Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil

Detalhes bibliográficos
Autor(a) principal: ALVES,VANESSA G.
Data de Publicação: 2016
Outros Autores: SOUZA,ALAN G., CHIAVELLI,LUCAS U.R., RUIZ,ANA L.T.G., CARVALHO,JOÃO E., POMINI,ARMANDO M., SILVA,CLEUZA C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401201
Resumo: ABSTRACT The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates.
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spelling Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazilanticancer activityphenolic compoundsSaccharum officinarum L.sugarcane.ABSTRACT The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates.Academia Brasileira de Ciências2016-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401201Anais da Academia Brasileira de Ciências v.88 n.3 2016reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201620150349info:eu-repo/semantics/openAccessALVES,VANESSA G.SOUZA,ALAN G.CHIAVELLI,LUCAS U.R.RUIZ,ANA L.T.G.CARVALHO,JOÃO E.POMINI,ARMANDO M.SILVA,CLEUZA C.eng2016-09-12T00:00:00Zoai:scielo:S0001-37652016000401201Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2016-09-12T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
title Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
spellingShingle Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
ALVES,VANESSA G.
anticancer activity
phenolic compounds
Saccharum officinarum L.
sugarcane.
title_short Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
title_full Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
title_fullStr Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
title_full_unstemmed Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
title_sort Phenolic compounds and anticancer activity of commercial sugarcane cultivated in Brazil
author ALVES,VANESSA G.
author_facet ALVES,VANESSA G.
SOUZA,ALAN G.
CHIAVELLI,LUCAS U.R.
RUIZ,ANA L.T.G.
CARVALHO,JOÃO E.
POMINI,ARMANDO M.
SILVA,CLEUZA C.
author_role author
author2 SOUZA,ALAN G.
CHIAVELLI,LUCAS U.R.
RUIZ,ANA L.T.G.
CARVALHO,JOÃO E.
POMINI,ARMANDO M.
SILVA,CLEUZA C.
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv ALVES,VANESSA G.
SOUZA,ALAN G.
CHIAVELLI,LUCAS U.R.
RUIZ,ANA L.T.G.
CARVALHO,JOÃO E.
POMINI,ARMANDO M.
SILVA,CLEUZA C.
dc.subject.por.fl_str_mv anticancer activity
phenolic compounds
Saccharum officinarum L.
sugarcane.
topic anticancer activity
phenolic compounds
Saccharum officinarum L.
sugarcane.
description ABSTRACT The cultivation of sugarcane hybrids (X Saccharum officinarum L.) is an important revenue source for the Brazilian economy. Herein it is reported the evaluation of the cytotoxic activity of mid-polarity sugarcane extracts against human cancer cell lines, as well as the isolation of steroids sitosterol, stigmasterol and campesterol, phenolic acids p-hydroxybenzoic, p-hydroxycinnamic, vanillic and ferulic acid, terpenoids α-tocopherol and β-carotene and a novel substance in sugarcane, the flavonoid aglycone tricin (5,7,4-trihydroxy-3,5-dimethoxyflavone). The presence of large amounts of phenolic acids and the flavonoid tricin may explain the cytostatic activity observed for the mid-polarity crude extract and filtrates.
publishDate 2016
dc.date.none.fl_str_mv 2016-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401201
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652016000401201
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765201620150349
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.88 n.3 2016
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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