Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients

Detalhes bibliográficos
Autor(a) principal: Zimmermann,C.S.
Data de Publicação: 2007
Outros Autores: Carvalho,C.R.F., Silveira,K.R., Yamaguti,W.P.S., Moderno,E.V., Salge,J.M., Kairalla,R.A., Carvalho,C.R.R.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Brazilian Journal of Medical and Biological Research
Texto Completo: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200004
Resumo: The objective of the present study was to determine if there is a health-related quality of life (HRQL) instrument, generic or specific, that better represents functional capacity dysfunction in idiopathic pulmonary fibrosis (IPF) patients. HRQL was evaluated in 20 IPF patients using generic and specific questionnaires (Medical Outcomes Short Form 36 (SF-36) and Saint George's Respiratory Questionnaire (SGRQ), respectively). Functional status was evaluated by pulmonary function tests, 6-min walking distance test (6MWDT) and dyspnea indexes (baseline dyspnea index) at rest and after exercise (modified Borg scale). There was a restrictive pattern with impairment of diffusion capacity (total lung capacity, TLC = 71.5 ± 15.6%, forced vital capacity = 70.4 ± 19.4%, and carbon monoxide diffusing capacity = 41.5 ± 16.2% of predicted value), a reduction in exercise capacity (6MWDT = 435.6 ± 95.5 m) and an increase of perceived dyspnea score at rest and during exercise (6 ± 2.5 and 7.1 ± 1.3, respectively). Both questionnaires presented correlation with some functional parameters (TLC, forced expiratory volume in 1 s and carbon monoxide diffusing capacity) and the best correlation was with TLC. Almost all of the SGRQ domains presented a strong correlation with functional status, while in SF-36 only physical function and vitality presented a good correlation with functional status. Dyspnea index at rest and 6MWDT also presented a good correlation with HRQL. Our results suggest that a specific instead of a generic questionnaire is a more appropriate instrument for HRQL evaluation in IPF patients and that TLC is the functional parameter showing best correlation with HRQL.
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spelling Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patientsIdiopathic pulmonary fibrosisHealth-related quality of lifeFunctional statusThe objective of the present study was to determine if there is a health-related quality of life (HRQL) instrument, generic or specific, that better represents functional capacity dysfunction in idiopathic pulmonary fibrosis (IPF) patients. HRQL was evaluated in 20 IPF patients using generic and specific questionnaires (Medical Outcomes Short Form 36 (SF-36) and Saint George's Respiratory Questionnaire (SGRQ), respectively). Functional status was evaluated by pulmonary function tests, 6-min walking distance test (6MWDT) and dyspnea indexes (baseline dyspnea index) at rest and after exercise (modified Borg scale). There was a restrictive pattern with impairment of diffusion capacity (total lung capacity, TLC = 71.5 ± 15.6%, forced vital capacity = 70.4 ± 19.4%, and carbon monoxide diffusing capacity = 41.5 ± 16.2% of predicted value), a reduction in exercise capacity (6MWDT = 435.6 ± 95.5 m) and an increase of perceived dyspnea score at rest and during exercise (6 ± 2.5 and 7.1 ± 1.3, respectively). Both questionnaires presented correlation with some functional parameters (TLC, forced expiratory volume in 1 s and carbon monoxide diffusing capacity) and the best correlation was with TLC. Almost all of the SGRQ domains presented a strong correlation with functional status, while in SF-36 only physical function and vitality presented a good correlation with functional status. Dyspnea index at rest and 6MWDT also presented a good correlation with HRQL. Our results suggest that a specific instead of a generic questionnaire is a more appropriate instrument for HRQL evaluation in IPF patients and that TLC is the functional parameter showing best correlation with HRQL.Associação Brasileira de Divulgação Científica2007-02-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersiontext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200004Brazilian Journal of Medical and Biological Research v.40 n.2 2007reponame:Brazilian Journal of Medical and Biological Researchinstname:Associação Brasileira de Divulgação Científica (ABDC)instacron:ABDC10.1590/S0100-879X2006005000056info:eu-repo/semantics/openAccessZimmermann,C.S.Carvalho,C.R.F.Silveira,K.R.Yamaguti,W.P.S.Moderno,E.V.Salge,J.M.Kairalla,R.A.Carvalho,C.R.R.eng2008-02-12T00:00:00Zoai:scielo:S0100-879X2007000200004Revistahttps://www.bjournal.org/https://old.scielo.br/oai/scielo-oai.phpbjournal@terra.com.br||bjournal@terra.com.br1414-431X0100-879Xopendoar:2008-02-12T00:00Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)false
dc.title.none.fl_str_mv Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
title Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
spellingShingle Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
Zimmermann,C.S.
Idiopathic pulmonary fibrosis
Health-related quality of life
Functional status
title_short Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
title_full Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
title_fullStr Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
title_full_unstemmed Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
title_sort Comparison of two questionnaires which measure the health-related quality of life of idiopathic pulmonary fibrosis patients
author Zimmermann,C.S.
author_facet Zimmermann,C.S.
Carvalho,C.R.F.
Silveira,K.R.
Yamaguti,W.P.S.
Moderno,E.V.
Salge,J.M.
Kairalla,R.A.
Carvalho,C.R.R.
author_role author
author2 Carvalho,C.R.F.
Silveira,K.R.
Yamaguti,W.P.S.
Moderno,E.V.
Salge,J.M.
Kairalla,R.A.
Carvalho,C.R.R.
author2_role author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Zimmermann,C.S.
Carvalho,C.R.F.
Silveira,K.R.
Yamaguti,W.P.S.
Moderno,E.V.
Salge,J.M.
Kairalla,R.A.
Carvalho,C.R.R.
dc.subject.por.fl_str_mv Idiopathic pulmonary fibrosis
Health-related quality of life
Functional status
topic Idiopathic pulmonary fibrosis
Health-related quality of life
Functional status
description The objective of the present study was to determine if there is a health-related quality of life (HRQL) instrument, generic or specific, that better represents functional capacity dysfunction in idiopathic pulmonary fibrosis (IPF) patients. HRQL was evaluated in 20 IPF patients using generic and specific questionnaires (Medical Outcomes Short Form 36 (SF-36) and Saint George's Respiratory Questionnaire (SGRQ), respectively). Functional status was evaluated by pulmonary function tests, 6-min walking distance test (6MWDT) and dyspnea indexes (baseline dyspnea index) at rest and after exercise (modified Borg scale). There was a restrictive pattern with impairment of diffusion capacity (total lung capacity, TLC = 71.5 ± 15.6%, forced vital capacity = 70.4 ± 19.4%, and carbon monoxide diffusing capacity = 41.5 ± 16.2% of predicted value), a reduction in exercise capacity (6MWDT = 435.6 ± 95.5 m) and an increase of perceived dyspnea score at rest and during exercise (6 ± 2.5 and 7.1 ± 1.3, respectively). Both questionnaires presented correlation with some functional parameters (TLC, forced expiratory volume in 1 s and carbon monoxide diffusing capacity) and the best correlation was with TLC. Almost all of the SGRQ domains presented a strong correlation with functional status, while in SF-36 only physical function and vitality presented a good correlation with functional status. Dyspnea index at rest and 6MWDT also presented a good correlation with HRQL. Our results suggest that a specific instead of a generic questionnaire is a more appropriate instrument for HRQL evaluation in IPF patients and that TLC is the functional parameter showing best correlation with HRQL.
publishDate 2007
dc.date.none.fl_str_mv 2007-02-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000200004
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dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1590/S0100-879X2006005000056
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eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
publisher.none.fl_str_mv Associação Brasileira de Divulgação Científica
dc.source.none.fl_str_mv Brazilian Journal of Medical and Biological Research v.40 n.2 2007
reponame:Brazilian Journal of Medical and Biological Research
instname:Associação Brasileira de Divulgação Científica (ABDC)
instacron:ABDC
instname_str Associação Brasileira de Divulgação Científica (ABDC)
instacron_str ABDC
institution ABDC
reponame_str Brazilian Journal of Medical and Biological Research
collection Brazilian Journal of Medical and Biological Research
repository.name.fl_str_mv Brazilian Journal of Medical and Biological Research - Associação Brasileira de Divulgação Científica (ABDC)
repository.mail.fl_str_mv bjournal@terra.com.br||bjournal@terra.com.br
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