Detection of acute cerebral hemorrhage in rabbits by magnetic induction
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Brazilian Journal of Medical and Biological Research |
Texto Completo: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200144 |
Resumo: | Acute cerebral hemorrhage (ACH) is an important clinical problem that is often monitored and studied with expensive devices such as computed tomography, magnetic resonance imaging, and positron emission tomography. These devices are not readily available in economically underdeveloped regions of the world, emergency departments, and emergency zones. We have developed a less expensive tool for non-contact monitoring of ACH. The system measures the magnetic induction phase shift (MIPS) between the electromagnetic signals on two coils. ACH was induced in 6 experimental rabbits and edema was induced in 4 control rabbits by stereotactic methods, and their intracranial pressure and heart rate were monitored for 1 h. Signals were continuously monitored for up to 1 h at an exciting frequency of 10.7 MHz. Autologous blood was administered to the experimental group, and saline to the control group (1 to 3 mL) by injection of 1-mL every 5 min. The results showed a significant increase in MIPS as a function of the injection volume, but the heart rate was stable. In the experimental (ACH) group, there was a statistically significant positive correlation of the intracranial pressure and MIPS. The change of MIPS was greater in the ACH group than in the control group. This high-sensitivity system could detect a 1-mL change in blood volume. The MIPS was significantly related to the intracranial pressure. This observation suggests that the method could be valuable for detecting early warning signs in emergency medicine and critical care units. |
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Detection of acute cerebral hemorrhage in rabbits by magnetic inductionAcute cerebral hemorrhageMagnetic induction phase shiftElectromagnetic properties of biological tissuesIntracranial pressureAcute cerebral hemorrhage (ACH) is an important clinical problem that is often monitored and studied with expensive devices such as computed tomography, magnetic resonance imaging, and positron emission tomography. These devices are not readily available in economically underdeveloped regions of the world, emergency departments, and emergency zones. We have developed a less expensive tool for non-contact monitoring of ACH. The system measures the magnetic induction phase shift (MIPS) between the electromagnetic signals on two coils. ACH was induced in 6 experimental rabbits and edema was induced in 4 control rabbits by stereotactic methods, and their intracranial pressure and heart rate were monitored for 1 h. Signals were continuously monitored for up to 1 h at an exciting frequency of 10.7 MHz. Autologous blood was administered to the experimental group, and saline to the control group (1 to 3 mL) by injection of 1-mL every 5 min. The results showed a significant increase in MIPS as a function of the injection volume, but the heart rate was stable. In the experimental (ACH) group, there was a statistically significant positive correlation of the intracranial pressure and MIPS. The change of MIPS was greater in the ACH group than in the control group. This high-sensitivity system could detect a 1-mL change in blood volume. The MIPS was significantly related to the intracranial pressure. This observation suggests that the method could be valuable for detecting early warning signs in emergency medicine and critical care units.Associação Brasileira de Divulgação Científica2014-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200144Brazilian Journal of Medical and Biological Research v.47 n.2 2014reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/1414-431X20132978info:eu-repo/semantics/openAccessSun,J.Jin,G.Qin,M.X.Wan,Z.B.Wang,J.B.Wang,C.Guo,W.Y.Xu,L.Ning,X.Xu,J.Pu,X.J.Chen,M.S.Zhao,H.M.eng2015-09-04T00:00:00Zoai:scielo:S0100-879X2014000200144Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2015-09-04T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false |
dc.title.none.fl_str_mv |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
title |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
spellingShingle |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction Sun,J. Acute cerebral hemorrhage Magnetic induction phase shift Electromagnetic properties of biological tissues Intracranial pressure |
title_short |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
title_full |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
title_fullStr |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
title_full_unstemmed |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
title_sort |
Detection of acute cerebral hemorrhage in rabbits by magnetic induction |
author |
Sun,J. |
author_facet |
Sun,J. Jin,G. Qin,M.X. Wan,Z.B. Wang,J.B. Wang,C. Guo,W.Y. Xu,L. Ning,X. Xu,J. Pu,X.J. Chen,M.S. Zhao,H.M. |
author_role |
author |
author2 |
Jin,G. Qin,M.X. Wan,Z.B. Wang,J.B. Wang,C. Guo,W.Y. Xu,L. Ning,X. Xu,J. Pu,X.J. Chen,M.S. Zhao,H.M. |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Sun,J. Jin,G. Qin,M.X. Wan,Z.B. Wang,J.B. Wang,C. Guo,W.Y. Xu,L. Ning,X. Xu,J. Pu,X.J. Chen,M.S. Zhao,H.M. |
dc.subject.por.fl_str_mv |
Acute cerebral hemorrhage Magnetic induction phase shift Electromagnetic properties of biological tissues Intracranial pressure |
topic |
Acute cerebral hemorrhage Magnetic induction phase shift Electromagnetic properties of biological tissues Intracranial pressure |
description |
Acute cerebral hemorrhage (ACH) is an important clinical problem that is often monitored and studied with expensive devices such as computed tomography, magnetic resonance imaging, and positron emission tomography. These devices are not readily available in economically underdeveloped regions of the world, emergency departments, and emergency zones. We have developed a less expensive tool for non-contact monitoring of ACH. The system measures the magnetic induction phase shift (MIPS) between the electromagnetic signals on two coils. ACH was induced in 6 experimental rabbits and edema was induced in 4 control rabbits by stereotactic methods, and their intracranial pressure and heart rate were monitored for 1 h. Signals were continuously monitored for up to 1 h at an exciting frequency of 10.7 MHz. Autologous blood was administered to the experimental group, and saline to the control group (1 to 3 mL) by injection of 1-mL every 5 min. The results showed a significant increase in MIPS as a function of the injection volume, but the heart rate was stable. In the experimental (ACH) group, there was a statistically significant positive correlation of the intracranial pressure and MIPS. The change of MIPS was greater in the ACH group than in the control group. This high-sensitivity system could detect a 1-mL change in blood volume. The MIPS was significantly related to the intracranial pressure. This observation suggests that the method could be valuable for detecting early warning signs in emergency medicine and critical care units. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014-02-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200144 |
url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2014000200144 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
10.1590/1414-431X20132978 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
text/html |
dc.publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
publisher.none.fl_str_mv |
Associação Brasileira de Divulgação Científica |
dc.source.none.fl_str_mv |
Brazilian Journal of Medical and Biological Research v.47 n.2 2014 reponame:Brazilian Journal of Medical and Biological Research instname:Associação Brasileira de Divulgação Científica (ABDC) instacron:ABDC |
instname_str |
Associação Brasileira de Divulgação Científica (ABDC) |
instacron_str |
ABDC |
institution |
ABDC |
reponame_str |
Brazilian Journal of Medical and Biological Research |
collection |
Brazilian Journal of Medical and Biological Research |
repository.name.fl_str_mv |
Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC) |
repository.mail.fl_str_mv |
bjournal@terra.com.br||bjournal@terra.com.br |
_version_ |
1754302942551212032 |