Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas

Detalhes bibliográficos
Autor(a) principal: De Nardi, A. B. [UNESP]
Data de Publicação: 2013
Outros Autores: Daleck, C. R. [UNESP], Amorin, R. L. [UNESP], Huppes, R. R. [UNESP], Uscategui, R. A. R. [UNESP], Rodaski, S., Calderon, C., Neto, R. T. [UNESP]
Tipo de documento: Artigo
Idioma: spa
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4067/S0301-732X2013000300012
http://hdl.handle.net/11449/111230
Resumo: The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P < 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.
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spelling Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomasCancerMammary neoplasmciclooxigenase-2DogThe aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P < 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.Univ Estadual Paulista, Dept Clin & Cirugia Vet, Sao Paulo, BrazilUniv Estadual Paulista, Dept Clin Vet, Sao Paulo, BrazilUniv Estadual Paulista, Programa Clin Vet, Sao Paulo, BrazilUniv Estadual Paulista, Programa Cirugia Vet, Sao Paulo, BrazilUniv Fed Parana, Dept Vet Med, BR-80060000 Curitiba, Parana, BrazilUniv Estadual Norte Parana, Bandeirantes, Parana, BrazilUniv Estadual Paulista, Dept Clin & Cirugia Vet, Sao Paulo, BrazilUniv Estadual Paulista, Dept Clin Vet, Sao Paulo, BrazilUniv Estadual Paulista, Programa Clin Vet, Sao Paulo, BrazilUniv Estadual Paulista, Programa Cirugia Vet, Sao Paulo, BrazilUniv Austral Chile, Fac Ciencias VeterinariasUniversidade Estadual Paulista (Unesp)Universidade Federal do Paraná (UFPR)Univ Estadual Norte ParanaDe Nardi, A. B. [UNESP]Daleck, C. R. [UNESP]Amorin, R. L. [UNESP]Huppes, R. R. [UNESP]Uscategui, R. A. R. [UNESP]Rodaski, S.Calderon, C.Neto, R. T. [UNESP]2014-12-03T13:07:05Z2014-12-03T13:07:05Z2013-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article311-316application/pdfhttp://dx.doi.org/10.4067/S0301-732X2013000300012Archivos De Medicina Veterinaria. Valdivia: Univ Austral Chile, Fac Ciencias Veterinarias, v. 45, n. 3, p. 311-316, 2013.0301-732Xhttp://hdl.handle.net/11449/11123010.4067/S0301-732X2013000300012WOS:000330203700011WOS000330203700011.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPspaArchivos de Medicina Veterinária0.236info:eu-repo/semantics/openAccess2023-12-19T06:23:50Zoai:repositorio.unesp.br:11449/111230Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-19T06:23:50Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
spellingShingle Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
De Nardi, A. B. [UNESP]
Cancer
Mammary neoplasm
ciclooxigenase-2
Dog
title_short Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title_full Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title_fullStr Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title_full_unstemmed Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
title_sort Cyclooxigenase-2 expression in primary metastatic and non metastatic canine mammarian carcinomas
author De Nardi, A. B. [UNESP]
author_facet De Nardi, A. B. [UNESP]
Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A. R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
author_role author
author2 Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A. R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Universidade Federal do Paraná (UFPR)
Univ Estadual Norte Parana
dc.contributor.author.fl_str_mv De Nardi, A. B. [UNESP]
Daleck, C. R. [UNESP]
Amorin, R. L. [UNESP]
Huppes, R. R. [UNESP]
Uscategui, R. A. R. [UNESP]
Rodaski, S.
Calderon, C.
Neto, R. T. [UNESP]
dc.subject.por.fl_str_mv Cancer
Mammary neoplasm
ciclooxigenase-2
Dog
topic Cancer
Mammary neoplasm
ciclooxigenase-2
Dog
description The aim of this study was to detect the expression of ciclooxigenase-2 (COX-2) in metastatic primary carcinoma and non metastatic carcinoma, taking into consideration the relation between COX-2 and the progression of cancer. Evaluation of the COX-2 expression was achieved by immunohistochemistry analysis, using the primary polyclonal antibody anti-PGHS-2, clone PG 27, (Oxford Biomedical Research). The number of marked cells by the COX-2 antibody was higher (P < 0.001) in the metastatic primary carcinoma (81.25%) than non-metastatic (60.3%). There was a positive correlation between the number of labeled cells.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
2014-12-03T13:07:05Z
2014-12-03T13:07:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4067/S0301-732X2013000300012
Archivos De Medicina Veterinaria. Valdivia: Univ Austral Chile, Fac Ciencias Veterinarias, v. 45, n. 3, p. 311-316, 2013.
0301-732X
http://hdl.handle.net/11449/111230
10.4067/S0301-732X2013000300012
WOS:000330203700011
WOS000330203700011.pdf
url http://dx.doi.org/10.4067/S0301-732X2013000300012
http://hdl.handle.net/11449/111230
identifier_str_mv Archivos De Medicina Veterinaria. Valdivia: Univ Austral Chile, Fac Ciencias Veterinarias, v. 45, n. 3, p. 311-316, 2013.
0301-732X
10.4067/S0301-732X2013000300012
WOS:000330203700011
WOS000330203700011.pdf
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv Archivos de Medicina Veterinária
0.236
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 311-316
application/pdf
dc.publisher.none.fl_str_mv Univ Austral Chile, Fac Ciencias Veterinarias
publisher.none.fl_str_mv Univ Austral Chile, Fac Ciencias Veterinarias
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1797790050394570752

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