Antarctic organisms as a source of antimicrobial compounds: a patent review
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais da Academia Brasileira de Ciências (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000200909 |
Resumo: | Abstract Currently, antimicrobial resistance has become a global public health problem, which has made the need for new antimicrobial compounds to deal with resistant infections an emergency. However, environments that once offered so many innovative molecules, now already exhaustively exploited, do not meet this need. In this context, a geographically isolated, under-explored and extreme environment, such as Antarctica, which holds organisms with unique physiological and biochemical characteristics, assumes great importance as a potential source of new compounds with antimicrobial activity. In this patent review, we investigate the state of technological development in the field of antimicrobial compounds obtained from Antarctic organisms, highlighting the main countries and researchers active in the field, the species utilized, the compounds obtained, and their possible therapeutic applications. As results, few patent documents were found, however they encompass a wide diversity of compounds and species, indicating a great antimicrobial potential present in Antarctic biota, including compounds active against the most important human pathogenic microorganisms, such as including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp. and multi-resistant Mycobacterium tuberculosis. Furthermore, due to the increasing trend in patent applications, a significant rise in the number of patents in this area is expected in the coming years. |
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Antarctic organisms as a source of antimicrobial compounds: a patent reviewAntarcticaantimicrobial activityantimicrobial resistancenatural antimicrobialssecondary metabolitesAbstract Currently, antimicrobial resistance has become a global public health problem, which has made the need for new antimicrobial compounds to deal with resistant infections an emergency. However, environments that once offered so many innovative molecules, now already exhaustively exploited, do not meet this need. In this context, a geographically isolated, under-explored and extreme environment, such as Antarctica, which holds organisms with unique physiological and biochemical characteristics, assumes great importance as a potential source of new compounds with antimicrobial activity. In this patent review, we investigate the state of technological development in the field of antimicrobial compounds obtained from Antarctic organisms, highlighting the main countries and researchers active in the field, the species utilized, the compounds obtained, and their possible therapeutic applications. As results, few patent documents were found, however they encompass a wide diversity of compounds and species, indicating a great antimicrobial potential present in Antarctic biota, including compounds active against the most important human pathogenic microorganisms, such as including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp. and multi-resistant Mycobacterium tuberculosis. Furthermore, due to the increasing trend in patent applications, a significant rise in the number of patents in this area is expected in the coming years.Academia Brasileira de Ciências2022-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000200909Anais da Academia Brasileira de Ciências v.94 suppl.1 2022reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765202220210840info:eu-repo/semantics/openAccessSILVA,MAURÍCIO B.FEITOSA,ALEXYA O.LIMA,IGOR G.O.BISPO,JAMES R.S.SANTOS,ANA CAROLINE M.MOREIRA,MAGNA S.A.CÂMARA,PAULO E.A.S.ROSA,LUIZ HENRIQUEOLIVEIRA,VALÉRIA M.DUARTE,ALYSSON W.F.QUEIROZ,ALINE C.eng2022-04-05T00:00:00Zoai:scielo:S0001-37652022000200909Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2022-04-05T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false |
dc.title.none.fl_str_mv |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
title |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
spellingShingle |
Antarctic organisms as a source of antimicrobial compounds: a patent review SILVA,MAURÍCIO B. Antarctica antimicrobial activity antimicrobial resistance natural antimicrobials secondary metabolites |
title_short |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
title_full |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
title_fullStr |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
title_full_unstemmed |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
title_sort |
Antarctic organisms as a source of antimicrobial compounds: a patent review |
author |
SILVA,MAURÍCIO B. |
author_facet |
SILVA,MAURÍCIO B. FEITOSA,ALEXYA O. LIMA,IGOR G.O. BISPO,JAMES R.S. SANTOS,ANA CAROLINE M. MOREIRA,MAGNA S.A. CÂMARA,PAULO E.A.S. ROSA,LUIZ HENRIQUE OLIVEIRA,VALÉRIA M. DUARTE,ALYSSON W.F. QUEIROZ,ALINE C. |
author_role |
author |
author2 |
FEITOSA,ALEXYA O. LIMA,IGOR G.O. BISPO,JAMES R.S. SANTOS,ANA CAROLINE M. MOREIRA,MAGNA S.A. CÂMARA,PAULO E.A.S. ROSA,LUIZ HENRIQUE OLIVEIRA,VALÉRIA M. DUARTE,ALYSSON W.F. QUEIROZ,ALINE C. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
SILVA,MAURÍCIO B. FEITOSA,ALEXYA O. LIMA,IGOR G.O. BISPO,JAMES R.S. SANTOS,ANA CAROLINE M. MOREIRA,MAGNA S.A. CÂMARA,PAULO E.A.S. ROSA,LUIZ HENRIQUE OLIVEIRA,VALÉRIA M. DUARTE,ALYSSON W.F. QUEIROZ,ALINE C. |
dc.subject.por.fl_str_mv |
Antarctica antimicrobial activity antimicrobial resistance natural antimicrobials secondary metabolites |
topic |
Antarctica antimicrobial activity antimicrobial resistance natural antimicrobials secondary metabolites |
description |
Abstract Currently, antimicrobial resistance has become a global public health problem, which has made the need for new antimicrobial compounds to deal with resistant infections an emergency. However, environments that once offered so many innovative molecules, now already exhaustively exploited, do not meet this need. In this context, a geographically isolated, under-explored and extreme environment, such as Antarctica, which holds organisms with unique physiological and biochemical characteristics, assumes great importance as a potential source of new compounds with antimicrobial activity. In this patent review, we investigate the state of technological development in the field of antimicrobial compounds obtained from Antarctic organisms, highlighting the main countries and researchers active in the field, the species utilized, the compounds obtained, and their possible therapeutic applications. As results, few patent documents were found, however they encompass a wide diversity of compounds and species, indicating a great antimicrobial potential present in Antarctic biota, including compounds active against the most important human pathogenic microorganisms, such as including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus spp. and multi-resistant Mycobacterium tuberculosis. Furthermore, due to the increasing trend in patent applications, a significant rise in the number of patents in this area is expected in the coming years. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000200909 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652022000200909 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0001-3765202220210840 |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências v.94 suppl.1 2022 reponame:Anais da Academia Brasileira de Ciências (Online) instname:Academia Brasileira de Ciências (ABC) instacron:ABC |
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Academia Brasileira de Ciências (ABC) |
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ABC |
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ABC |
reponame_str |
Anais da Academia Brasileira de Ciências (Online) |
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Anais da Academia Brasileira de Ciências (Online) |
repository.name.fl_str_mv |
Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC) |
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||aabc@abc.org.br |
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