A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Anais da Academia Brasileira de Ciências (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714 |
Resumo: | Abstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin. |
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A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in ratslow-proteinhigh-carbohydrate dietpost-weaning periodHOMA-IRadiponectinAbstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin.Academia Brasileira de Ciências2019-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714Anais da Academia Brasileira de Ciências v.91 n.2 2019reponame:Anais da Academia Brasileira de Ciências (Online)instname:Academia Brasileira de Ciências (ABC)instacron:ABC10.1590/0001-3765201920180452info:eu-repo/semantics/openAccessCEOLIN,PATRÍCIAFRANÇA,SUÉLEM A. DEFROELICH,MENDALLISANTOS,MAÍSA P. DOSPEREIRA,MAYARA P.QUEIROZ,THAÍS S.SILVA,FLÁVIA H.S. DALISBOA,PATRÍCIA C.ANDRADE,CLAUDIA M.B.BAVIERA,AMANDA M.KAWASHITA,NAIR H.eng2019-06-27T00:00:00Zoai:scielo:S0001-37652019000300714Revistahttp://www.scielo.br/aabchttps://old.scielo.br/oai/scielo-oai.php||aabc@abc.org.br1678-26900001-3765opendoar:2019-06-27T00:00Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC)false |
dc.title.none.fl_str_mv |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
title |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
spellingShingle |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats CEOLIN,PATRÍCIA low-protein high-carbohydrate diet post-weaning period HOMA-IR adiponectin |
title_short |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
title_full |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
title_fullStr |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
title_full_unstemmed |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
title_sort |
A low-protein, high carbohydrate diet induces increase in serum adiponectin and preserves glucose homeostasis in rats |
author |
CEOLIN,PATRÍCIA |
author_facet |
CEOLIN,PATRÍCIA FRANÇA,SUÉLEM A. DE FROELICH,MENDALLI SANTOS,MAÍSA P. DOS PEREIRA,MAYARA P. QUEIROZ,THAÍS S. SILVA,FLÁVIA H.S. DA LISBOA,PATRÍCIA C. ANDRADE,CLAUDIA M.B. BAVIERA,AMANDA M. KAWASHITA,NAIR H. |
author_role |
author |
author2 |
FRANÇA,SUÉLEM A. DE FROELICH,MENDALLI SANTOS,MAÍSA P. DOS PEREIRA,MAYARA P. QUEIROZ,THAÍS S. SILVA,FLÁVIA H.S. DA LISBOA,PATRÍCIA C. ANDRADE,CLAUDIA M.B. BAVIERA,AMANDA M. KAWASHITA,NAIR H. |
author2_role |
author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
CEOLIN,PATRÍCIA FRANÇA,SUÉLEM A. DE FROELICH,MENDALLI SANTOS,MAÍSA P. DOS PEREIRA,MAYARA P. QUEIROZ,THAÍS S. SILVA,FLÁVIA H.S. DA LISBOA,PATRÍCIA C. ANDRADE,CLAUDIA M.B. BAVIERA,AMANDA M. KAWASHITA,NAIR H. |
dc.subject.por.fl_str_mv |
low-protein high-carbohydrate diet post-weaning period HOMA-IR adiponectin |
topic |
low-protein high-carbohydrate diet post-weaning period HOMA-IR adiponectin |
description |
Abstract: The aim of this study was investigate the effects of a low-protein, high-carbohydrate (LPHC) diet introduced to rats soon after weaning. The animals were distributed in the following groups: LPHC45: fed an LPHC diet (6%-protein, 74%-carbohydrate) for 45 days; C45: fed a control (C) diet (17%-protein, 63%-carbohydrate) for 45 days; R (Reverse): fed with LPHC for 15 days followed by C diet for 30 days. The LPHC45 group showed alterations in the energetic balance with an increase in brown adipose tissue, and in glucose tolerance, and lower final body weight, muscle mass and total protein in blood when compared with C45 group. The HOMA-IR index was similar between LPHC45 and C45 groups, but this parameter was lower in LPHC45 compared with R groups. Serum adiponectin was higher in LPHC45 group than C45 and R groups. The R group presented higher fed insulin than C45 and LPHC45 and higher T4 compared with C45 group. Total cholesterol in R group was higher when compared with LPHC45 group. Thus, the data show that the change of the diet LPHC for a balanced diet led to different metabolic evolution and suggest that the different response can be due to different levels of adiponectin. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-01-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000300714 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/0001-3765201920180452 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
publisher.none.fl_str_mv |
Academia Brasileira de Ciências |
dc.source.none.fl_str_mv |
Anais da Academia Brasileira de Ciências v.91 n.2 2019 reponame:Anais da Academia Brasileira de Ciências (Online) instname:Academia Brasileira de Ciências (ABC) instacron:ABC |
instname_str |
Academia Brasileira de Ciências (ABC) |
instacron_str |
ABC |
institution |
ABC |
reponame_str |
Anais da Academia Brasileira de Ciências (Online) |
collection |
Anais da Academia Brasileira de Ciências (Online) |
repository.name.fl_str_mv |
Anais da Academia Brasileira de Ciências (Online) - Academia Brasileira de Ciências (ABC) |
repository.mail.fl_str_mv |
||aabc@abc.org.br |
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1754302867607388160 |