A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein

Detalhes bibliográficos
Autor(a) principal: Oliveira Neto,Osmundo B.
Data de Publicação: 2012
Outros Autores: Farias,Davi F., Vasconcelos,Ilka M., Paes,Norma S., Monteiro,Ana C. S., Silva,Maria C. M. da, Guimarães,Luciane M., Carvalho,Ana F.U., Grossi-de-Sá,Maria F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100019
Resumo: Chagasin may be considered a potential plant-incorporated protectant (PIP) protein due to its deleterious effects on insect pests. However, extensive safety studies with PIP's are necessary before introducing them into the target plant. Thus, a short-term feeding trial in rats with high doses of r-chagasin was conducted to provide evidences about its safety. Three test diets containing casein + r-chagasin (0.25, 0.5 and 1% of total protein) were offered to rats (10 days). The test diets did not show adverse effects upon the development, organ weight, hematological parameters and serum protein profiles of rats, providing preliminary information on the safety of r-chagasin.
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spelling A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense proteinchagasinrecombinant proteinhazard potentialshort-term rat feeding trialChagasin may be considered a potential plant-incorporated protectant (PIP) protein due to its deleterious effects on insect pests. However, extensive safety studies with PIP's are necessary before introducing them into the target plant. Thus, a short-term feeding trial in rats with high doses of r-chagasin was conducted to provide evidences about its safety. Three test diets containing casein + r-chagasin (0.25, 0.5 and 1% of total protein) were offered to rats (10 days). The test diets did not show adverse effects upon the development, organ weight, hematological parameters and serum protein profiles of rats, providing preliminary information on the safety of r-chagasin.Academia Brasileira de Ciências2012-03-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100019Anais da Academia Brasileira de Ciências v.84 n.1 2012reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/S0001-37652012005000005info:eu-repo/semantics/openAccessOliveira Neto,Osmundo B.Farias,Davi F.Vasconcelos,Ilka M.Paes,Norma S.Monteiro,Ana C. S.Silva,Maria C. M. daGuimarães,Luciane M.Carvalho,Ana F.U.Grossi-de-Sá,Maria F.eng2012-05-22T00:00:00Zoai:scielo:S0001-37652012000100019Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2012-05-22T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
title A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
spellingShingle A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
Oliveira Neto,Osmundo B.
chagasin
recombinant protein
hazard potential
short-term rat feeding trial
title_short A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
title_full A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
title_fullStr A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
title_full_unstemmed A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
title_sort A brief report on some health aspects of rats fed with crescent levels of recombinant chagasin, a potential plant defense protein
author Oliveira Neto,Osmundo B.
author_facet Oliveira Neto,Osmundo B.
Farias,Davi F.
Vasconcelos,Ilka M.
Paes,Norma S.
Monteiro,Ana C. S.
Silva,Maria C. M. da
Guimarães,Luciane M.
Carvalho,Ana F.U.
Grossi-de-Sá,Maria F.
author_role author
author2 Farias,Davi F.
Vasconcelos,Ilka M.
Paes,Norma S.
Monteiro,Ana C. S.
Silva,Maria C. M. da
Guimarães,Luciane M.
Carvalho,Ana F.U.
Grossi-de-Sá,Maria F.
author2_role author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Oliveira Neto,Osmundo B.
Farias,Davi F.
Vasconcelos,Ilka M.
Paes,Norma S.
Monteiro,Ana C. S.
Silva,Maria C. M. da
Guimarães,Luciane M.
Carvalho,Ana F.U.
Grossi-de-Sá,Maria F.
dc.subject.por.fl_str_mv chagasin
recombinant protein
hazard potential
short-term rat feeding trial
topic chagasin
recombinant protein
hazard potential
short-term rat feeding trial
description Chagasin may be considered a potential plant-incorporated protectant (PIP) protein due to its deleterious effects on insect pests. However, extensive safety studies with PIP's are necessary before introducing them into the target plant. Thus, a short-term feeding trial in rats with high doses of r-chagasin was conducted to provide evidences about its safety. Three test diets containing casein + r-chagasin (0.25, 0.5 and 1% of total protein) were offered to rats (10 days). The test diets did not show adverse effects upon the development, organ weight, hematological parameters and serum protein profiles of rats, providing preliminary information on the safety of r-chagasin.
publishDate 2012
dc.date.none.fl_str_mv 2012-03-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100019
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652012000100019
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0001-37652012005000005
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.84 n.1 2012
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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