Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving
Autor(a) principal: | |
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Data de Publicação: | 2017 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.2527/jas2017.1837 http://hdl.handle.net/11449/170372 |
Resumo: | One hundred eight Angus × Hereford steers, originating from 7 cow–calf were obtained from an auction yard on d −2 and transported by road (800 km; 12 h) to an experimental feedlot facility. Upon arrival on d −1, shrunk BW was recorded and steers were grouped with free-choice access to grass hay, mineral supplement, and water. On d 0, steers were ranked by source and shrunk BW and assigned to 1 of 18 pens (6 steers/pen). Pens were allocated to 1) no immunomodulatory ingredient supplementation during feedlot receiving (CON), 2) supplementation with OmniGen-AF (OMN; 22 g/steer daily, as-fed basis; Phibro Animal Health Corp., Teaneck, NJ) from d 0 to 30, or 3) 2 oral capsules of Stocker Immune Primer on d 0 + 15 g/ steer daily (as-fed basis) of Stocker Preconditioned Premix (Ramaekers Nutrition, Santa Cruz, CA) from d 7 to 30 (IPF). From d 0 to 80, steers had free-choice access to grass hay and water and received a corn-based concentrate. Feed DMI was recorded from each pen, and steers were assessed for bovine respiratory disease (BRD) signs daily. Steers were vaccinated against BRD pathogens on d 0 and 21. Final shrunk BW was recorded on d 81, and blood samples were collected on d 0, 3, 7, 10, 14, 21, 31, 42, 56, and 73. Steer ADG and final BW were greater (P ≤ 0.05) in CON steers than in OMN and IPF steers (1.23, 0.76, and 1.06 kg/d [SEM 0.06], respectively, and 320, 282, and 307 kg [SEM 4], respectively) and (P < 0.01) in IPF steers than in OMN steers. No treatment effects were detected (P ≥ 0.76) for BRD incidence (66 ± 4%) and DMI, whereas G:F was greater (P < 0.01) in OMN steers than in CON steers. Mean plasma cortisol concentration was greater (P = 0.01) in CON steers than in OMN and IPF steers. Plasma haptoglobin concentrations tended (P = 0.10) to be greater in CON steers than in IPF steers on d 3, were greater (P = 0.04) in IPF steers than in CON steers on d 7, and tended (P = 0.10) to be less in OMN steers than in IPF and CON steers on d 21. Blood mRNA expression of interleukin 8 was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 3 and in OMN steers than in CON and IPF steers on d 14. Blood mRNA expression of tumor necrosis-α was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 10. Plasma IGF-I concentrations, serum antibody titers to BRD pathogens, and blood mRNA expression of chemokine ligand 5, cyclooxygenase 2, interleukin 8 receptor, and L-selectin did not differ (P ≥ 0.21) among treatments. Collectively, the immunomodulatory feed ingredients evaluated herein impacted adrenocortical and innate immune responses but failed to mitigate BRD incidence and improve performance of receiving cattle. |
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Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receivingImmunomodulatory ingredientsInnate immunityPerformanceReceiving cattleRespiratory diseaseOne hundred eight Angus × Hereford steers, originating from 7 cow–calf were obtained from an auction yard on d −2 and transported by road (800 km; 12 h) to an experimental feedlot facility. Upon arrival on d −1, shrunk BW was recorded and steers were grouped with free-choice access to grass hay, mineral supplement, and water. On d 0, steers were ranked by source and shrunk BW and assigned to 1 of 18 pens (6 steers/pen). Pens were allocated to 1) no immunomodulatory ingredient supplementation during feedlot receiving (CON), 2) supplementation with OmniGen-AF (OMN; 22 g/steer daily, as-fed basis; Phibro Animal Health Corp., Teaneck, NJ) from d 0 to 30, or 3) 2 oral capsules of Stocker Immune Primer on d 0 + 15 g/ steer daily (as-fed basis) of Stocker Preconditioned Premix (Ramaekers Nutrition, Santa Cruz, CA) from d 7 to 30 (IPF). From d 0 to 80, steers had free-choice access to grass hay and water and received a corn-based concentrate. Feed DMI was recorded from each pen, and steers were assessed for bovine respiratory disease (BRD) signs daily. Steers were vaccinated against BRD pathogens on d 0 and 21. Final shrunk BW was recorded on d 81, and blood samples were collected on d 0, 3, 7, 10, 14, 21, 31, 42, 56, and 73. Steer ADG and final BW were greater (P ≤ 0.05) in CON steers than in OMN and IPF steers (1.23, 0.76, and 1.06 kg/d [SEM 0.06], respectively, and 320, 282, and 307 kg [SEM 4], respectively) and (P < 0.01) in IPF steers than in OMN steers. No treatment effects were detected (P ≥ 0.76) for BRD incidence (66 ± 4%) and DMI, whereas G:F was greater (P < 0.01) in OMN steers than in CON steers. Mean plasma cortisol concentration was greater (P = 0.01) in CON steers than in OMN and IPF steers. Plasma haptoglobin concentrations tended (P = 0.10) to be greater in CON steers than in IPF steers on d 3, were greater (P = 0.04) in IPF steers than in CON steers on d 7, and tended (P = 0.10) to be less in OMN steers than in IPF and CON steers on d 21. Blood mRNA expression of interleukin 8 was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 3 and in OMN steers than in CON and IPF steers on d 14. Blood mRNA expression of tumor necrosis-α was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 10. Plasma IGF-I concentrations, serum antibody titers to BRD pathogens, and blood mRNA expression of chemokine ligand 5, cyclooxygenase 2, interleukin 8 receptor, and L-selectin did not differ (P ≥ 0.21) among treatments. Collectively, the immunomodulatory feed ingredients evaluated herein impacted adrenocortical and innate immune responses but failed to mitigate BRD incidence and improve performance of receiving cattle.Oregon State University Eastern Oregon Agricultural Research CenterSão Paulo State University (UNESP) School of Veterinary Medicine and Animal ScienceTexas A&M University Department of Animal ScienceSão Paulo State University (UNESP) School of Veterinary Medicine and Animal ScienceEastern Oregon Agricultural Research CenterUniversidade Estadual Paulista (Unesp)Texas A&M UniversityLippolis, K. D.Cooke, R. F.Schumaher, T. [UNESP]Brandão, A. P.Silva, L. G.T. [UNESP]Schubach, K. M.Marques, R. S.Bohnert, D. W.2018-12-11T16:50:31Z2018-12-11T16:50:31Z2017-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article4945-4957application/pdfhttp://dx.doi.org/10.2527/jas2017.1837Journal of Animal Science, v. 95, n. 11, p. 4945-4957, 2017.1525-31630021-8812http://hdl.handle.net/11449/17037210.2527/jas2017.18372-s2.0-850337999262-s2.0-85033799926.pdfScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Animal Science0,848info:eu-repo/semantics/openAccess2023-11-18T06:17:48Zoai:repositorio.unesp.br:11449/170372Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-18T06:17:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
title |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
spellingShingle |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving Lippolis, K. D. Immunomodulatory ingredients Innate immunity Performance Receiving cattle Respiratory disease |
title_short |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
title_full |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
title_fullStr |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
title_full_unstemmed |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
title_sort |
Physiologic, health, and performance responses of beef steers supplemented with an immunomodulatory feed ingredient during feedlot receiving |
author |
Lippolis, K. D. |
author_facet |
Lippolis, K. D. Cooke, R. F. Schumaher, T. [UNESP] Brandão, A. P. Silva, L. G.T. [UNESP] Schubach, K. M. Marques, R. S. Bohnert, D. W. |
author_role |
author |
author2 |
Cooke, R. F. Schumaher, T. [UNESP] Brandão, A. P. Silva, L. G.T. [UNESP] Schubach, K. M. Marques, R. S. Bohnert, D. W. |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Eastern Oregon Agricultural Research Center Universidade Estadual Paulista (Unesp) Texas A&M University |
dc.contributor.author.fl_str_mv |
Lippolis, K. D. Cooke, R. F. Schumaher, T. [UNESP] Brandão, A. P. Silva, L. G.T. [UNESP] Schubach, K. M. Marques, R. S. Bohnert, D. W. |
dc.subject.por.fl_str_mv |
Immunomodulatory ingredients Innate immunity Performance Receiving cattle Respiratory disease |
topic |
Immunomodulatory ingredients Innate immunity Performance Receiving cattle Respiratory disease |
description |
One hundred eight Angus × Hereford steers, originating from 7 cow–calf were obtained from an auction yard on d −2 and transported by road (800 km; 12 h) to an experimental feedlot facility. Upon arrival on d −1, shrunk BW was recorded and steers were grouped with free-choice access to grass hay, mineral supplement, and water. On d 0, steers were ranked by source and shrunk BW and assigned to 1 of 18 pens (6 steers/pen). Pens were allocated to 1) no immunomodulatory ingredient supplementation during feedlot receiving (CON), 2) supplementation with OmniGen-AF (OMN; 22 g/steer daily, as-fed basis; Phibro Animal Health Corp., Teaneck, NJ) from d 0 to 30, or 3) 2 oral capsules of Stocker Immune Primer on d 0 + 15 g/ steer daily (as-fed basis) of Stocker Preconditioned Premix (Ramaekers Nutrition, Santa Cruz, CA) from d 7 to 30 (IPF). From d 0 to 80, steers had free-choice access to grass hay and water and received a corn-based concentrate. Feed DMI was recorded from each pen, and steers were assessed for bovine respiratory disease (BRD) signs daily. Steers were vaccinated against BRD pathogens on d 0 and 21. Final shrunk BW was recorded on d 81, and blood samples were collected on d 0, 3, 7, 10, 14, 21, 31, 42, 56, and 73. Steer ADG and final BW were greater (P ≤ 0.05) in CON steers than in OMN and IPF steers (1.23, 0.76, and 1.06 kg/d [SEM 0.06], respectively, and 320, 282, and 307 kg [SEM 4], respectively) and (P < 0.01) in IPF steers than in OMN steers. No treatment effects were detected (P ≥ 0.76) for BRD incidence (66 ± 4%) and DMI, whereas G:F was greater (P < 0.01) in OMN steers than in CON steers. Mean plasma cortisol concentration was greater (P = 0.01) in CON steers than in OMN and IPF steers. Plasma haptoglobin concentrations tended (P = 0.10) to be greater in CON steers than in IPF steers on d 3, were greater (P = 0.04) in IPF steers than in CON steers on d 7, and tended (P = 0.10) to be less in OMN steers than in IPF and CON steers on d 21. Blood mRNA expression of interleukin 8 was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 3 and in OMN steers than in CON and IPF steers on d 14. Blood mRNA expression of tumor necrosis-α was greater (P ≤ 0.05) in OMN and IPF steers than in CON steers on d 10. Plasma IGF-I concentrations, serum antibody titers to BRD pathogens, and blood mRNA expression of chemokine ligand 5, cyclooxygenase 2, interleukin 8 receptor, and L-selectin did not differ (P ≥ 0.21) among treatments. Collectively, the immunomodulatory feed ingredients evaluated herein impacted adrenocortical and innate immune responses but failed to mitigate BRD incidence and improve performance of receiving cattle. |
publishDate |
2017 |
dc.date.none.fl_str_mv |
2017-11-01 2018-12-11T16:50:31Z 2018-12-11T16:50:31Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.2527/jas2017.1837 Journal of Animal Science, v. 95, n. 11, p. 4945-4957, 2017. 1525-3163 0021-8812 http://hdl.handle.net/11449/170372 10.2527/jas2017.1837 2-s2.0-85033799926 2-s2.0-85033799926.pdf |
url |
http://dx.doi.org/10.2527/jas2017.1837 http://hdl.handle.net/11449/170372 |
identifier_str_mv |
Journal of Animal Science, v. 95, n. 11, p. 4945-4957, 2017. 1525-3163 0021-8812 10.2527/jas2017.1837 2-s2.0-85033799926 2-s2.0-85033799926.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Animal Science 0,848 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
4945-4957 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1797789749289680896 |