoboken: Wiley-liss, v. 57, n. 1, p. 35-43, 2007. 0004-3591 10.1002/art.22473 WOS:000244138100006 WOS000244138100006.pdf 7098310008371632 0000-0002-7631-7093 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Arthritis & Rheumatism-arthritis Care & Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
35-43 application/pdf |
dc.publisher.none.fl_str_mv |
Wiley-Blackwell |
publisher.none.fl_str_mv |
Wiley-Blackwell |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1792961435544846336 |