Fatores associados à neoplasia não invasiva de alto grau em pólipos adenomatosos de pacientes que realizaram colonoscopia por indicação de rastreamento de carcinoma colorretal

• Autor(a) principal: Souza, Julia Koerich de
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Universitário da Ânima (RUNA)
• Texto Completo: https://repositorio.animaeducacao.com.br/handle/ANIMA/9248
• topic: Colonoscopia; Pólipos adenomatosos; Fatores de risco; Neoplasias colorretais

Introduction: Intestinal adenomatous polyps are precursor lesions of colorectal carcinoma (CRC), one of the most common types of cancer among men and women. Screening and appropriate treatment of polyps is able to reduce incidence and mortality by CRC. Objective: To identify the factors associated with high-grade neoplasia in adenomatous polyps of patients 50 years of age or older who underwent colonoscopy for CRC screening. Methods: Case-control study with 216 individuals with adenomatous polyps who underwent colonoscopy in private practice in Florianópolis, separated in two groups according to the presence or absence of high grade neoplasia. Data obtained from electronic medical records. Statistical analysis SPSS 18.0, Chi-square test, and p≤0.05. Oddis Ratio (OR) with 95% CI. Approved by CEP UNISUL. Results: There was no statistically significant relationship between sex; Age; Genre; Family history; Previous polypectomies; Number of polyps; And high-grade neoplasia. Weak association with non-polypoid morphology (OR=2,875 and p=0,051) and statistical significance with polyp size ≥1cm (OR=26.147 and p<0.01), villous or tubulo-villous histology (OR=7 and p <0.01) and location of the polyp in the left colon (OR=37.766 and p<0.01). Conclusion: The factors associated with high-grade neoplasia in colon adenomas include polyp size greater than or equal to 1 cm, villous or tubulo-villous histology, the location of the polyp in the left colon, and non-polypoid morphology.