A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
Autor(a) principal: | |
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Data de Publicação: | 2008 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011 |
Resumo: | The aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels. |
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Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) |
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A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysiscompartment modelcarbon monoxidegas transportrespiratory systemair pollutionThe aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels.Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM2008-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011Journal of the Brazilian Society of Mechanical Sciences and Engineering v.30 n.3 2008reponame:Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)instname:Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)instacron:ABCM10.1590/S1678-58782008000300011info:eu-repo/semantics/openAccessAlbuquerque Neto,CyroYanagihara,Jurandir ItizoTurri,Fábioeng2008-10-07T00:00:00Zoai:scielo:S1678-58782008000300011Revistahttps://www.scielo.br/j/jbsmse/https://old.scielo.br/oai/scielo-oai.php||abcm@abcm.org.br1806-36911678-5878opendoar:2008-10-07T00:00Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) - Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)false |
dc.title.none.fl_str_mv |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
title |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
spellingShingle |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis Albuquerque Neto,Cyro compartment model carbon monoxide gas transport respiratory system air pollution |
title_short |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
title_full |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
title_fullStr |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
title_full_unstemmed |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
title_sort |
A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis |
author |
Albuquerque Neto,Cyro |
author_facet |
Albuquerque Neto,Cyro Yanagihara,Jurandir Itizo Turri,Fábio |
author_role |
author |
author2 |
Yanagihara,Jurandir Itizo Turri,Fábio |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Albuquerque Neto,Cyro Yanagihara,Jurandir Itizo Turri,Fábio |
dc.subject.por.fl_str_mv |
compartment model carbon monoxide gas transport respiratory system air pollution |
topic |
compartment model carbon monoxide gas transport respiratory system air pollution |
description |
The aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels. |
publishDate |
2008 |
dc.date.none.fl_str_mv |
2008-09-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S1678-58782008000300011 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM |
publisher.none.fl_str_mv |
Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM |
dc.source.none.fl_str_mv |
Journal of the Brazilian Society of Mechanical Sciences and Engineering v.30 n.3 2008 reponame:Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) instname:Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM) instacron:ABCM |
instname_str |
Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM) |
instacron_str |
ABCM |
institution |
ABCM |
reponame_str |
Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) |
collection |
Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) |
repository.name.fl_str_mv |
Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) - Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM) |
repository.mail.fl_str_mv |
||abcm@abcm.org.br |
_version_ |
1754734681377472512 |