Fatores associados à adesão ao tratamento dos pacientes com fenilcetonúria atendidos no Hospital Infantil Joana de Gusmão

• Autor(a) principal: Mariosa, Nayara Ferreira
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Universitário da Ânima (RUNA)
• Texto Completo: https://repositorio.animaeducacao.com.br/handle/ANIMA/9446
• topic: Fenilcetonúria; Fenilalanina; Adesão; Tratamento

Introduction: Phenylketonuria (PKU) is a disease of autosomal genetic inheritance which promotes a change in the metabolism of amino acids with increased phenylalanine (phe) in the blood and impairment in cellular communication. Adherence to treatment linked to the maintenance of a restricted diet in phenylalanine and control of metabolic levels, is a great challenge with high impact on family quality of life. Objectives: To analyze the factors associated with adherence to the treatment of patients with Phenylketonuria treated at the Hospital Joana de Gusmão - Florianópolis - SC, in the period between August 2015 and November 2016. Method: Cross-sectional observational study with case-control type analysis. Data from patients between 0 and 41 years of age were collected and analyzed from 50 charts, and interviews were conducted with those who were responsible for the patients. Approved in CEP Unisul. Results: The prevalence of adherence to treatment was 52.2% in patients younger than 13 years of age, 92.3% of patients adhering to treatment started treatment in childhood, 41.7% of those responsible for the patients, adhering to treatment, have more than 8 years of schooling and 75% reported on government failure to provide the formula. Conclusion: The treatment adherence depends on demographic factors like the age of the patients, as well the early beginning of treatment, well known about phenylketonuria and the adequate supply of the metabolic formula, that can contribute for the maintenance of phenylalanine levels.