A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis

Detalhes bibliográficos
Autor(a) principal: Albuquerque Neto,Cyro
Data de Publicação: 2008
Outros Autores: Yanagihara,Jurandir Itizo, Turri,Fábio
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011
Resumo: The aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels.
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spelling A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysiscompartment modelcarbon monoxidegas transportrespiratory systemair pollutionThe aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels.Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM2008-09-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011Journal of the Brazilian Society of Mechanical Sciences and Engineering v.30 n.3 2008reponame:Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)instname:Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)instacron:ABCM10.1590/S1678-58782008000300011info:eu-repo/semantics/openAccessAlbuquerque Neto,CyroYanagihara,Jurandir ItizoTurri,Fábioeng2008-10-07T00:00:00Zoai:scielo:S1678-58782008000300011Revistahttps://www.scielo.br/j/jbsmse/https://old.scielo.br/oai/scielo-oai.php||abcm@abcm.org.br1806-36911678-5878opendoar:2008-10-07T00:00Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) - Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)false
dc.title.none.fl_str_mv A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
title A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
spellingShingle A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
Albuquerque Neto,Cyro
compartment model
carbon monoxide
gas transport
respiratory system
air pollution
title_short A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
title_full A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
title_fullStr A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
title_full_unstemmed A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
title_sort A carbon monoxide transport model of the human respiratory system applied to urban atmosphere exposure analysis
author Albuquerque Neto,Cyro
author_facet Albuquerque Neto,Cyro
Yanagihara,Jurandir Itizo
Turri,Fábio
author_role author
author2 Yanagihara,Jurandir Itizo
Turri,Fábio
author2_role author
author
dc.contributor.author.fl_str_mv Albuquerque Neto,Cyro
Yanagihara,Jurandir Itizo
Turri,Fábio
dc.subject.por.fl_str_mv compartment model
carbon monoxide
gas transport
respiratory system
air pollution
topic compartment model
carbon monoxide
gas transport
respiratory system
air pollution
description The aim of this work is to analyze the carbon monoxide (CO) transport in the human body submitted to several physical activity levels. A complete mathematical model of the human respiratory system was developed, considering the exchanges of CO, oxygen (O2) and carbon dioxide (CO2) in the lung, blood and tissues. The human body was divided in the following compartments: alveolar, pulmonary capillaries, arterial, venous, tissue capillary and tissues. The gas transport in the blood and tissues is represented by empirical equations. The physiological parameters were described in function of physical activity. The model was validated by comparing its results with experimental data of controlled CO exposition. The agreement was excellent. CO concentration curves for critical days of São Caetano do Sul city (SP, Brazil) atmosphere were used as model input. The simulation results for some physical activities show that the more intense the activity, the larger the blood carboxyhemoglobin (COHb) level variations. The COHb level was compared with a CO quality air criteria, which showed to be adequate for low and moderate physical activity levels.
publishDate 2008
dc.date.none.fl_str_mv 2008-09-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S1678-58782008000300011
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S1678-58782008000300011
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM
publisher.none.fl_str_mv Associação Brasileira de Engenharia e Ciências Mecânicas - ABCM
dc.source.none.fl_str_mv Journal of the Brazilian Society of Mechanical Sciences and Engineering v.30 n.3 2008
reponame:Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)
instname:Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)
instacron:ABCM
instname_str Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)
instacron_str ABCM
institution ABCM
reponame_str Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)
collection Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online)
repository.name.fl_str_mv Journal of the Brazilian Society of Mechanical Sciences and Engineering (Online) - Associação Brasileira de Engenharia e Ciências Mecânicas (ABCM)
repository.mail.fl_str_mv ||abcm@abcm.org.br
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