A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats

Detalhes bibliográficos
Autor(a) principal: CEOLIN,PATRÍCIA
Data de Publicação: 2019
Outros Autores: FRANÇA,SUÉLEM A. DE, FROELICH,MENDALLI, SANTOS,MAÍSA P. DOS, PEREIRA,MAYARA P., QUEIROZ,THAÍS S., SILVA,FLÁVIA H.S. DA, LISBOA,PATRÍCIA C., ANDRADE,CLAUDIA M.B., BAVIERA,AMANDA M., KAWASHITA,NAIR H.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Anais da Academia Brasileira de Ciências (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714
Resumo: Abstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin.
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spelling A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in ratslow-proteinhigh-carbohydrate dietpost-weaning periodHOMA-IRadiponectinAbstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin.Academia Brasileira de Ciências2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714Anais da Academia Brasileira de Ciências v.91 n.2 2019reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201920180452info:eu-repo/semantics/openAccessCEOLIN,PATRÍCIAFRANÇA,SUÉLEM A. DEFROELICH,MENDALLISANTOS,MAÍSA P. DOSPEREIRA,MAYARA P.QUEIROZ,THAÍS S.SILVA,FLÁVIA H.S. DALISBOA,PATRÍCIA C.ANDRADE,CLAUDIA M.B.BAVIERA,AMANDA M.KAWASHITA,NAIR H.eng2019-06-27T00:00:00Zoai:scielo:S0001-37652019000300714Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2019-06-27T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false
dc.title.none.fl_str_mv A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
title A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
spellingShingle A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
CEOLIN,PATRÍCIA
low-protein
high-carbohydrate diet
post-weaning period
HOMA-IR
adiponectin
title_short A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
title_full A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
title_fullStr A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
title_full_unstemmed A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
title_sort A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
author CEOLIN,PATRÍCIA
author_facet CEOLIN,PATRÍCIA
FRANÇA,SUÉLEM A. DE
FROELICH,MENDALLI
SANTOS,MAÍSA P. DOS
PEREIRA,MAYARA P.
QUEIROZ,THAÍS S.
SILVA,FLÁVIA H.S. DA
LISBOA,PATRÍCIA C.
ANDRADE,CLAUDIA M.B.
BAVIERA,AMANDA M.
KAWASHITA,NAIR H.
author_role author
author2 FRANÇA,SUÉLEM A. DE
FROELICH,MENDALLI
SANTOS,MAÍSA P. DOS
PEREIRA,MAYARA P.
QUEIROZ,THAÍS S.
SILVA,FLÁVIA H.S. DA
LISBOA,PATRÍCIA C.
ANDRADE,CLAUDIA M.B.
BAVIERA,AMANDA M.
KAWASHITA,NAIR H.
author2_role author
author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv CEOLIN,PATRÍCIA
FRANÇA,SUÉLEM A. DE
FROELICH,MENDALLI
SANTOS,MAÍSA P. DOS
PEREIRA,MAYARA P.
QUEIROZ,THAÍS S.
SILVA,FLÁVIA H.S. DA
LISBOA,PATRÍCIA C.
ANDRADE,CLAUDIA M.B.
BAVIERA,AMANDA M.
KAWASHITA,NAIR H.
dc.subject.por.fl_str_mv low-protein
high-carbohydrate diet
post-weaning period
HOMA-IR
adiponectin
topic low-protein
high-carbohydrate diet
post-weaning period
HOMA-IR
adiponectin
description Abstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin.
publishDate 2019
dc.date.none.fl_str_mv 2019-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/0001-3765201920180452
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Academia Brasileira de Ciências
publisher.none.fl_str_mv Academia Brasileira de Ciências
dc.source.none.fl_str_mv Anais da Academia Brasileira de Ciências v.91 n.2 2019
reponame:Anais da Academia Brasileira de Ciências (Online)
instname:Academia Brasileira de Ciências (ABC)
instacron:ABC
instname_str Academia Brasileira de Ciências (ABC)
instacron_str ABC
institution ABC
reponame_str Anais da Academia Brasileira de Ciências (Online)
collection Anais da Academia Brasileira de Ciências (Online)
repository.name.fl_str_mv Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)
repository.mail.fl_str_mv ||aabc@abc.org.br
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