Associação entre sintomas depressivos e capacidade cognitiva em pessoas com 50 anos ou mais atendidas em um ambulatório da memória

• Autor(a) principal: Tavares, Sarah Karolina Lima
• Data de Publicação: 2017
• Tipo de documento: Trabalho de conclusão de curso
• Idioma: por
• Título da fonte: Repositório Universitário da Ânima (RUNA)
• Texto Completo: https://repositorio.animaeducacao.com.br/handle/ANIMA/9265
• topic: Ambulatório da memória; Capacidade cognitiva; Depressão; MoCA teste; Escala de Depressão Geriátrica - 15

Introduction: Depression is a modifiable risk factor for cognitive decline and dementia, depressed people improve their cognitive ability after successful treatment. Objective: To identify the association between depressive symptoms evaluated by the Geriatric Depression Scale version 15 (GDS 15) in relation to the cognitive status measured by the Montreal Cognitive Assessment (MoCA) Test in patients with 50 years or more of an outpatient memory clinic. Method: An exploratory cohort study, with 154 patients followed at the outpatient memory clinic of the Medical Specialties Ambulatory (AME / UNISUL). The main predictor was the GDS variation between the first (entrance) and second interview in the outpatient clinic and the main outcome was the MoCA variation in the same period. The analysis was univariate, bivariate using the Chi-square test and Student's T test for independent and paired samples; the final multivariate model was obtained by linear regression. Results: white color (90.9%); female gender (85.1%); Diabetes (74.0%); Hypothyroidism (84.4%); Depression (47.4%). The diagnosis of hypothyroidism was associated with the variation of the MoCA test (p = 0.025). Conclusion: In relation to the total sample, the presence of hypothyroidism was associated with the variation in the outcome studied. There was a significant reduction in the number of participants in a major depressive episode and an increase in the number of people with a remission of a depressive episode according to GDS. The variation (improvement) in GDS scores between the first and second interviews was significantly associated with variation (improvement) in MoCA only among those who had previously diagnosed depression.Among non-depressed individuals, there was no association between depressive symptoms and cognitive ability.