Toxoplasma gondii: I. Evaluation of the virulence of eight strains

Detalhes bibliográficos
Autor(a) principal: Mitsuka, Regina
Data de Publicação: 1998
Outros Autores: Beckner da Silva, Andrea Cristina, Navarro, Italmar Teodorico, Breganó, José Wander, Vidotto, Odilon
Tipo de documento: Artigo
Idioma: por
Título da fonte: Brazilian Journal of Veterinary Research and Animal Science
Texto Completo: https://www.revistas.usp.br/bjvras/article/view/5666
Resumo: In order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits.
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spelling Toxoplasma gondii: I. Evaluation of the virulence of eight strainsToxoplasma gondii: I. Avaliação da virulência de oito amostrasToxoplasma gondiiPatogenicidadeAnimais de laboratórioToxoplasma gondiiPathogenicityLaboratory animalsIn order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits.Oito amostras de T. gondii - LIV IV, LIV V e S 11 isoladas de suínos, RH e VPS de seres humanos, AS 28 de camundongo, HV III de cão e CN de gato - foram inoculadas em camundongos suíços albinos e em coelhos com o objetivo de avaliar a virulência e a patogenicidade. As oito amostras apresentaram-se altamente virulentas para camundongos, matando todos os animais que receberam inóculo, via intraperitoneal, de 10(4) taquizoítas, entre 6,0 e 7,8 dias, em média, após a inoculação. As amostras isoladas mais recentemente, LIV V e HV III (DL50 de 7 e 15 taquizoítas, respectivamente) foram as mais virulentas. A amostra RH foi a que apresentou a menor virulência, com DL50 de 3.160 taquizoítas. A amostra LIV V também se mostrou mais virulenta para coelhos, porém, como foram inoculados apenas 2 animais, estudos posteriores devem ser realizados para confirmar este achado.Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia1998-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/bjvras/article/view/566610.1590/S1413-95961998000100005Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 Núm. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 No. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; v. 35 n. 1 (1998); 29-31Brazilian Journal of Veterinary Research and Animal Science; V. 35 N. 1 (1998); 29-311678-44561413-9596reponame:Brazilian Journal of Veterinary Research and Animal Scienceinstname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)instacron:USPporhttps://www.revistas.usp.br/bjvras/article/view/5666/7197Mitsuka, ReginaBeckner da Silva, Andrea CristinaNavarro, Italmar TeodoricoBreganó, José WanderVidotto, Odiloninfo:eu-repo/semantics/openAccess2020-06-23T04:46:43Zoai:revistas.usp.br:article/5666Revistahttps://www.revistas.usp.br/bjvrasPUBhttps://www.revistas.usp.br/bjvras/oaibjvras@usp.br1413-95961413-9596opendoar:https://www.revistas.usp.br/bjvras/index2023-01-12T16:42:16.198221Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)false
dc.title.none.fl_str_mv Toxoplasma gondii: I. Evaluation of the virulence of eight strains
Toxoplasma gondii: I. Avaliação da virulência de oito amostras
title Toxoplasma gondii: I. Evaluation of the virulence of eight strains
spellingShingle Toxoplasma gondii: I. Evaluation of the virulence of eight strains
Mitsuka, Regina
Toxoplasma gondii
Patogenicidade
Animais de laboratório
Toxoplasma gondii
Pathogenicity
Laboratory animals
title_short Toxoplasma gondii: I. Evaluation of the virulence of eight strains
title_full Toxoplasma gondii: I. Evaluation of the virulence of eight strains
title_fullStr Toxoplasma gondii: I. Evaluation of the virulence of eight strains
title_full_unstemmed Toxoplasma gondii: I. Evaluation of the virulence of eight strains
title_sort Toxoplasma gondii: I. Evaluation of the virulence of eight strains
author Mitsuka, Regina
author_facet Mitsuka, Regina
Beckner da Silva, Andrea Cristina
Navarro, Italmar Teodorico
Breganó, José Wander
Vidotto, Odilon
author_role author
author2 Beckner da Silva, Andrea Cristina
Navarro, Italmar Teodorico
Breganó, José Wander
Vidotto, Odilon
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Mitsuka, Regina
Beckner da Silva, Andrea Cristina
Navarro, Italmar Teodorico
Breganó, José Wander
Vidotto, Odilon
dc.subject.por.fl_str_mv Toxoplasma gondii
Patogenicidade
Animais de laboratório
Toxoplasma gondii
Pathogenicity
Laboratory animals
topic Toxoplasma gondii
Patogenicidade
Animais de laboratório
Toxoplasma gondii
Pathogenicity
Laboratory animals
description In order to evaluate the virulence and pathogenicity of tachyzoites, eight Toxoplasma gondii strains isolated from different animal species and humans - LIV IV, LIV V e S 11 isolated from swine, RH e VPS from humans, AS 28 from mice, HV III from dog and CN from cat - were inoculated in mice and rabbits. All the strains were strongly virulent for mice. Groups of mice inoculated, intraperitonially, with 10(4) tachyzoites died in an average of 6.0 to 7.8 days, after inoculation. The strains isolated more recently, LIV V and HV III (LD50 of 7 and 15 tachyzoites, respectively) were the most virulent. The RH strain showed the lowest virulence, with LD50 of 3160 tachyzoites. The LIV V strain also seems to be most virulent to rabbits.
publishDate 1998
dc.date.none.fl_str_mv 1998-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5666
10.1590/S1413-95961998000100005
url https://www.revistas.usp.br/bjvras/article/view/5666
identifier_str_mv 10.1590/S1413-95961998000100005
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://www.revistas.usp.br/bjvras/article/view/5666/7197
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
publisher.none.fl_str_mv Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia
dc.source.none.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 Núm. 1 (1998); 29-31
Brazilian Journal of Veterinary Research and Animal Science; Vol. 35 No. 1 (1998); 29-31
Brazilian Journal of Veterinary Research and Animal Science; v. 35 n. 1 (1998); 29-31
Brazilian Journal of Veterinary Research and Animal Science; V. 35 N. 1 (1998); 29-31
1678-4456
1413-9596
reponame:Brazilian Journal of Veterinary Research and Animal Science
instname:Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron:USP
instname_str Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
instacron_str USP
institution USP
reponame_str Brazilian Journal of Veterinary Research and Animal Science
collection Brazilian Journal of Veterinary Research and Animal Science
repository.name.fl_str_mv Brazilian Journal of Veterinary Research and Animal Science - Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (FMVZ-USP)
repository.mail.fl_str_mv bjvras@usp.br
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