Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/s12889-023-15545-7 http://hdl.handle.net/11449/248642 |
Resumo: | Background: This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods: A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results: Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p < 0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β = 0.005; R2 = 0.35; p = 0.040) and upper limbs aBMD (β = 0.005; R2 = 0.55; p = 0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β = 0.003; R2 = 0.06; p = 0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE) = 0.0025; 95%CI = 0.0005–0.0048), and upper limbs aBMD (IE = 0.0040; 95%CI = 0.0017–0.0069). Conclusions: Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthood handgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood. |
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Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthoodBone healthGrowthMuscle strengthPhysical fitnessBackground: This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods: A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results: Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p < 0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β = 0.005; R2 = 0.35; p = 0.040) and upper limbs aBMD (β = 0.005; R2 = 0.55; p = 0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β = 0.003; R2 = 0.06; p = 0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE) = 0.0025; 95%CI = 0.0005–0.0048), and upper limbs aBMD (IE = 0.0040; 95%CI = 0.0017–0.0069). Conclusions: Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthood handgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood.Laboratory of Physical Activity and Health Center of Physical Education and Sports Londrina State University - UEL, Highway Celso Garcia Cid, Km 380, University Campus, Paraná, P.O. box 6001Department of Humanities Federal Technological University of Paraná - UTFPR, ParanáFederal University of Mato Grosso do Sul – UFMS Mato Grosso do SulDepartment of Physical Education Exercise Research Laboratory (LIVE) Faculdade de Ciências e Tecnologia State São Paulo University – UNESP, Presidente PrudenteFaculty of Sports Sciences and Physical Education University of CoimbraUniversity of AlgarveDepartment of Physical Education Exercise Research Laboratory (LIVE) Faculdade de Ciências e Tecnologia State São Paulo University – UNESP, Presidente PrudenteUniversidade Estadual de Londrina (UEL)Federal Technological University of Paraná - UTFPRUniversidade Federal de Mato Grosso do Sul (UFMS)Universidade Estadual Paulista (UNESP)University of CoimbraUniversity of AlgarveBarbosa, Cynthia Correa Lopesda Costa, Julio CesarRomanzini, Catiana Leila PossamaiBatista, Mariana BiagiBlasquez-Shigaki, GabrielaFernandes, Rômulo Araújo [UNESP]Martinho, Diogo V.Oliveira, TomásRibeiro, Luís P.Coelho-e-Silva, Manuel JoãoRonque, Enio Ricardo Vaz2023-07-29T13:49:37Z2023-07-29T13:49:37Z2023-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1186/s12889-023-15545-7BMC Public Health, v. 23, n. 1, 2023.1471-2458http://hdl.handle.net/11449/24864210.1186/s12889-023-15545-72-s2.0-85151785035Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBMC Public Healthinfo:eu-repo/semantics/openAccess2023-07-29T13:49:37Zoai:repositorio.unesp.br:11449/248642Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T13:49:37Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
spellingShingle |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood Barbosa, Cynthia Correa Lopes Bone health Growth Muscle strength Physical fitness |
title_short |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_full |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_fullStr |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_full_unstemmed |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
title_sort |
Interrelationship between muscle fitness in childhood and bone mineral density in adulthood: mediation analysis of muscle fitness in adulthood |
author |
Barbosa, Cynthia Correa Lopes |
author_facet |
Barbosa, Cynthia Correa Lopes da Costa, Julio Cesar Romanzini, Catiana Leila Possamai Batista, Mariana Biagi Blasquez-Shigaki, Gabriela Fernandes, Rômulo Araújo [UNESP] Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís P. Coelho-e-Silva, Manuel João Ronque, Enio Ricardo Vaz |
author_role |
author |
author2 |
da Costa, Julio Cesar Romanzini, Catiana Leila Possamai Batista, Mariana Biagi Blasquez-Shigaki, Gabriela Fernandes, Rômulo Araújo [UNESP] Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís P. Coelho-e-Silva, Manuel João Ronque, Enio Ricardo Vaz |
author2_role |
author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual de Londrina (UEL) Federal Technological University of Paraná - UTFPR Universidade Federal de Mato Grosso do Sul (UFMS) Universidade Estadual Paulista (UNESP) University of Coimbra University of Algarve |
dc.contributor.author.fl_str_mv |
Barbosa, Cynthia Correa Lopes da Costa, Julio Cesar Romanzini, Catiana Leila Possamai Batista, Mariana Biagi Blasquez-Shigaki, Gabriela Fernandes, Rômulo Araújo [UNESP] Martinho, Diogo V. Oliveira, Tomás Ribeiro, Luís P. Coelho-e-Silva, Manuel João Ronque, Enio Ricardo Vaz |
dc.subject.por.fl_str_mv |
Bone health Growth Muscle strength Physical fitness |
topic |
Bone health Growth Muscle strength Physical fitness |
description |
Background: This study was aimed to examine the relationship between muscular fitness indicators in childhood and areal bone mineral density (aBMD) in adulthood and to verify whether the relationship is mediated by performance on muscular fitness indicators in adulthood. Methods: A sample of 138 healthy adults (69 males; 22.3 years) were followed after a previous assessment at the age of 7–10 years. Stature, body mass and muscular fitness indicators (handgrip strength, standing long jump and sit-ups tests) were assessed in childhood and adulthood. Additionally, total body, upper limbs, lower limbs, right femoral neck and lumbar spine aBMD was assessed in adulthood using dual X-ray absorptiometry. Analysis included descriptive statistics; t-test or Mann-Whitney U-test for comparison between males and females, multiple linear regression for the prediction aBMD from muscular fitness indicators in childhood, mediation analysis of the respective muscular fitness indicators in adulthood and the relationship between muscular fitness indicators in childhood and aBMD. Results: Males were stronger compared to females regarding muscular fitness indicators in childhood and adulthood, and presented higher mean values for aBMD in adulthood, except for lumbar spine (p < 0.05). Regression analysis revealed that some muscular fitness indicators in childhood showed significant positive relationship with bone health indicators in adulthood, such as: handgrip strength and total body aBMD (β = 0.005; R2 = 0.35; p = 0.040) and upper limbs aBMD (β = 0.005; R2 = 0.55; p = 0.019); and sit-ups test was a significant predictors of lumbar spine BMD (β = 0.003; R2 = 0.06; p = 0.039). Mediation analysis pointed out the following: adulthood handgrip strength mediated relationships between childhood handgrip strength and total aBMD (indirect effect (IE) = 0.0025; 95%CI = 0.0005–0.0048), and upper limbs aBMD (IE = 0.0040; 95%CI = 0.0017–0.0069). Conclusions: Muscular fitness indicators in childhood showed significant relationship with bone health indicators in adulthood and the sit-ups test in childhood had direct effect on lumbar spine aBMD in adulthood. Adulthood handgrip strength mediated the relationship between childhood handgrip strength and total body and upper limb aBMD, pointing out that muscular fitness in childhood may be a aBMD determinant in adulthood, especially when higher muscle fitness performance is maintained in adulthood. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:49:37Z 2023-07-29T13:49:37Z 2023-12-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/s12889-023-15545-7 BMC Public Health, v. 23, n. 1, 2023. 1471-2458 http://hdl.handle.net/11449/248642 10.1186/s12889-023-15545-7 2-s2.0-85151785035 |
url |
http://dx.doi.org/10.1186/s12889-023-15545-7 http://hdl.handle.net/11449/248642 |
identifier_str_mv |
BMC Public Health, v. 23, n. 1, 2023. 1471-2458 10.1186/s12889-023-15545-7 2-s2.0-85151785035 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
BMC Public Health |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965694015569920 |