Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1980-657420220012321 http://hdl.handle.net/11449/233952 |
Resumo: | Aim: This study evaluated the effects of 10 weeks of combined exercise training on the salivary oxidative profile of hypertensive and normotensive postmenopausal women. Methods: Twenty-six non-obese postmenopausal women were divided into two groups: the hypertensive group (HT; n = 13; 58.9 ± 3.9 years; and BMI of 27.7 ± 4.6 kg/m2) or the normotensive group (NT; n = 13; 52.7 ± 5.2 years; and BMI of 26.9 ± 2.9 kg/m2). They performed 30 sessions of combined exercises over 10 weeks: 45 min per session, three times a week. Resting saliva samples were collected after an overnight fast to evaluate salivary nitrite levels and oxidative stress markers before and after training. Results: Two-way ANOVA showed that there was no difference in the responses over time between the hypertensive and normotensive groups in catalase, superoxide dismutase salivary activity, total antioxidant capacity, or lipid peroxidation. However, superoxide dismutase activity (ΔHT -0.87 ± 14.53 SOD/mg protein; ΔNT: 7.13 ± 9.39 SOD/mg protein; p < 0.01) and nitrite levels (ΔHT 10.32 ± 60.83 mM; ΔNT 101.92 ± 149.57 mM; p = 0.03) were higher overall in the hypertensive group compared to the normotensive group. Moreover, salivary nitrite levels increased over time (p = 0.04) in both groups. Conclusion: 10 weeks of combined exercise training did not change salivary oxidative stress markers in either normotensive or hypertensive postmenopausal women, although, after exercise training, nitrite levels increased in both groups, even with higher baseline salivary nitrite levels in hypertensive women. Thus, recurrent exercise seems to be a safe strategy after menopause from the standpoint of oxidative stress, regardless of the presence of hypertension. |
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Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal womenClimactericCombined exerciseNitriteSalivaSuperoxide dismutaseAim: This study evaluated the effects of 10 weeks of combined exercise training on the salivary oxidative profile of hypertensive and normotensive postmenopausal women. Methods: Twenty-six non-obese postmenopausal women were divided into two groups: the hypertensive group (HT; n = 13; 58.9 ± 3.9 years; and BMI of 27.7 ± 4.6 kg/m2) or the normotensive group (NT; n = 13; 52.7 ± 5.2 years; and BMI of 26.9 ± 2.9 kg/m2). They performed 30 sessions of combined exercises over 10 weeks: 45 min per session, three times a week. Resting saliva samples were collected after an overnight fast to evaluate salivary nitrite levels and oxidative stress markers before and after training. Results: Two-way ANOVA showed that there was no difference in the responses over time between the hypertensive and normotensive groups in catalase, superoxide dismutase salivary activity, total antioxidant capacity, or lipid peroxidation. However, superoxide dismutase activity (ΔHT -0.87 ± 14.53 SOD/mg protein; ΔNT: 7.13 ± 9.39 SOD/mg protein; p < 0.01) and nitrite levels (ΔHT 10.32 ± 60.83 mM; ΔNT 101.92 ± 149.57 mM; p = 0.03) were higher overall in the hypertensive group compared to the normotensive group. Moreover, salivary nitrite levels increased over time (p = 0.04) in both groups. Conclusion: 10 weeks of combined exercise training did not change salivary oxidative stress markers in either normotensive or hypertensive postmenopausal women, although, after exercise training, nitrite levels increased in both groups, even with higher baseline salivary nitrite levels in hypertensive women. Thus, recurrent exercise seems to be a safe strategy after menopause from the standpoint of oxidative stress, regardless of the presence of hypertension.Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG)Universidade Federal de Uberlândia Laboratório de Fisiologia Cardiorrespiratória e Metabólica, Uberlândia, MGUniversidade Federal de Uberlândia Instituto de Biotecnologia Laboratório de Bioquímica e Biologia Molecular, Uberlândia, MGUniversidade Metropolitana de Santos Faculdade de Medicina, Santos, SPUniversidade Estadual Paulista “Júlio de Mesquita Filho” Departamento de Educação Física Instituto de Biociências, SPUniversidade Estadual Paulista “Júlio de Mesquita Filho” Departamento de Educação Física Instituto de Biociências, SPFAPEMIG: APQ-00750-14Universidade Federal de Uberlândia (UFU)Faculdade de MedicinaUniversidade Estadual Paulista (UNESP)Amaral, Ana LuizaMariano, Igor MoraesGiolo, Jéssica SanjuliãoDechichi, Juliene Gonçalves Costade Souza, Adriele VieiraBatista, Jaqueline Pontesde Souza, Tállita Cristina FerreiraCaixeta, Douglas CarvalhoPeixoto, Leonardo GomesTeixeira, Renata RolandEspindola, Foued SalmenPuga, Guilherme MoraisZanesco, Angelina [UNESP]2022-05-01T11:54:09Z2022-05-01T11:54:09Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1590/S1980-657420220012321Motriz. Revista de Educacao Fisica, v. 28.1980-65741415-9805http://hdl.handle.net/11449/23395210.1590/S1980-6574202200123212-s2.0-85121985051Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengMotriz. Revista de Educacao Fisicainfo:eu-repo/semantics/openAccess2022-05-01T11:54:09Zoai:repositorio.unesp.br:11449/233952Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-05-01T11:54:09Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
title |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
spellingShingle |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women Amaral, Ana Luiza Climacteric Combined exercise Nitrite Saliva Superoxide dismutase |
title_short |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
title_full |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
title_fullStr |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
title_full_unstemmed |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
title_sort |
Effects of combined exercise on salivary oxidative stress in hypertensive and normotensive postmenopausal women |
author |
Amaral, Ana Luiza |
author_facet |
Amaral, Ana Luiza Mariano, Igor Moraes Giolo, Jéssica Sanjulião Dechichi, Juliene Gonçalves Costa de Souza, Adriele Vieira Batista, Jaqueline Pontes de Souza, Tállita Cristina Ferreira Caixeta, Douglas Carvalho Peixoto, Leonardo Gomes Teixeira, Renata Roland Espindola, Foued Salmen Puga, Guilherme Morais Zanesco, Angelina [UNESP] |
author_role |
author |
author2 |
Mariano, Igor Moraes Giolo, Jéssica Sanjulião Dechichi, Juliene Gonçalves Costa de Souza, Adriele Vieira Batista, Jaqueline Pontes de Souza, Tállita Cristina Ferreira Caixeta, Douglas Carvalho Peixoto, Leonardo Gomes Teixeira, Renata Roland Espindola, Foued Salmen Puga, Guilherme Morais Zanesco, Angelina [UNESP] |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal de Uberlândia (UFU) Faculdade de Medicina Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Amaral, Ana Luiza Mariano, Igor Moraes Giolo, Jéssica Sanjulião Dechichi, Juliene Gonçalves Costa de Souza, Adriele Vieira Batista, Jaqueline Pontes de Souza, Tállita Cristina Ferreira Caixeta, Douglas Carvalho Peixoto, Leonardo Gomes Teixeira, Renata Roland Espindola, Foued Salmen Puga, Guilherme Morais Zanesco, Angelina [UNESP] |
dc.subject.por.fl_str_mv |
Climacteric Combined exercise Nitrite Saliva Superoxide dismutase |
topic |
Climacteric Combined exercise Nitrite Saliva Superoxide dismutase |
description |
Aim: This study evaluated the effects of 10 weeks of combined exercise training on the salivary oxidative profile of hypertensive and normotensive postmenopausal women. Methods: Twenty-six non-obese postmenopausal women were divided into two groups: the hypertensive group (HT; n = 13; 58.9 ± 3.9 years; and BMI of 27.7 ± 4.6 kg/m2) or the normotensive group (NT; n = 13; 52.7 ± 5.2 years; and BMI of 26.9 ± 2.9 kg/m2). They performed 30 sessions of combined exercises over 10 weeks: 45 min per session, three times a week. Resting saliva samples were collected after an overnight fast to evaluate salivary nitrite levels and oxidative stress markers before and after training. Results: Two-way ANOVA showed that there was no difference in the responses over time between the hypertensive and normotensive groups in catalase, superoxide dismutase salivary activity, total antioxidant capacity, or lipid peroxidation. However, superoxide dismutase activity (ΔHT -0.87 ± 14.53 SOD/mg protein; ΔNT: 7.13 ± 9.39 SOD/mg protein; p < 0.01) and nitrite levels (ΔHT 10.32 ± 60.83 mM; ΔNT 101.92 ± 149.57 mM; p = 0.03) were higher overall in the hypertensive group compared to the normotensive group. Moreover, salivary nitrite levels increased over time (p = 0.04) in both groups. Conclusion: 10 weeks of combined exercise training did not change salivary oxidative stress markers in either normotensive or hypertensive postmenopausal women, although, after exercise training, nitrite levels increased in both groups, even with higher baseline salivary nitrite levels in hypertensive women. Thus, recurrent exercise seems to be a safe strategy after menopause from the standpoint of oxidative stress, regardless of the presence of hypertension. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-05-01T11:54:09Z 2022-05-01T11:54:09Z 2022-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1980-657420220012321 Motriz. Revista de Educacao Fisica, v. 28. 1980-6574 1415-9805 http://hdl.handle.net/11449/233952 10.1590/S1980-657420220012321 2-s2.0-85121985051 |
url |
http://dx.doi.org/10.1590/S1980-657420220012321 http://hdl.handle.net/11449/233952 |
identifier_str_mv |
Motriz. Revista de Educacao Fisica, v. 28. 1980-6574 1415-9805 10.1590/S1980-657420220012321 2-s2.0-85121985051 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Motriz. Revista de Educacao Fisica |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789796001644544 |