Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors

Detalhes bibliográficos
Autor(a) principal: TORRÃO,ANDRÉA S.
Data de Publicação: 2002
Outros Autores: BRITTO,LUIZ R.G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300008
Resumo: Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be unrelated to their role in cholinergic neurotransmission in the vertebrate brain. Both temporal expression data and in vitro and in vivo studies with nicotinic agonists and antagonists have provided direct support for a role of nicotinic receptors in neural developmental processes such as neurite outgrowth and differentiation. A similar picture has emerged for other neurotransmitter and receptor systems as well, which generates a new view of neural processes during both development and mature life.
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spelling Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptorsacetylcholinedevelopmentneurotransmittersnicotinenicotinic receptorsSeveral neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be unrelated to their role in cholinergic neurotransmission in the vertebrate brain. Both temporal expression data and in vitro and in vivo studies with nicotinic agonists and antagonists have provided direct support for a role of nicotinic receptors in neural developmental processes such as neurite outgrowth and differentiation. A similar picture has emerged for other neurotransmitter and receptor systems as well, which generates a new view of neural processes during both development and mature life.Academia Brasileira de Ciências2002-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300008Anais da Academia Brasileira de Ciências v.74 n.3 2002reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652002000300008info:eu-repo/semantics/openAccessTORRÃO,ANDRÉA S.BRITTO,LUIZ R.G.eng2002-10-09T00:00:00Zoai:scielo:S0001-37652002000300008Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2002-10-09T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
title Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
spellingShingle Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
TORRÃO,ANDRÉA S.
acetylcholine
development
neurotransmitters
nicotine
nicotinic receptors
title_short Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
title_full Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
title_fullStr Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
title_full_unstemmed Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
title_sort Neurotransmitter regulation of neural development: acetylcholine and nicotinic receptors
author TORRÃO,ANDRÉA S.
author_facet TORRÃO,ANDRÉA S.
BRITTO,LUIZ R.G.
author_role author
author2 BRITTO,LUIZ R.G.
author2_role author
dc.contributor.author.fl_str_mv TORRÃO,ANDRÉA S.
BRITTO,LUIZ R.G.
dc.subject.por.fl_str_mv acetylcholine
development
neurotransmitters
nicotine
nicotinic receptors
topic acetylcholine
development
neurotransmitters
nicotine
nicotinic receptors
description Several neurotransmitter systems have been related to developmental processes during the past decade. In this review, we discuss the evidence that the nicotinic acetylcholine receptors could have an additional function during development that may be unrelated to their role in cholinergic neurotransmission in the vertebrate brain. Both temporal expression data and in vitro and in vivo studies with nicotinic agonists and antagonists have provided direct support for a role of nicotinic receptors in neural developmental processes such as neurite outgrowth and differentiation. A similar picture has emerged for other neurotransmitter and receptor systems as well, which generates a new view of neural processes during both development and mature life.
publishDate 2002
dc.date.none.fl_str_mv 2002-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300008
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000300008
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0001-37652002000300008
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.74 n.3 2002
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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