Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3168/jds.2020-19275 http://hdl.handle.net/11449/210138 |
Resumo: | Staphylococcus aureus can elicit mild to more severe degrees of mastitis in cattle, depending on the response of the host's immune system and the virulence factors of the specific isolate. Several virulence factors are controlled by a global regulatory system, designated accessory gene regulator (agr). Thus, the objective was to examine associations between different capsular and agr types and the severity of bovine mastitis caused by S. aureus. All isolates were obtained from bovine subclinical (n = 50), mild clinical (n = 73), and moderate clinical mastitis cases (n = 28). Isolates containing the agrI gene and lacking the agr locus (agr(-)) were more prevalent among subclinical than clinical mastitis cases, whereas isolates containing the agrII and agrIII genes were more prevalent among clinical mastitis cases. The capsular types 5 (cap5) and 8 (cap8) were found in 42 and 44%, respectively, of the isolates obtained from subclinical cases and in 38.6 and 58.4%, respectively, of those isolated from clinical mastitis cases. Capsular type was not associated with type of mastitis (subclinical, mild clinical, or moderate clinical). We found a strong association between agr type and type of mastitis, suggesting that knowledge of S. aureus genetic profiles could be an additional tool to control this disease. |
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Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureuscapsuleimmune systemStaphylococcus aureusaccessory gene regulator (agr)Staphylococcus aureus can elicit mild to more severe degrees of mastitis in cattle, depending on the response of the host's immune system and the virulence factors of the specific isolate. Several virulence factors are controlled by a global regulatory system, designated accessory gene regulator (agr). Thus, the objective was to examine associations between different capsular and agr types and the severity of bovine mastitis caused by S. aureus. All isolates were obtained from bovine subclinical (n = 50), mild clinical (n = 73), and moderate clinical mastitis cases (n = 28). Isolates containing the agrI gene and lacking the agr locus (agr(-)) were more prevalent among subclinical than clinical mastitis cases, whereas isolates containing the agrII and agrIII genes were more prevalent among clinical mastitis cases. The capsular types 5 (cap5) and 8 (cap8) were found in 42 and 44%, respectively, of the isolates obtained from subclinical cases and in 38.6 and 58.4%, respectively, of those isolated from clinical mastitis cases. Capsular type was not associated with type of mastitis (subclinical, mild clinical, or moderate clinical). We found a strong association between agr type and type of mastitis, suggesting that knowledge of S. aureus genetic profiles could be an additional tool to control this disease.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Sao Paulo State Univ, Inst Biosci, Dept Chem & Biol Sci, Rua Dr Plinio Pinto e Silva, BR-18618691 Botucatu, SP, BrazilSao Paulo State Univ, Dept Anim Prod & Prevent Vet Med, Rua Prof Dr Walter Mauricio Correa, BR-18618681 Botucatu, SP, BrazilUniv Sao Paulo, Sch Vet Med & Anim Sci, Dept Anim Nutr & Prod, Ave Duque Caxias Norte 225, BR-13635900 Pirassununga, SP, BrazilSao Paulo State Univ, Inst Biosci, Dept Chem & Biol Sci, Rua Dr Plinio Pinto e Silva, BR-18618691 Botucatu, SP, BrazilSao Paulo State Univ, Dept Anim Prod & Prevent Vet Med, Rua Prof Dr Walter Mauricio Correa, BR-18618681 Botucatu, SP, BrazilCAPES: 001CNPq: 302383/2018-2Elsevier B.V.Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)Rossi, Bruna F. [UNESP]Bonsaglia, Erika C. R. [UNESP]Pantoja, Jose C. F. [UNESP]Santos, MarcosGoncalves, Juliano L.Fernandes Junior, Ary [UNESP]Rall, Vera L. M. [UNESP]2021-06-25T12:40:48Z2021-06-25T12:40:48Z2021-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article3564-3568http://dx.doi.org/10.3168/jds.2020-19275Journal Of Dairy Science. New York: Elsevier Science Inc, v. 104, n. 3, p. 3564-3568, 2021.0022-0302http://hdl.handle.net/11449/21013810.3168/jds.2020-19275WOS:000630004500087Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal Of Dairy Scienceinfo:eu-repo/semantics/openAccess2021-10-23T20:11:16Zoai:repositorio.unesp.br:11449/210138Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T20:11:16Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
title |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
spellingShingle |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus Rossi, Bruna F. [UNESP] capsule immune system Staphylococcus aureus accessory gene regulator (agr) |
title_short |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
title_full |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
title_fullStr |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
title_full_unstemmed |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
title_sort |
Short communication: Association between the accessory gene regulator (agr) group and the severity of bovine mastitis caused by Staphylococcus aureus |
author |
Rossi, Bruna F. [UNESP] |
author_facet |
Rossi, Bruna F. [UNESP] Bonsaglia, Erika C. R. [UNESP] Pantoja, Jose C. F. [UNESP] Santos, Marcos Goncalves, Juliano L. Fernandes Junior, Ary [UNESP] Rall, Vera L. M. [UNESP] |
author_role |
author |
author2 |
Bonsaglia, Erika C. R. [UNESP] Pantoja, Jose C. F. [UNESP] Santos, Marcos Goncalves, Juliano L. Fernandes Junior, Ary [UNESP] Rall, Vera L. M. [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) |
dc.contributor.author.fl_str_mv |
Rossi, Bruna F. [UNESP] Bonsaglia, Erika C. R. [UNESP] Pantoja, Jose C. F. [UNESP] Santos, Marcos Goncalves, Juliano L. Fernandes Junior, Ary [UNESP] Rall, Vera L. M. [UNESP] |
dc.subject.por.fl_str_mv |
capsule immune system Staphylococcus aureus accessory gene regulator (agr) |
topic |
capsule immune system Staphylococcus aureus accessory gene regulator (agr) |
description |
Staphylococcus aureus can elicit mild to more severe degrees of mastitis in cattle, depending on the response of the host's immune system and the virulence factors of the specific isolate. Several virulence factors are controlled by a global regulatory system, designated accessory gene regulator (agr). Thus, the objective was to examine associations between different capsular and agr types and the severity of bovine mastitis caused by S. aureus. All isolates were obtained from bovine subclinical (n = 50), mild clinical (n = 73), and moderate clinical mastitis cases (n = 28). Isolates containing the agrI gene and lacking the agr locus (agr(-)) were more prevalent among subclinical than clinical mastitis cases, whereas isolates containing the agrII and agrIII genes were more prevalent among clinical mastitis cases. The capsular types 5 (cap5) and 8 (cap8) were found in 42 and 44%, respectively, of the isolates obtained from subclinical cases and in 38.6 and 58.4%, respectively, of those isolated from clinical mastitis cases. Capsular type was not associated with type of mastitis (subclinical, mild clinical, or moderate clinical). We found a strong association between agr type and type of mastitis, suggesting that knowledge of S. aureus genetic profiles could be an additional tool to control this disease. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T12:40:48Z 2021-06-25T12:40:48Z 2021-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3168/jds.2020-19275 Journal Of Dairy Science. New York: Elsevier Science Inc, v. 104, n. 3, p. 3564-3568, 2021. 0022-0302 http://hdl.handle.net/11449/210138 10.3168/jds.2020-19275 WOS:000630004500087 |
url |
http://dx.doi.org/10.3168/jds.2020-19275 http://hdl.handle.net/11449/210138 |
identifier_str_mv |
Journal Of Dairy Science. New York: Elsevier Science Inc, v. 104, n. 3, p. 3564-3568, 2021. 0022-0302 10.3168/jds.2020-19275 WOS:000630004500087 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal Of Dairy Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
3564-3568 |
dc.publisher.none.fl_str_mv |
Elsevier B.V. |
publisher.none.fl_str_mv |
Elsevier B.V. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964907960008704 |