Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400007 |
Resumo: | The role gap junction channels play in the normal and abnormal functioning of the vascular wall is the subject of much research. The biophysical properties of gap junctions are an essential component in understanding how gap junctions function to allow coordinated relaxation and contraction of vascular smooth muscle. This study reviews the properties thus far elucidated and relates those properties to tissue function. We ask how biophysical and structural properties such as gating, permselectivity, subconductive states and channel type (heteromeric vs homotypic vs heterotypic) might affect vascular smooth muscle tone. |
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Brazilian Journal of Medical and Biological Research |
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Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and diseasevascular smooth musclegap junctionsThe role gap junction channels play in the normal and abnormal functioning of the vascular wall is the subject of much research. The biophysical properties of gap junctions are an essential component in understanding how gap junctions function to allow coordinated relaxation and contraction of vascular smooth muscle. This study reviews the properties thus far elucidated and relates those properties to tissue function. We ask how biophysical and structural properties such as gating, permselectivity, subconductive states and channel type (heteromeric vs homotypic vs heterotypic) might affect vascular smooth muscle tone.Associação Brasileira de Divulgação Científica2000-04-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400007Brazilian Journal of Medical and Biological Research v.33 n.4 2000reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2000000400007info:eu-repo/semantics/openAccessBrink,P.R.Ricotta,J.Christ,G.J.eng2000-03-30T00:00:00Zoai:scielo:S0100-879X2000000400007Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2000-03-30T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
title |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
spellingShingle |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease Brink,P.R. vascular smooth muscle gap junctions |
title_short |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
title_full |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
title_fullStr |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
title_full_unstemmed |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
title_sort |
Biophysical characteristics of gap junctions in vascular wall cells: implications for vascular biology and disease |
author |
Brink,P.R. |
author_facet |
Brink,P.R. Ricotta,J. Christ,G.J. |
author_role |
author |
author2 |
Ricotta,J. Christ,G.J. |
author2_role |
author author |
dc.contributor.author.fl_str_mv |
Brink,P.R. Ricotta,J. Christ,G.J. |
dc.subject.por.fl_str_mv |
vascular smooth muscle gap junctions |
topic |
vascular smooth muscle gap junctions |
description |
The role gap junction channels play in the normal and abnormal functioning of the vascular wall is the subject of much research. The biophysical properties of gap junctions are an essential component in understanding how gap junctions function to allow coordinated relaxation and contraction of vascular smooth muscle. This study reviews the properties thus far elucidated and relates those properties to tissue function. We ask how biophysical and structural properties such as gating, permselectivity, subconductive states and channel type (heteromeric vs homotypic vs heterotypic) might affect vascular smooth muscle tone. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000-04-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400007 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2000000400007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/S0100-879X2000000400007 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.33 n.4 2000 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
_version_ |
1754302930435964928 |